How to Profit from Suffering and Death (2)

By: James V. Kohl | Published on: November 18, 2019

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Epigenetic Regulator CoREST Controls Social Behavior in Ants 11/12/19
Excerpt:

CoREST RNAi (compared to control RNAi) was injected into the head capsule of Major ants at d4, and then TSA (or DMSO control) was injected 24 h later at d5, the peak time of reprogramming (scheme in Figure 6A; validation of CoREST RNAi in Figures S5A and S5B).

Conclusion:

Our data indicate that CoREST directly represses JH-degrading enzymes in the brain, however, given that endocrine systems frequently employ multiple feedback mechanisms and complex interactions, and given that the developmental decision between Major and Minor worker is made in the larval stage of development, it thus remains unclear whether the CoREST-represses-JH axis is downstream of another hormonal signal set up earlier in development.

See the comment by psychiatrist, Jay R. Feierman:
175862 Epigenetic Programming of Social Behavior OPEN ACCESS

Coming soon to humans! — Jay R. Feierman

See for comparison: “Dynamic modulation of the gut microbiota and metabolome by bacteriophages in a mouse model” 6/12/19
It links the nutrient-dependent pheromone-controlled physiology of microbes and mammals to healthy longevity. That fact was contextualized in [Pheromonal regulation of genetic processes: research on the house mouse (Mus musculus L.)] (1994)
Jay R. Feierman bastardized all the facts. I linked them to healthy longevity in humans via my model. Nutrient-dependent/pheromone-controlled adaptive evolution: a model (2013)
On 7/25/13 Feierman claimed:

“Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you don’t know that you have an incorrect understanding [of] Darwinian biological evolution.“

Via his flippant comment: “Coming soon to humans!” — Jay R. Feierman attests to the fact that he exemplifies a history of human idiocy in the context of Feynman’s claim about where the energy for RNA-mediated cell type differentiation via biophysically constrained RNA interference comes from. See: Richard Feynman on units of energy (video)
See for comparison, Jay R. Feierman’s constant focus on mutations and evolution during his tenure as moderator of the soon to be defunct “Human Ethology” Yahoo Group.
“Starting December 14, 2019 Yahoo Groups will no longer host user created content on its sites. New content can no longer be uploaded after October 28, 2019.”
Jay R. Feierman (7/26/13):

“I am absolutely certain that if you showed this statement to any professor of biology or genetics in any accredited university anywhere in the world that 100% of them would say that “Random mutations are the substrate upon which directional natural selection acts” is a correct and true statement.

… Your arrogance amazes me. It would be like me saying that gravity does not cause items with mass to fall to earth at 32 feet/sec/sec in a vacuum as that is how fundamental the statement that random mutations are the substrate upon which directional natural selection acts is to biology and genetics. You really want us to believe that you are the expert on this topic when 100% of university level biology textbooks for Biology 101 and all biology and genetics professors will say the exact same sentence or something almost identical.”

See for comparison: Tracking niche variation over millennial timescales in sympatric killer whale lineages 8/14/13

Ecological variation is the raw material by which natural selection can drive evolutionary divergence [1–4].

The differences in amino acid composition among different tissues can lead to large differences in trophic discrimination [38].