MicroRNA-mediated hypoxia vs cancer (1)

(click to enlarge)
The answer to the question Why have microRNA biomarkers not been translated from bench to clinic? appears in SETD3 is regulated by a couple of microRNAs and plays opposing roles in proliferation and metastasis of hepatocellular carcinoma 10/22/19
These findings were in line with the study conducted by Cheng et al. [15], who reported that SETD3 could be phosphorylated by the kinase glycogen synthase kinase 3 (GSK3b), which induced the FBXW7-mediated ubiquitination and degradation for SETD3. As an established post-transcriptional regulator, miRNA played important roles in facilitating degradation or blocking translation for many histone methyltransferases. In HCC, underexpression of miR-29a contribute to the up-regulation of SETDB1 [8]. Underexpression of miR-125b also facilitates SUV39H1 overexpression [9]. In this study, we identified that SETD3 could be regulated by a couple of miRNAs (miR-16, miR-195 and miR-497) at the post-transcriptional step, while the mRNA level of SETD3 was not significantly altered by these miRNAs. These results provided a new avenue to explain the inconsistence of SETD3 between mRNA and protein levels.
The ‘inconsistence’ arises in the context of the energy-dependent light-activated assembly of the microRNA-RNA-peptide nanocomplex, which links the Creation of oxygen from the Creation of sunlight and water to oxidative phosphorylation, which biophysically constrains viral latency in all cell types of all individualsย in all species that develop tissue-specific cancers.
Conflicts of interests among those who do not want to cure cancer ensure that drug developers outside Iran and China “follow the money,” not the scientific truth about oxidative phophorylation and biophysically constrained viral latency. The scientific truth can be viewed in the context of specialization by the drug developers who ignore it.
For comparison, see: ย Range: Why Generalists Triumph in a Specialized World 5/28/19
My summary: When he learned what was known about geology, Darwin went wrong. He turned to the ‘left.’ His “Conditions of life” (aka sunlight, water + oxygen-dependent ecological adaptations) across 5-10,000 years, changed to speculation about conditions of death.
Others turned to the ‘left’ when they linked theories about millions of years of evolution to drug development.
Nothing was known to Darwin about the biophysically constrained energy-dependent functional structure of supercoiled DNA. Still, he repeatedly asserted the fact that “conditions of life” must come before natural selection. His “conditions of life” are still missing from the leftist perspectives of biologically uninformed science idiots. For example, most Democrats and other libtards seem to think that We are all mutants 3/16/14.
But see this advertisement: Amino acid analyzers help the search for new biotherapeutics
The use of high-throughput peptide screening technology can overcome challenges in novel drug discovery from natural sources.
Natural sources, such as food energy, biophysically constrain viral latency via the pheromone-controlled physiology of reproduction.
See: Regulatory effects of lncRNAs and miRNAs on autophagy in malignant tumorigenesis 9/28/18
…miRNAs can regulate cell autophagy by modulating targetting gene expression. In this review, we will provide an overview of lncRNAs and miRNAs in autophagy modulation and new insights into the underlying mechanisms, as well as their potential utilization in disease diagnosis, prognosis, and therapy.
See also: Olfaction regulates organismal proteostasis and longevity via microRNA-dependent signaling 2/18/19
…the proposed mechanism of food perception will stimulate further research on neuroendocrine brain-to-gut communication and may open the possibility for therapeutic interventions to improve proteostasis and organismal health via the sense of smell…
Here is the recently clarified link from the nutrient-dependent pheromone-controlled physiology of reproduction in nematodes to healthy human longevity via the sense of smell.
Recent Molecular Genetic Explorations of Caenorhabditis elegans MicroRNAs 6/28/18
1) Phosphoinositide 3-kinases (PI3Ks) are divided into three isoforms (class I, class II, and class III). The class I PI3K triggers mTOR signaling pathway and inhibits autophagy, while the class III isoform activates the autophagy by corresponding to Vps34.
2) Autophagy has been reported to either inhibit or promote cancer cell proliferation or tumorigenesis in model systems, suggesting that the role of autophagy in cancer is context dependent [6,7]. Moderate and effective autophagy can remove tumor cells and maintain homeostasis. However, impaired autophagy may reduce cell viability, and delayed elimination of apoptotic cells from the body may induce the development of cancer [8].
