microRNA-mediated sex differences (1)

(click to enlarge)
For recent support of our claims from 23 years ago, see: Sexual dimorphism of miRNA signatures in feto-placental endothelial cells is associated with altered barrier function and actin organisation (Dec 2019)
We used our well established model of fetal endothelial cells isolated from placenta (fpEC) and analysed sexual dimorphic miRNA expression and potentially affected biological functions.
Functional pathways most significantly regulated by these miRNAs included ‘Adherens junction’, ‘ECM receptor interaction’ and ‘Focal adhesion’. These pathways control monolayer barrier function and may be paralleled by altered cytoskeletal organization.
See for review: From Fertilization to Adult Sexual Behavior (Dec 1996)
Here the “environment” involved can be that within a DNA segment. We also expand the notion of “biologically based sex differences.” Although many, and perhaps most, important sex differences arise from gonadal and hormonal development, also important are sex differences which are neither gonadal nor hormonal.
Cited by 50
See our section on molecular epigenetics. You can link our claims about the nutrient-dependent pheromone-controlled alternative splicing of pre-mRNA to miRNA-mediated fixation of amino acid substitutions and to sexual differentiation of cell types from yeasts to humans.
Yet another kind of epigenetic imprinting occurs in species as diverse as yeast, Drosophila, mice, and humans and is based upon small DNA-binding proteins called “chromo domain” proteins, e.g., polycomb. These proteins affect chromatin structure, often in telomeric regions, and thereby affect transcription and silencing of various genes (Saunders, Chue, Goebl, Craig, Clark, Powers, Eissenberg, Elgin, Rothfield, and Earnshaw, 1993; Singh, Miller, Pearce, Kothary, Burton, Paro, James, and Gaunt, 1991; Trofatter, Long, Murrell, Stotler, Gusella, and Buckler, 1995). Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans (Adler and Hajduk, 1994; de Bono, Zarkower, and Hodgkin, 1995; Ge, Zuo, and Manley, 1991; Green, 1991; Parkhurst and Meneely, 1994; Wilkins, 1995; Wolfner, 1988). That similar proteins perform functions in humans suggests the possibility that some human sex differences may arise from alternative splicings of otherwise identical genes.
For support of ridiculous theories that might link abiogenesis from the evolution of self-replicating ribozymes (1) to the biophysically constrained (2) topology of supercoiled DNA, which protects all organized genomes from the virus-driven degradation of messenger RNA and stress-linked pathology, see:
Genetic dissection of assortative mating behavior 2/7/19
“Ecologically relevant mating cues (sometimes known as “magic traits” [2,6]) are now predicted to be widespread in nature [6,7], and the last few years have seen considerable progress in our understanding of their genetic basis.”
(1) Lipid Encapsulation of Self-Replicating Ribozymes by Nurse Andrew Jones
(2) Dna Topology by Nurse Andrew Jones
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4 MIN READ
0
RNA-mediated silencing (7)
3 MIN READ
0
RNA-mediated silencing (2)
4 MIN READ
0
Photonics in Forensics (10)
3 MIN READ
0
Photonics in Forensics (8)
4 MIN READ
0
Photonics in Forensics (7)
3 MIN READ
0
Photonics in Forensics (6)
2 MIN READ
0
microRNA-mediated biodiversity (6)
3 MIN READ
0
microRNA-mediated biodiversity (4)
2 MIN READ
0
microRNA-mediated biodiversity (3)
4 MIN READ
0
Naturally attenuated viral endemicity (8)
3 MIN READ
0
Orchestrated death: Francis S. Collins (2)
4 MIN READ
0
Orchestrated death: J. Michael Bailey
4 MIN READ
0
MicroRNA-mediated population control (7)
4 MIN READ
0
MicroRNA-mediated population control (3)
3 MIN READ
0
MicroRNA-mediated population control (2)
3 MIN READ
0
microRNA-mediated election cycles (6)