This citation obfuscates cause and effect via use of the term isoform-specific signalling.
5. Vanhaesebroeck B., et al. (2010) The emerging mechanisms of isoform-specific PI3K signalling. Nat. Rev. Mol. Cell Biol. 11, 329โ341 10.1038/nrm2882
The light-activated assembly of the microRNA-RNA-peptide nanocomplex is required for all energy-dependent isoform-specific signalling. That fact is buried in the extant literature via use of terms like these:
peptide isoform
“amino acid” isoform
microRNA isoform
These isoforms do not automagically create themselves.
Medical Definition of isoform. : any of two or more functionally similar proteins that have a similar but not identical amino acid sequence and are either encoded by different genes or by RNA transcripts from the same gene which have had different exons removed.
See for comparison: Gene isoform
Gene isoforms are mRNAs that are produced from the same locus but are different in their transcription start sites (TSSs), protein coding DNA sequences (CDSs) and/or untranslated regions (UTRs), potentially altering gene function.
Look at the definitions of all the highlighted/underlined terms, and you may be able to link food energy-dependent pheromone-controlled authphagy to the prevention of all virus-driven diseases because “The synthesis of RNA in isolated thymus nuclei is ATP dependent.” (1964)
If mutations led to the synthesis of RNA, there would be no need for autophagy.
Autophagy is the body’s way of cleaning out damaged cells, in order to regenerate newer, healthier cells…
Autophagy links the energy-dependent Creation of endogenous substrates to ecological adaptations, or from the virus-driven degradation of messenger RNA to mutations and all pathology. That fact does not exemplify any degree of so called evolutionary conservation. It exemplifies that fact that energy-dependent endogenous substrates, aka microRNAs, do not Create themselves.
The conflict between claims made by neo-Darwinian theorists and serious scientists has been placed into the context ofย The conflict between adaptation and dispersal for maintaining biodiversity in changing environments 9/30/19
These findings highlight the need to consider ecological and evolutionary processes together, or we risk underestimating how global change will impact biodiversity.
That fact presciently led to the teaching of evolution in Israeli middle schools.
Israeli Middle Schools School to Include Theory of Evolution 6/4/14
…learning about evolution is not the primary function of the decision, but rather to use it as a building block for students to learn more about their ecology.
The ecologically relevant patented cure for all virus-driven cancer was issued to researchers from Israel on 12/25/18.
See: Methods and compositions for identifying a peptide having an intermolecular interaction with a target of interest
Proof of concept
Want more on the same topic?
Swipe/Drag Left and Right To Browse Related Posts:
The Scent of Eros 1995 revisited (Chapter 6)
14 MIN READ
0
The Scent of Eros 1995 revisited (Chapter 5)
26 MIN READ
0
The Scent of Eros revisited 7/4/25 (Epilogue)
30 MIN READ
0
Algorithmic enzyme creation vs Godโs Creation (9)
2 MIN READ
0
Algorithmic enzyme creation vs God’s Creation (2)
3 MIN READ
0
Echo chamber or ecosystem (9)
8 MIN READ
0
Echo chamber or ecosystem (7)
3 MIN READ
0
miRNA-mediated autophagy (5)
3 MIN READ
0
Abhorrent atheistic algorithms (9)
6 MIN READ
0
Anti-Christian bias (10)
8 MIN READ
0
Moronic theorists (3)
2 MIN READ
0
miRNA-mediated Creation of enzymes (2)
2 MIN READ
0
The woke mind virus (3)
< 1 MIN READ
0
NGS vs 5th generation warfare (4)
< 1 MIN READ
0
miRNA-mediated predictions (5)
3 MIN READ
0
miRNA-mediated predictions (4)
2 MIN READ
0
Minimal level of conflict (8)
4 MIN READ
0
Total recall 6000 years (7)
2 MIN READ
0
Biogeochemical is geopolitical (8)
2 MIN READ
0
Biogeochemical is geopolitical (4)
3 MIN READ
0
WHO broke the breakthrough (2)