3 MIN READ
0
microRNA-mediated replication timing (5)
3 MIN READ
0
Defeating disease and Communism (3)
2 MIN READ
0
Impeaching the God of Abraham (8)
4 MIN READ
0
God’s protection from SARS COV-2 and other viruses (2)
4 MIN READ
0
Suffering and loss of life by “voting blue” (1)
2 MIN READ
0
Protonated RNA interference vs stupid theories (4)
< 1 MIN READ
0
microRNA-mediated quantum error correction (4)
2 MIN READ
0
Optoribogenetic-driven sympatric speciation (1)
3 MIN READ
0
pH-dependent viral latency (3)
4 MIN READ
0
pH-dependent viral latency (2)
3 MIN READ
0
The microRNA-mediated future of humanity (6)
4 MIN READ
0
The microRNA-mediated future of humanity (3)
3 MIN READ
0
FDA’s ignorance: From roots to shoots (2)
3 MIN READ
0
CDC’s ignorance: from roots to shoots (3)
4 MIN READ
0
The tipping point (revisited): 100K (2)
5 MIN READ
0
NIH’s ignorance: From roots to shoots (1)
4 MIN READ
0
FDA’s ignorance: From roots to shoots (1)
6 MIN READ
0
The tipping point (revisited): 99K (1)
6 MIN READ
0
Transposons: crossroads, crosstalk and gene regulation
7 MIN READ
0
Richard Axel refutes theistic evolution
2 MIN READ
0
MicroRNA-mediated healthy longevity (4)
2 MIN READ
0
The tipping point (revisited): 95K (2)
2 MIN READ
0
The tipping point (revisited): 95K (1)
< 1 MIN READ
0
MicroRNAs biophysically constrain Virus-driven pathology (6)
3 MIN READ
0
Viral latency vs secular humanism (1)
2 MIN READ
0
MicroRNAs on Veteran’s Day 2019
< 1 MIN READ
0
MicroRNA-mediated hypoxia vs cancer (1)
5 MIN READ
0
2020 National Vaccine Plan (1)
2 MIN READ
0
The memory of oxygen (1)
5 MIN READ
0
#SFN2019 to 2012: Hiding the facts (7)
2 MIN READ
0
#SFN2019 to 2012: Hiding the facts (1)
3 MIN READ
0
Patented Creation vs Evolution of Disease (9)
4 MIN READ
0
Patented Creation vs Evolution of Disease (6)
4 MIN READ
0
Chemogenetic kinetics (7): DHA vs consensus (4)
3 MIN READ
0
Chemogenetic kinetics (7): DHA vs consensus (3)
3 MIN READ
0
Chemogenetic kinetics (4): Darwinism vs neo-Darwinism
2 MIN READ
0
Light-activated chemogenetic kinetics (2)
4 MIN READ
0
Light-activated chemogenetic kinetics (1)
2 MIN READ
0
Nutrient-dependent Pheromone-controlled cures (4)
2 MIN READ
0
Nutrient-dependent Pheromone-controlled cures (3)
4 MIN READ
0
Lewis Thomas (revisited): 90K (1)
5 MIN READ
0
The tipping point (revisited) 90K (4)
4 MIN READ
0
Sunlight, hydrophobicity and biodiversity (3)
5 MIN READ
0
Bastardized health care (3)
4 MIN READ
0
Bastardized health care (2)
3 MIN READ
0
Weaponized health communication (3)
4 MIN READ
0
The tipping point (revisited): 89K (2)
2 MIN READ
0
Genetic endemism: apologetics vs epigenetics (1)
2 MIN READ
0
Relatable not debatable (1)
4 MIN READ
0
The tipping point (revisited): G6PD
4 MIN READ
0
The tipping point (revisited): 85,000 publications (3)
3 MIN READ
0
Virus-driven downsizing of the human brain (6)
6 MIN READ
0
Constraints on microRNAs: Buried in patents
5 MIN READ
0
DS Wilson’s view of biophysically constrained life (3)
3 MIN READ
0
DS Wilson’s view of biophysically constrained life (2)
2 MIN READ
0
Preprints obfuscate facts (2)
4 MIN READ
0
Ecological adaptation vs neo-Darwinian nonsense (5)
4 MIN READ
0
10,000 reasons to believe in biophysical constraints (revisited)
< 1 MIN READ
0
Light-activated continuous environmental tracking (2)
3 MIN READ
0
Light-activated constrained biodiversity
7 MIN READ
0
Light-activated carbon fixation (1)
2 MIN READ
0
The tipping point (revisited): 81,000 publications (2)
2 MIN READ
0
The tipping point (revisited): 81,000 publications (1)
5 MIN READ
0
Hide and seek with science facts (7)
3 MIN READ
0
Hide and seek with science facts (2)
3 MIN READ
0
Electrons build fractal shapes and prevent lung cancer
2 MIN READ
0
Quantum initiation of cold chemistry vs Hypeology (3)
3 MIN READ
0
Virus-driven genome engineering causes cancer?