2 MIN READ
0
miRNA-mediated epigenetic effects (7)
< 1 MIN READ
0
The devil is in the dirt (2)
2 MIN READ
0
The devil is in the dirt (1)
2 MIN READ
0
Scientism, atheism and theology (10)
2 MIN READ
0
The physics of existence (4)
3 MIN READ
0
The physics of existence (3)
3 MIN READ
0
Separated we survive (2)
3 MIN READ
0
Codon optimality vs systemic fraud (9)
5 MIN READ
0
Epistemic corruption (8)
2 MIN READ
0
RNAi 2002 to AI 2021 (4)
3 MIN READ
0
RNAi 2002 to AI 2021 (3)
3 MIN READ
0
Orchestrated death of Jews et al., by Egyptians (2)
6 MIN READ
0
God’s microRNA-mediated Creation of genotypes (2)
2 MIN READ
0
Natural selection for adaptation (9)
< 1 MIN READ
0
MicroRNA-mediated population control (7)
4 MIN READ
0
Pheromones protect us from viruses (9)
5 MIN READ
0
Protonated RNA interference vs stupid theories (6)
4 MIN READ
0
Election day blues for fools who โvoted blueโ (2)
2 MIN READ
0
microRNA-mediated quantum error correction (2)
5 MIN READ
0
microRNA-mediated quantum error correction (1)
2 MIN READ
0
From optoribogenetics to HelioRiboGenetics (6)
3 MIN READ
0
The microRNA-mediated future of humanity (3)
3 MIN READ
0
CDC’s ignorance: from roots to shoots (3)
4 MIN READ
0
The tipping point (revisited): 100K (3)
3 MIN READ
0
The tipping point (revisited): 97K (2)
3 MIN READ
0
MicroRNA-mediated healthy longevity (4)
2 MIN READ
0
Dmitri Petrov refutes theistic evolution, again
3 MIN READ
0
microRNA-mediated sex differences (1)
2 MIN READ
0
The tipping point (revisited): 95K (5)
< 1 MIN READ
0
MicroRNAs biophysically constrain Virus-driven pathology (6)
3 MIN READ
0
MicroRNAs biophysically constrain Virus-driven pathology (5)
4 MIN READ
0
The tipping point (revisited): 91K (1)
3 MIN READ
0
Bastardized health care (6)
4 MIN READ
0
Weaponized health information (7)
4 MIN READ
0
Weaponized health communication (3)
4 MIN READ
0
Genetic endemism: apologetics vs epigenetics (1)
2 MIN READ
0
Kohl and Francoeur at 25 (5)
2 MIN READ
0
Virus-driven downsizing of the human brain (5)
5 MIN READ
0
Preprints obfuscate facts (2)
4 MIN READ
0
Two photon-linked biodiversity (3)
2 MIN READ
0
From microRNA.pro to quantumsouls.pro (3)
5 MIN READ
0
North Korea quietly thanks God that Trump is a Creationist (2)
3 MIN READ
0
SfN’s 2018 trap set for Democrats
2 MIN READ
0
Energy-dependent ‘futile cycles’ of autophagy
2 MIN READ
0
Creation vs evolution of ribonucleotide removal strategies (2)
2 MIN READ
0
ATP-fueled microRNA biogenesis and cancer therapy
9 MIN READ
0
Quantum initiation of cold chemistry vs Hypeology (3)
3 MIN READ
0
Estranged ‘White Coat Notes’ blogger exposes human idiocy (1)
5 MIN READ
0
The concept of a species (4)
2 MIN READ
0
The eternal significance of microRNAs and the Vietnam Memorial (1)
3 MIN READ
0
From quantum physics to quantum souls (4)
8 MIN READ
0
From quantum physics to quantum souls (3)
4 MIN READ
0
Epigenetic inheritance of spatiotemporal regulation
4 MIN READ
0
The eternal significance of microRNAs (7)
3 MIN READ
0
The eternal significance of microRNAs (5)
2 MIN READ
0
Ecological adaptations vs the randomness of evolution (3)
4 MIN READ
0
A single base change refutes theistic evolution
5 MIN READ
0
Environmental selection is natural selection (2)
2 MIN READ
0
MicroRNA-mediated denuclearization (2)
5 MIN READ
0
2018 March for Science vs microRNAs (2)
4 MIN READ
0
2018 March for Science vs microRNAs
7 MIN READ
0
The eternal significance of microRNAs (2)
3 MIN READ
0
The eternal significance of microRNAs (1)
< 1 MIN READ
0
Sympatric Speciation vs pseudosceintific nonsense (4)
2 MIN READ
0
Sympatric Speciation vs Pseudoscientific Nonsense (1)
4 MIN READ
0
Complexity: Routes and Patterns (4)
< 1 MIN READ
0
Laws of Biology / Rules of Life
3 MIN READ
0
Part 3: Light-controlled cell biology (revisited)
3 MIN READ
0
Light-controlled cell biology (revisited)
6 MIN READ
0
Autophagy in health and disease (1)
3 MIN READ
0
Death cures theorist’s Amyotrophic Lateral Sclerosis (ALS).