2 MIN READ
0
The tipping point (revisited): 74,000 publications
4 MIN READ
0
Biologically uninformed science idiot: Self-defense (4)
4 MIN READ
0
The eternal significance of microRNAs and the Vietnam Memorial (1)
3 MIN READ
0
From quantum physics to quantum souls (2)
2 MIN READ
0
Epigenetic inheritance of spatiotemporal regulation (3)
5 MIN READ
0
Epigenetic inheritance of spatiotemporal regulation
4 MIN READ
0
The eternal significance of microRNAs (7)
3 MIN READ
0
The eternal significance of microRNAs (5)
2 MIN READ
0
A single base change refutes theistic evolution (2)
2 MIN READ
0
Ecological adaptations vs the randomness of evolution (3)
4 MIN READ
0
EDAR V370A and sympatric speciation
2 MIN READ
0
Environmental selection is natural selection (2)
2 MIN READ
0
Abiogenesis vs microRNA biogenesis (3)
2 MIN READ
0
2018 March for Science vs microRNAs
7 MIN READ
0
The eternal significance of microRNAs (1)
< 1 MIN READ
0
Sympatric Speciation vs pseudosceintific nonsense (4)
2 MIN READ
0
Sympatric Speciation vs Pseudoscientific Nonsense (1)
4 MIN READ
0
Complexity: Routes and Patterns (4)
< 1 MIN READ
0
Is meat protein unhealthy? (2)
2 MIN READ
0
Is meat protein unhealthy? (1)
< 1 MIN READ
0
Laws of Biology / Rules of Life
3 MIN READ
0
Complexity: Routes and Patterns (2)
< 1 MIN READ
0
Part 3: Light-controlled cell biology (revisited)
3 MIN READ
0
Polymaths and paradigm shifts: from Asimov to Bear (3)
3 MIN READ
0
Ecological adaptation: a new definition of heredity (4)
4 MIN READ
0
Ecological adaptation: A new definition of heredity (3)
4 MIN READ
0
Ecological adaptation: A new definition of heredity (1)
5 MIN READ
0
MicroRNAs biophysically constrain behavior (2)
3 MIN READ
0
Conceptual critique: Innateness vs the death gene (1)
5 MIN READ
0
How to biophysically constrain the flu virus (1)
4 MIN READ
0
Subatomic: From thermophiles to humans (3)
3 MIN READ
0
Cryo-EM: Linking spatial and conformational constraints
9 MIN READ
0
A reversible TCA cycle in a thermophile (3)
4 MIN READ
0
A reversible TCA cycle in a thermophile
5 MIN READ
0
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (4)
8 MIN READ
0
Anti-entropic sunlight: Schrödinger’s Creationist Secret? (3)
6 MIN READ
1
BiondVax Universal Flu Vaccine Patent
4 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (4)
5 MIN READ
0
The MicroRNAome Strikes Back: A Sokalian hoax (2)
6 MIN READ
0
A mental health problem at the highest level (2)
3 MIN READ
0
Diet-driven RNA interference and cancer prevention (3)
6 MIN READ
0
Enzyme-constrained interethnic diversity (8)
< 1 MIN READ
0
Enzyme-constrained interethnic diversity (7)
6 MIN READ
0
Diet-driven RNA interference and cancer prevention
5 MIN READ
0
Enzyme-constrained interethnic biodiversity (1)
5 MIN READ
0
Quantized energy-dependent viral trophism (2)
2 MIN READ
0
A Mathematical Model Links Quantum Physics to Quantum Souls (2)
4 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls (4)
11 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls (2)
3 MIN READ
0
The “walking fish” walks straight from quantum physics to quantum souls
6 MIN READ
0
From base editing to RNA editing (6)
8 MIN READ
0
Who created your virus-driven death gene? (3)
3 MIN READ
0
Energy-dependent base editing and correction of mutations (3)
3 MIN READ
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (3)
3 MIN READ
0
Kinetically Stable Thermodynamically Activated Cell Metabolism (2)
4 MIN READ
0
The tipping point (revisited): 68,000 publications
5 MIN READ
0
Trump challenges the CDC to remember 9/11
14 MIN READ
0
Narcissistic egomaniacal and deadly denial of autophagy
6 MIN READ
0
Elsevier fails to support the concept of autophagy
4 MIN READ
0
From Autophagy.pro (transitions)
4 MIN READ
0
Nature vs Science and Autophagy.pro
7 MIN READ
0
The overwhelming ignorance of sex researchers (2)
4 MIN READ
0
Energy-dependent base editing and correction of mutations (2)
9 MIN READ
0
Trashing the 2nd Law
7 MIN READ
0
The overwhelming ignorance of sex researchers
5 MIN READ
0
Mouse morphs and primate diversity in 50 years
7 MIN READ
0
Who created your virus-driven death gene? (1)
5 MIN READ
0
MicroRNAs and the Cassandra syndrome (revisited)
4 MIN READ
0
Light-activated error free DNA repair
5 MIN READ
0
Eutrophication and phosphorylated biodiversity
6 MIN READ
0
Alternative splicing: a new therapy?