< 1 MIN READ
0
How to create biologically uninformed theorists
7 MIN READ
0
Carl Zimmer refutes theistic evolution (2)
2 MIN READ
0
Ecological adaptation: a new definition of heredity (4)
4 MIN READ
0
Ecological adaptation: A new definition of heredity (1)
5 MIN READ
0
Creating biophysically constrained viral latency (1)
4 MIN READ
0
Light-activated carbon fixation did not evolve (4)
7 MIN READ
0
Conceptual critique: Innateness vs the death gene (1)
5 MIN READ
0
Cryo-EM: Linking spatial and conformational constraints
9 MIN READ
0
A reversible TCA cycle in a thermophile
5 MIN READ
0
Diet-driven RNA interference and mental health (3)
4 MIN READ
0
BiondVax Universal Flu Vaccine Patent
4 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (4)
5 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (2)
6 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (1)
4 MIN READ
0
A mental health problem at the highest level (2)
3 MIN READ
0
Diet-driven RNA interference and cancer prevention (4)
4 MIN READ
0
Diet-driven RNA interference and cancer prevention (3)
6 MIN READ
0
Autophagy is the antiphage defense strategy (2)
4 MIN READ
0
Enzyme-constrained interethnic diversity (8)
< 1 MIN READ
0
Diet-driven RNA interference and cancer prevention
5 MIN READ
0
Enzyme-constrained interethnic biodiversity (6)
8 MIN READ
0
Enzyme-constrained interethnic biodiversity (1)
5 MIN READ
0
Quantized energy-dependent viral trophism (2)
2 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls (5)
4 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls (2)
3 MIN READ
0
A Mathematical Model Links Quantum Physics to Quantum Souls (1)
6 MIN READ
0
Who created your virus-driven death gene? (3)
3 MIN READ
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (3)
3 MIN READ
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (1)
3 MIN READ
0
Darwinian adaptation: a clear evolutionary trail?
4 MIN READ
0
The tipping point (revisited): 68,000 publications
5 MIN READ
0
Agilent technology and energy-dependent autophagy
8 MIN READ
0
Narcissistic egomaniacal and deadly denial of autophagy
6 MIN READ
0
Elsevier fails to support the concept of autophagy
4 MIN READ
0
From Autophagy.pro (transitions)
4 MIN READ
0
Nature vs Science and Autophagy.pro
7 MIN READ
0
Autophagy.pro vs Nature Publications Group
2 MIN READ
0
The overwhelming ignorance of sex researchers (2)
4 MIN READ
0
Trashing the 2nd Law
7 MIN READ
0
The overwhelming ignorance of sex researchers
5 MIN READ
0
Mouse morphs and primate diversity in 50 years
7 MIN READ
0
Vulgar Antagonists vs Quantum Effects
3 MIN READ
0
Who created your virus-driven death gene? (1)
5 MIN READ
0
Light-activated error free DNA repair (2)
8 MIN READ
0
Eutrophication and phosphorylated biodiversity
6 MIN READ
0
Alternative splicing: a new therapy?
3 MIN READ
0
Selfish X-linked alleles and X chromosome inactivation
3 MIN READ
0
Pheromones biophysically constrain base editing and RNA editing
3 MIN READ
0
From base editing to RNA editing (5)
< 1 MIN READ
0
From base editing to RNA editing (4)
5 MIN READ
0
The next reformation: 500 years too late? (3)
5 MIN READ
0
Cryo-EM: More than a suggestion
< 1 MIN READ
0
Long-term adaptation replaces evolution (2)
2 MIN READ
0
Exome Sequencing Impact in Routine Care
4 MIN READ
0
Virulence: Out of stock
2 MIN READ
0
Energy-dependent structure and function: Until death (3)
3 MIN READ
0
Energy-dependent structure and function: Until death (2)
5 MIN READ
0
Energy-dependent structure and function: Until death (1)
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (5)
2 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (4)
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (2)
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes
4 MIN READ
0
Methylation and the Innate Immune System
< 1 MIN READ
0
Sexual communication signals: New Insights!