3 MIN READ
0
Selfish X-linked alleles and X chromosome inactivation
3 MIN READ
0
Pheromones biophysically constrain RNA-mediated biodiversity (1)
5 MIN READ
0
Pheromones biophysically constrain base editing and RNA editing
3 MIN READ
0
From base editing to RNA editing (5)
< 1 MIN READ
0
From base editing to RNA editing (4)
5 MIN READ
0
The next reformation: 500 years too late? (1)
< 1 MIN READ
0
The next reformation: 500 years too late? (2)
2 MIN READ
0
The next reformation: 500 years too late? (3)
5 MIN READ
0
From base editing to RNA editing (2)
7 MIN READ
0
From base editing to RNA editing
2 MIN READ
0
Cryo-EM: More than a suggestion
< 1 MIN READ
0
Long-term adaptation replaces evolution (3)
6 MIN READ
0
Long-term adaptation replaces evolution (2)
2 MIN READ
0
Exome Sequencing Impact in Routine Care
4 MIN READ
0
Virulence: Out of stock
2 MIN READ
0
Cryo-EM from atoms to ecosystems
6 MIN READ
0
Entertaining yourself to death
6 MIN READ
0
Criticisms of a validated model
9 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (3)
2 MIN READ
0
Predicting who wins the 2017 Nobel Prizes (2)
4 MIN READ
0
Predicting who wins the 2017 Nobel Prizes
4 MIN READ
0
1996-2016: Ignoring alternative splicings of pre-mRNA
7 MIN READ
0
Life and death via chemical effects on photosynthesis
8 MIN READ
0
Inventing “Transcriptome Trajectory Turning Points”
2 MIN READ
0
Methylation and the Innate Immune System
< 1 MIN READ
0
The billion dollar baby (revisited)
3 MIN READ
0
Sexual communication signals: New Insights!
10 MIN READ
0
An alternative mode of bacterial quorum sensing?
3 MIN READ
0
Stem cells do not create themselves
3 MIN READ
0
Pseudoscientists hate what science explains! (3)
4 MIN READ
0
Robert Sapolsky’s legacy of atheistic pseudoscientific nonsense
4 MIN READ
0
The Origin of Information (4)
4 MIN READ
0
Measuring energy vs human idiocy (social science)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (8)
5 MIN READ
0
Energy-dependent physical and biophysical constraints (6)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (5)
7 MIN READ
0
Energy-dependent physical and biophysical constraints (3)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (2)
4 MIN READ
0
Energy-dependent physical and biophysical constraints (1)
5 MIN READ
0
God’s shrinking role in salvation (3)
9 MIN READ
0
God's shrinking role in salvation (3)
9 MIN READ
0
MicroRNAs GnRH and the failure of sex research
7 MIN READ
0
God’s shrinking role in salvation (2)
5 MIN READ
0
God’s shrinking role in salvation
8 MIN READ
0
Hard Science vs the neo-Darwinian “magic box”
9 MIN READ
0
Infections and age change the odor of wine and people
4 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (2)
6 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models
7 MIN READ
0
Food energy-dependent epigenetic adaptation (2)
< 1 MIN READ
0
Food energy-dependent epigenetic adaptation
11 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (6)
8 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (5)
4 MIN READ
0
Energy as information and constrained endogenous RNA interference (4)
7 MIN READ
0
Energy-dependent microRNA biogenesis
4 MIN READ
0
Feng Zhang refutes theistic evolution
4 MIN READ
0
Open Science: Closed to facts about microRNAs
6 MIN READ
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3 MIN READ
0
Respiration-dependent endogenous RNA interference
4 MIN READ
0
Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution
3 MIN READ
0
Synthetic RNA-based switches
2 MIN READ
0
Cytosis: Biology Content
7 MIN READ
0
Light-activated feedback loops vs self-organization of ecosystems
7 MIN READ
0
Cytosis: A Cell Biology Board Game
< 1 MIN READ
0
Proof: Sunlight is energy as information
< 1 MIN READ
0
The essence of precision medicine: drug targets or healthy longevity?
4 MIN READ
0
The essence of precision medicine
4 MIN READ
0
Allen Institute confirms food energy is information
6 MIN READ
0
RNA-mediated adult learning, memory, and neurogenesis
3 MIN READ
0
Energy-dependent allelic imbalances, viruses, and pathology
3 MIN READ
0
Theistic evolutionists fight back and lose (3)
4 MIN READ
0
Theistic evolutionists fight back and lose (2)
4 MIN READ
0
Young earth creationists refute theistic evolution
3 MIN READ
0
Charles Darwin refutes theistic evolution
2 MIN READ
0
Bill Gates refutes theistic evolution (prequel)
2 MIN READ
0
Bill Gates refutes theistic evolution (sequel)
8 MIN READ
0
Bill Gates refutes theistic evolution
4 MIN READ
0
Wikipedia refutes theistic evolution
4 MIN READ
0
Pseudoscientists fail to refute theistic evolution
4 MIN READ
0
Francis S. Collins refutes theistic evolution
6 MIN READ
0
Energy is information. Objections over ruled. You’re fired!
7 MIN READ
0
Happy Darwin Day (2017)
4 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science (2)
3 MIN READ
0
Physicists: Desperate Acts (revisited)
6 MIN READ
0
Energy as information and constrained endogenous RNA interference (2)
2 MIN READ
0
Virus-driven energy theft and premature death
3 MIN READ
0
Dobzhansky 1973 and precision medicine (5)
3 MIN READ
0
Dobzhansky 1973 and Precision Medicine (2)
5 MIN READ
0
Trump’s appeal to common sense (2)
3 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Twisted theories and weaponized facts
3 MIN READ
0
Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.
6 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Science journalists or paid propagandists? (3)
6 MIN READ
0
Chirality is reality
6 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
Vietnam Veterans and others with glioblastoma
3 MIN READ
0
Energy-dependent sensory maps (1996-2016)
5 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016
12 MIN READ
0
Energy-dependent oscillating gene networks organize life
4 MIN READ
0
2016 obfuscated facts about energy as information
5 MIN READ
0
Re-inventing mutation-driven evolution (2)
4 MIN READ
0
Re-inventing mutation-driven evolution
3 MIN READ
0
Bird-brained theorists
< 1 MIN READ
0
Autophagy is the antiphage defense strategy
3 MIN READ
0
Energy-dependent de novo creation and neurogenesis (2)
5 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Politicized science: The demise of RNA-mediated.com?
3 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Phylogenetic similarity sans energy
2 MIN READ
0
Light, behavior and autophagy, a gender-specific risk factor
4 MIN READ
0
Controlled amino acid treatment of all pathology
4 MIN READ
0
Energy-dependent purifying selection / autophagy (2)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (4)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (6)
3 MIN READ
0
Survivors of RNA-mediated terrorism
5 MIN READ
0
RNA-mediated “repurposing” is autophagy
2 MIN READ
0
RNA-mediated "repurposing" is autophagy
2 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (8)
4 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Virus-driven mutation or amino acid substitution
5 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (7)
3 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (2)
2 MIN READ
0
From Precis to Proof in 6000 years (3)
2 MIN READ
0
From Precis to Proof in 6000 years (2)
5 MIN READ
0
Top-down adaptation vs bottom-up evolution
6 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution (3)
< 1 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
80 years of causal analysis (1936 – 2016)
11 MIN READ
0
Did evolution autophosphorylate your kinases? (3)
2 MIN READ
1
Pheromone-controlled autophagy
4 MIN READ
0
Virus-mediated hecatombic evolution
2 MIN READ
0
Did evolution autophosphorylate your kinases? (2)
5 MIN READ
1
Nutrient-dependent autophagy
3 MIN READ
0
Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (3)
3 MIN READ
0
The last RNA-mediated theory killer
< 1 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
A working model of “captured” genes
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
Plant microRNAs slow virus-driven aging
3 MIN READ
0
Increased soil pH and nutrient availability
4 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Virus-driven energy theft: honeybee model
3 MIN READ
0
Antithetical conclusions (7)
3 MIN READ
0
Antithetical conclusions (4)
3 MIN READ
0
Anthetical conclusions (2)
5 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Pseudoscientists ignore what serious scientists prove
6 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (3)
< 1 MIN READ
0
Biophysically constrained cell type differentiation
3 MIN READ
0
From angstroms to ecosystems
7 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Q and A: Energy-dependent cell type differentiation
10 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
Did “Nature” kill Steve Jobs?
3 MIN READ
0
Virus-driven downsizing of the human brain
2 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
RNA methylation (2)
7 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
RNA methylation
2 MIN READ
0
Energy-dependent RNA methylation (9)
2 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (4)
5 MIN READ
0
Secular humanism and ecoterrorism
4 MIN READ
0
Magic, Miracle, or Molecular Mechanism (2)
8 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (5)
6 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
MicroRNAs and/or QTLs: Who buried what?
2 MIN READ
0
Wasted Templeton Funding (3)
2 MIN READ
0
Millions of water molecules vs years of evolution
2 MIN READ
0
Molecular Diagnostics: What is unprotected life (4)
2 MIN READ
0
Genome-gate: Follow the money?