10 MIN READ
0
God vs host-derived creation of virus-driven pathology (2)
4 MIN READ
0
God vs host-derived creation of virus-driven pathology
6 MIN READ
0
Stem cells do not create themselves
3 MIN READ
0
Pseudoscientists hate what science explains! (3)
4 MIN READ
0
Your indifference is killing you and others (3)
4 MIN READ
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4 MIN READ
0
Can protein folding chemistry be understood by theorists?
5 MIN READ
0
Evolutionary congruence (losers) vs ecological adaptation (winners)
3 MIN READ
0
Pattern recognition vs evolutionary processes (revisited)
7 MIN READ
0
Energy-dependent physical and biophysical constraints (9)
3 MIN READ
0
Energy-dependent physical and biophysical constraints (8)
5 MIN READ
0
Energy-dependent physical and biophysical constraints (5)
7 MIN READ
0
Energy-dependent physical and biophysical constraints (3)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (2)
4 MIN READ
0
Cell type assembly and the space-time continuum
2 MIN READ
0
God’s shrinking role in salvation (3)
9 MIN READ
0
God's shrinking role in salvation (3)
9 MIN READ
0
MicroRNAs GnRH and the failure of sex research
7 MIN READ
0
God’s shrinking role in salvation (2)
5 MIN READ
0
Hard Science vs the neo-Darwinian “magic box”
9 MIN READ
0
Food energy-dependent epigenetic adaptation (3)
3 MIN READ
0
Food energy-dependent epigenetic adaptation (2)
< 1 MIN READ
0
Food energy-dependent epigenetic adaptation
11 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (6)
8 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (4)
2 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability
8 MIN READ
0
Nothing evolved into all biodiversity on Earth
4 MIN READ
0
Energy-dependent microRNA biogenesis
4 MIN READ
0
Draining the academic swamp of parasites
3 MIN READ
0
Open Science: Closed to facts about microRNAs
6 MIN READ
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3 MIN READ
0
Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution
3 MIN READ
0
Functionally interdependent editing and methylation
4 MIN READ
0
Cytosis: Biology Content
7 MIN READ
0
Light-activated feedback loops vs self-organization of ecosystems
7 MIN READ
0
Sal Giardina: apologetics revisited
8 MIN READ
0
Who will kill the billion dollar baby? Bill Gates or Donald Trump
3 MIN READ
0
Food for thought: Penrose v Ellis (1)
5 MIN READ
0
Proof: Sunlight is energy as information
< 1 MIN READ
0
The essence of precision medicine
4 MIN READ
0
Allen Institute confirms food energy is information
6 MIN READ
0
Energy-dependent allelic imbalances, viruses, and pathology
3 MIN READ
0
Theistic evolutionists fight back and lose (3)
4 MIN READ
0
Theistic evolutionists fight back and lose
4 MIN READ
0
Young earth creationists refute theistic evolution
3 MIN READ
0
Charles Darwin refutes theistic evolution
2 MIN READ
0
RNA editing refutes theistic evolution
4 MIN READ
0
Pseudoscientists fail to refute theistic evolution
4 MIN READ
0
May the anti-entropic force of sunlight be with you
4 MIN READ
0
Francis S. Collins refutes theistic evolution
6 MIN READ
0
Happy Darwin Day (2017)
4 MIN READ
0
George Church refutes theistic evolution (3)
5 MIN READ
0
George Church refutes theistic evolution (2)
2 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science (2)
3 MIN READ
0
Natural selection for codon optimality and quantum viruses
5 MIN READ
0
Physicists: Desperate Acts (revisited)
6 MIN READ
0
Energy as information and constrained endogenous RNA interference (3)
4 MIN READ
0
Virus-driven energy theft and premature death
3 MIN READ
0
Dobzhansky 1973 and Precision Medicine (2)
5 MIN READ
0
Another failed attempt to address the malaria challenge
2 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Twisted theories and weaponized facts
3 MIN READ
0
Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.
6 MIN READ
0
Chirality, nutritional epigenetics, autophagy, and ethnicity
< 1 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Science journalists or paid propagandists? (3)
6 MIN READ
0
Critical values expose virus-driven energy theft (2)
4 MIN READ
0
Theorists sell hidden energy (2)
4 MIN READ
0
Critical values expose virus-driven energy theft
6 MIN READ
0
Theorists sell hidden energy
3 MIN READ
0
Anti-entropic energy and the “Music of Life”
3 MIN READ
0
Anti-entropic energy and the "Music of Life"
3 MIN READ
0
Evolved patterns of brain stimulation
3 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
Vietnam Veterans and others with glioblastoma
3 MIN READ
0
Energy-dependent sensory maps (1996-2016)
5 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016
12 MIN READ
0
Energy-dependent oscillating gene networks organize life
4 MIN READ
0
2016 obfuscated facts about energy as information
5 MIN READ
0
More refutations of neo-Darwinian nonsense
7 MIN READ
0
Re-inventing mutation-driven evolution (2)
4 MIN READ
0
Re-inventing mutation-driven evolution
3 MIN READ
0
Sudden death indel polymorphism
4 MIN READ
0
Bird-brained theorists
< 1 MIN READ
0
Expunging the distinguished public
2 MIN READ
0
Explorers who do not know what is known (2)
6 MIN READ
0
Explorers who do not know what is known
4 MIN READ
0
Autophagy is the antiphage defense strategy
3 MIN READ
0
Energy-dependent de novo creation and neurogenesis (2)
5 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Politicized science: The demise of RNA-mediated.com?
3 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Metabolic Phenotyping Research
2 MIN READ
0
Phylogenetic similarity sans energy
2 MIN READ
0
De novo gene creation: Ignoring the experimental evidence
7 MIN READ
0
Energy-dependent coulombic, autophagic, polycombic healthy longevity
4 MIN READ
0
Light, behavior and autophagy, a gender-specific risk factor
4 MIN READ
0
Controlled amino acid treatment of all pathology
4 MIN READ
0
Energy-dependent purifying selection / autophagy (2)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (3)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (4)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (5)
2 MIN READ
0
Energy-dependent purifying selection / autophagy
2 MIN READ
0
Optogenetics: Let there be virucidal light!
2 MIN READ
0
Theorists struggle with the concept of autophagy
2 MIN READ
0
Base pairs, amino acids and phenotypes
10 MIN READ
0
Survivors of RNA-mediated terrorism
5 MIN READ
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3 MIN READ
0
Building delicious base pairs in class. It's elementary Watson and Crick
3 MIN READ
0
RNA-mediated “repurposing” is autophagy
2 MIN READ
0
RNA-mediated "repurposing" is autophagy
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (8)
4 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Virus-driven mutation or amino acid substitution
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (7)
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (4)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (2)
2 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Polycombic ecological adaptation as a science, not a theory
3 MIN READ
0
80 years of causal analysis (1936 – 2016)
11 MIN READ
0
The natural success of RNAi and failed treatment
7 MIN READ
0
Pheromone-controlled autophagy
4 MIN READ
0
Virus-mediated hecatombic evolution
2 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Did evolution autophosphorylate your kinases?
5 MIN READ
1
Nutrient-dependent autophagy
3 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy (2)
6 MIN READ
0
The last RNA-mediated theory killer (2)
7 MIN READ
0
Asking the right questions (2)
3 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
The last RNA-mediated theory killer
< 1 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
Increased soil pH and nutrient availability
4 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Antithetical conclusions (7)
3 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (3)
< 1 MIN READ
0
Biophysically constrained cell type differentiation
3 MIN READ
0
From angstroms to ecosystems
7 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Q and A: Energy-dependent cell type differentiation
10 MIN READ
0
Virus-driven downsizing of the human brain
2 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
RNA methylation
2 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (5)
6 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
Wasted Templeton Funding (3)
2 MIN READ
0
Millions of water molecules vs years of evolution
2 MIN READ
0
Ricki Lewis’ Time Machine (4)
8 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Energy-dependent RNA-mediated immunity (1)
10 MIN READ
0
Science vs semantics
4 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Stress-induced energy-dependent DNA repair
4 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
MicroRNAs vs Red Queen hypothesis
4 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
MicroRNA-encoded behavior
7 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
RNA-mediated terms of virus-induced en-deer-ment
2 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Living the life that randomness created? (Sarcasm alert)
3 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
Batch effect vs epigenetic effects
3 MIN READ
0
Bee-birthed epigenetics and primate cell types
5 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
Epigenetics vs the fossil record
4 MIN READ
0
RNA-mediated cell types and precision medicine
5 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
2 genes in 2 species (too expensive and too insignificant)
11 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Correctly modeling biological energy
2 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
What about birds?