4 MIN READ
0
Molecular Diagnostics: What is unprotected life? (2)
7 MIN READ
0
Ricki Lewis’ Time Machine (4)
8 MIN READ
0
Creating and/or programming the immune system
< 1 MIN READ
0
Half truths support theories without facts
4 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Energy-dependent purpose vs teleophobic telorexia
12 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Do not miss the misrepresentations
2 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Energy dependent RNA-mediated immunity (4)
6 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
Energy dependent RNA-mediated immunity (2)
10 MIN READ
0
Energy-dependent RNA-mediated immunity (1)
10 MIN READ
0
Science vs semantics
4 MIN READ
0
From angstroms to ecosystems and entropy
2 MIN READ
0
Bacteria see the light and they adapt (2)
5 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA
2 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (7)
5 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
The Light and Darkness of “Evolution 2.0”
11 MIN READ
0
Will modern human populations adapt to the Zika virus?
5 MIN READ
0
Models of scientific literacy
3 MIN READ
0
Organic Compounds and the Miracle of Smell and Taste
7 MIN READ
0
Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
0
Ricki Lewis’ Time Machine (2)
6 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Virus-perturbed alternative splicings
3 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
Origin and evolution of the genetic code
2 MIN READ
0
The unoffically uninvited
3 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
Stress-induced energy-dependent DNA repair
4 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
MicroRNA-mediated RNA epigenetics
2 MIN READ
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Epigenetic (re)programming of behavior (3)
5 MIN READ
0
Perry Marshall: too much information for atheist PZ Myers
3 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Neo-Darwinian sink testing
2 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
RNA-mediated theory killers (6) (7) (8) (9) (10)
5 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (4)
9 MIN READ
0
Essential pseudoscientific concepts of atheism
3 MIN READ
0
RNA-mediated theory killers (2)
8 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
MicroRNAs vs Red Queen hypothesis
4 MIN READ
0
Neo-Darwinism vs the neocortex
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Life and death predicted by DNA methylation
3 MIN READ
0
Stress-perturbed mitochondrial dysfunction (2)
5 MIN READ
0
Behavioral Immune System model
4 MIN READ
0
Understanding cell type differentiation
3 MIN READ
0
Let there be anti-entropic light (3)
6 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Neuroplasticity
4 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Models are not theories (2)
2 MIN READ
0
MicroRNA-encoded behavior
7 MIN READ
0
Fossils vs cell types and the brain
3 MIN READ
0
Can veterans and other prisoners escape pseudoscience?
2 MIN READ
0
eQTLs and ecological adaptation
< 1 MIN READ
0
Unraveling the secrets of RNA-mediated events
2 MIN READ
0
RNA central and RNA-mediated.com
6 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Human pheromone deniers: What’s next?
5 MIN READ
0
700 million years of evolution?
5 MIN READ
0
Biophysically constrained or unconstrained?
2 MIN READ
0
Mutated mitochondrial genes vs Supercoiled DNA
2 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Mystery machine vs medical intelligence
2 MIN READ
0
Preventing genomic entropy
4 MIN READ
0
Energy and evolution: another opinion?
2 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Microbes to humans 2015 Nobel Prize
2 MIN READ
0
Non-mainstream scientist shares Nobel prize in Medicine
3 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Viruses come alive: Tree of life pseudoscience
6 MIN READ
0
Theorists have not seen the light (2)
3 MIN READ
0
Gene creation (revisited)
2 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
A Darwinian pediatrician and expected life span
2 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Pathology: Eating and breathing viruses
2 MIN READ
0
Exosomes and the RNA-mediated future of medicine
5 MIN READ
0
Somatic hypermutation vs RNA-mediated events
2 MIN READ
0
Phytochemical link from the sun to cell types
2 MIN READ
0
Genome sequencing, cadherins, and quantum consciousness
6 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
Thermotolerance and Longevity
57 MIN READ
0
Is life the balance between quantum and classical physics?
3 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Atomic-resolution of cell type signaling
4 MIN READ
0
Information and communication (2)
6 MIN READ
0
Information and communication
2 MIN READ
0
Eibi Nevo gets it wrong
3 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
Olfaction & the octopus and human genomes
3 MIN READ
0
Thermodynamic constraints did not evolve
3 MIN READ
0
Protosuns, prebiotic molecules, proteins, and people
4 MIN READ
0
Mammalian-wide interspersed repeats (MIRs)
2 MIN READ
0
Ecological speciation vs revised evolutionary syntheses
6 MIN READ
0
Ecology replaces the extended evolutionary synthesis
4 MIN READ
0
The stability of organized genomes (4)
3 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Epimutation.com: a domain of confusion
8 MIN READ
0
Light -induced nucleic acid-mediated gene duplication?
< 1 MIN READ
0
Is the best Chinese research from China?
3 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
RNA-mediated terms of virus-induced en-deer-ment
2 MIN READ
0
Domestication via a single amino acid substitution
2 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Is photic-zone ribosomal diversity linked to all biodiversity?
2 MIN READ
0
Picornaviruses moving between primates (or not)
2 MIN READ
0
Riding the wrong direction
3 MIN READ
0
Faithfully repaired DNA
5 MIN READ
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
MicroRNA – controlled ecological adaptations
5 MIN READ
0
Becoming biologically informed
2 MIN READ
0
Celebrating independence from ridiculous theories
3 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
The sum of our RNA-mediated parts
2 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Iron, ferritin, thyroxine
2 MIN READ
0
Virus-driven death by evolutionary theory
3 MIN READ
0
“Evolution” of sex differences?
2 MIN READ
0
Nutrient stress-induced RNA-mediated pathology
< 1 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
What I cannot create I eliminate from discussion
3 MIN READ
0
Healthy mutants
2 MIN READ
0
Uniquely epigenomic gene regulation
2 MIN READ
0
Living the life that randomness created? (Sarcasm alert)
3 MIN READ
0
Unknown mechanisms and conclusions
2 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Physicians who practice evolutionary medicine?
3 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
Appetite for ingesting theories (raw)
< 1 MIN READ
0
I forgot. How do mutations cause evolution?
4 MIN READ
0
One amino acid substitution, genes, and brain activity
3 MIN READ
0
Batch effect vs epigenetic effects
3 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Bee-birthed epigenetics and primate cell types
5 MIN READ
0
Scientists lose. A sci-fi author gains credibility
2 MIN READ
0
Vitamin B3 and DNA repair
4 MIN READ
0
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
The microbiome, pharmacogenetics, and privacy
< 1 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Protein isoforms do not evolve
3 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
Chance mutations — not natural selection
5 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
Physics, chemistry, light, and life
2 MIN READ
0
MicroRNAs and the exposome
5 MIN READ
0
Epigenetics vs the fossil record
4 MIN READ
0
An epigenetic mark links algae, worms, and flies
2 MIN READ
0
Effect and affect of a single base-pair change
4 MIN READ
0
Thermodynamics and protein folding landscapes
2 MIN READ
0
RNA-mediated silencing of a chromosome
3 MIN READ
0
Feedback loops link insects to human brains
2 MIN READ
0
Viruses and cell type differentiation
3 MIN READ
0
RNA-mediated cell types and precision medicine
5 MIN READ
0
DNA Methylation and organized genomes
7 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
Amino acid-dependent cell type differentiation
8 MIN READ
0
Nutrient-dependent RNA interference (2)
4 MIN READ
0
Mutisensory integration: watching the paradigm shift
12 MIN READ
0
Origin of life and cancer (1,2,3)
2 MIN READ
0
Silencing genes and serious scientists
3 MIN READ
0
The miRNA/mRNA balance: a suboptimal strategy?
2 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
Life: conserved ion and amino acid transporters
3 MIN READ
0
Too many targets for theories
3 MIN READ
0
Creating nothing but a theory (3)
4 MIN READ
3
Creating nothing but a theory (2)
4 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
Viruses and ecologically adapted animals
2 MIN READ
0
2 genes in 2 species (too expensive and too insignificant)
11 MIN READ
0
The quantum / classical RNA-mediated ‘tipping point’
3 MIN READ
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Correctly modeling biological energy
2 MIN READ
0
Questions about life’s diversity
21 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
Walk towards the light
< 1 MIN READ
0
Epigenetics Skeptism
5 MIN READ
0
Is DNA-directed transcription RNA-mediated?
2 MIN READ
0
What about birds?
5 MIN READ
0
RNA directed DNA methylation and cell types
4 MIN READ
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2 MIN READ
0
Reverse phosphorylation
7 MIN READ
0
RNA-mediated repurposing in microbes and adaptations in primate brains
2 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
An epigenetic trap (the prequel)
5 MIN READ
0
Imagining that data historically supports evolutionary theory
7 MIN READ
0
The anti-entropic force of "Nature"
2 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
Military combat training to fight disease (2)
3 MIN READ
0
Atoms to ecosystems is not almost a molecular ecology
3 MIN READ
0
Epigenetic effects of viruses on cellular homeostasis (2)
2 MIN READ
0
RNA-mediated epigenetic modification via DNA-methylation
4 MIN READ
0
How fast can evolutionary theory be changed?