5 MIN READ
0
Reverse phosphorylation
7 MIN READ
0
RNA-mediated repurposing in microbes and adaptations in primate brains
2 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
An epigenetic trap (the prequel)
5 MIN READ
0
Imagining that data historically supports evolutionary theory
7 MIN READ
0
The anti-entropic force of "Nature"
2 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
Atoms to ecosystems is not almost a molecular ecology
3 MIN READ
0
Epigenetic effects of viruses on cellular homeostasis (2)
2 MIN READ
0
Biological energy and a microbiome model of a light-driven time machine
3 MIN READ
0
Quantum Superpositions: let there be light
4 MIN READ
0
Are viruses microRNAs? (2)
5 MIN READ
0
Sneaking up from behind
4 MIN READ
0
Beneficial microbes kill beneficial mutations
4 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
A single amino acid substitution differentiates cell types of E. coli
3 MIN READ
0
Unconstrained evolutionary innovability
4 MIN READ
0
Mutagenesis: Replacing facts with theories
5 MIN READ
0
ISHE's human ethology group
2 MIN READ
0
From Hydra to humans vs a Lakatosian research program
4 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Model organisms: the birds and the bees
3 MIN READ
0
Chemical ecology and RNA-mediated control of DNA loops
< 1 MIN READ
0
Jumping back: Science or Pseudoscience?
6 MIN READ
0
Single-cell level assay of protein biosynthesis and degradation
2 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
RNA-mediated species specificity
2 MIN READ
0
Are mutations beneficial?
4 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
Making sense of quotes scattered across disciplines
2 MIN READ
0
Intelligent viruses and cancers?
10 MIN READ
0
Sexual differentiation of cell types in plants
2 MIN READ
0
A model of MHC 'evolution'
2 MIN READ
0
From deep time into real time: What evolutionary processes?
10 MIN READ
0
Are evolutionary theorists 'nob ends'?
5 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
Nutrient-dependent gene duplication in plants (but not animals?)
4 MIN READ
0
Behavioral ecology: please continue to believe in our fantasies
3 MIN READ
0
RNA-mediated genetic engineering (Part 2)
3 MIN READ
0
RNA-mediated genetic engineering
2 MIN READ
0
Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
0
Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Ecological variation and niche construction: 1, 2, 3
6 MIN READ
0
Stop evolutionary theorists. Kill cancers
3 MIN READ
0
De novo gene Creation sans evolution of genes via mutations
4 MIN READ
0
Seemingly futile cycles are not thermodynamically futile
3 MIN READ
0
Memory of repression and memory of behavior
2 MIN READ
0
Exploding genomes and chromosomal rearrangements via RNA-mediated events
2 MIN READ
0
Behavior (2): All responses are RNA-mediated not genetically-determined
4 MIN READ
0
Biophysically constrained beginnings of RNA and DNA
4 MIN READ
0
Baby talk: More misrepresentations of ecological adaptations
2 MIN READ
0
Epimutations: Attacking pseudoscientific dogmas
4 MIN READ
0
Order and disorder: Ecological adaptations not mutations
6 MIN READ
0
The quantum biology of consciousness
3 MIN READ
0
Cell-type differentiation
2 MIN READ
0
96 fixed amino acid substitutions, not 96 genes
6 MIN READ
0
Social experiences epigenetically effect gene networks
2 MIN READ
0
Pheromone-controlled thermodynamics and cancer
2 MIN READ
0
Honeybees, food odors, and perfume
< 1 MIN READ
0