5 MIN READ
0
Biological energy and a microbiome model of a light-driven time machine
3 MIN READ
0
Quantum Superpositions: let there be light
4 MIN READ
0
Are viruses microRNAs? (2)
5 MIN READ
0
Sneaking up from behind
4 MIN READ
0
Beneficial microbes kill beneficial mutations
4 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
A single amino acid substitution differentiates cell types of E. coli
3 MIN READ
0
Unconstrained evolutionary innovability
4 MIN READ
0
Mutagenesis: Replacing facts with theories
5 MIN READ
0
ISHE's human ethology group
2 MIN READ
0
From Hydra to humans vs a Lakatosian research program
4 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
The future of physics predicts no future for evolutionary theory
3 MIN READ
0
Model organisms: the birds and the bees
3 MIN READ
0
Chemical ecology and RNA-mediated control of DNA loops
< 1 MIN READ
0
Atoms to ecosystems: Evolutionary theory vs the coelacanth
6 MIN READ
0
Jumping back: Science or Pseudoscience? (2)
2 MIN READ
0
Jumping back: Science or Pseudoscience?
6 MIN READ
0
Single-cell level assay of protein biosynthesis and degradation
2 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
Epigenetic pharmacology and RNA-mediated transciptional landscapes
3 MIN READ
0
RNA-mediated events and "The Theory of Everything"
4 MIN READ
0
RNA-mediated species specificity
2 MIN READ
0
Are mutations beneficial?
4 MIN READ
0
The key to science: experimental evidence
5 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
0
More than a bag of chemicals?
2 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
Making sense of quotes scattered across disciplines
2 MIN READ
0
Intelligent viruses and cancers?
10 MIN READ
0
Complex behaviors of cell types in cancer
6 MIN READ
0
De novo DNA methylation?
3 MIN READ
0
RNA eclipses the importance of DNA to cell type differentiation
4 MIN READ
0
Pharmacogenomics
3 MIN READ
0
Sexual differentiation of cell types in plants
2 MIN READ
0
A model of MHC 'evolution'
2 MIN READ
0
From deep time into real time: What evolutionary processes?
10 MIN READ
0
In theory, or supported by experimental evidence?
5 MIN READ
0
It’s cell type differention, not cell fate determination (2)
3 MIN READ
0
Are evolutionary theorists 'nob ends'?
5 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
Nutrient-dependent gene duplication in plants (but not animals?)
4 MIN READ
0
No understanding of biodiversity
2 MIN READ
0
Behavioral ecology: please continue to believe in our fantasies
3 MIN READ
0
RNA-mediated genetic engineering (Part 3)
< 1 MIN READ
0
RNA-mediated genetic engineering (Part 2)
3 MIN READ
0
RNA-mediated genetic engineering
2 MIN READ
0
Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
0
RNA-mediated cell type differentiation and behavior
3 MIN READ
0
Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
Ecological variation and niche construction: 1, 2, 3
6 MIN READ
0
Stop evolutionary theorists. Kill cancers
3 MIN READ
0
De novo gene Creation sans evolution of genes via mutations
4 MIN READ
0
Seemingly futile cycles are not thermodynamically futile
3 MIN READ
0
Memory of repression and memory of behavior
2 MIN READ
0
Genotype, observed phenotype, and distinctly disordered behaviors
3 MIN READ
0
RNA-mediated ecological adaptation is not evolution
2 MIN READ
0
Exploding genomes and chromosomal rearrangements via RNA-mediated events
2 MIN READ
0
Behavior (2): All responses are RNA-mediated not genetically-determined
4 MIN READ
0
A relatively young branch of science called epigenetics
4 MIN READ
0
Insect homology and diversity attributed to mutations
2 MIN READ
0
Baby talk: More misrepresentations of ecological adaptations
2 MIN READ
0
Comparing divergent model organisms
2 MIN READ
1
Epimutations: Attacking pseudoscientific dogmas
4 MIN READ
0
Order and disorder: Ecological adaptations not mutations
6 MIN READ
0
microRNAs and species relationships
3 MIN READ
0
The quantum biology of consciousness
3 MIN READ
0
Ecologically linked adapted ants and brains
2 MIN READ
0
Cell-type differentiation
2 MIN READ
0
The wrong picture of our evolution
4 MIN READ
0
96 fixed amino acid substitutions, not 96 genes
6 MIN READ
0
Alternative splicings (very technical)
2 MIN READ
0
Social experiences epigenetically effect gene networks
2 MIN READ
0
Pheromone-controlled thermodynamics and cancer
2 MIN READ
0
Pheromones and cancer
4 MIN READ
0
Honeybees, food odors, and perfume
< 1 MIN READ
0