Bruce McEwen’s legacy: sympatric speciation (5)
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Looking for refutations of pseudoscientific nonsense touted by evolutionary biologists and Big Bang cosmologists? See how light-activated microRNA biogenesis is linked to human biodiversity via microbiome-associated studies and human skin phenotypes.
Extracellular vesicles released by melanocytes after UVA irradiation promote intercellular signaling via miR21 1/7/20
The growth pattern of Angel Trumpets helped me to link Rosalind Franklin’s work on the tobacco mosaic virus from light-activated microRNA biogenesis in plants to examples of how extracellular vesicles, also known as exosomes are linked to the prevention of all diseases.Exosomes are membrane bound extracellular vesicles (EVs) that are produced in the endosomal compartment of most eukaryotic cells.HERV-K HML-2 diversity among humans was linked to biophysically constrained viral latency across kingdoms (4/8/16) and “…no infectivity was detectable due to a single amino acid substitution…” (12/29/08). Rather than admit to this decades-old example of light-activated biogenesis and energy-dependent ecological adaptations via fixation of many different RNA-mediated amino acid substitutions in species from microbes to humans, Jack Lenz concluded that “…somehow HML-2 was active in the human lineage for 13 million years… ” (4/19/16)about the evolution of amino acids. Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution 11/22/13
Koel et al. (p. 976) show that major antigenic change can be caused by single amino acid substitutions.
Link the pseudoscientific nonsense about the evolution of amino acid composition in proteins and the evolution of amino acid substitutions in the influenza viruses to facts about biophysically constrained major antigenic changes and food energy-dependent pheromone-controlled ecological adaptations via Dobzhansky (1964) and Dobzhansky (1973)
For example, the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla.
Admit that McEwen et al, (1964) linked God’s Creation of sunlight and water to all oxygen-dependent biophysically constrained viral latency and healthy longevity across kingdoms via this claim, which was clearly linked to sympatric speciation via the synthesis of RNA:
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
Join intelligent serious scientists who are “Combating Evolution to Fight Disease ,” or they will continue to ridicule you and all other biologically uninformed theorists.VIDEO The Existence of Nothing (2013) and how it was linked to the evolution of everything in the BioMed Central Special Issue In the Light of Evolution from 12/23/16 to 12/5/19Splendor and misery of adaptation, or the importance of neutral null for understanding evolution 12/23/16Examining non-LTR retrotransposons in the context of the evolving primate brain 8/11/17The human microbiome in evolution 12/27/17Nothing in cancer makes sense except… 2/21/18Special Issue, see the US patent for the microRNA-mediated prevention and/or effective treatment of all cancers. It was issued on 12/25/18.Methods and compositions for identifying a peptide having an intermolecular interaction with a target of interest Proof of concept ”Special Issue from BioMed Central to present the established facts.Feedback loops link odor and pheromone signaling with reproduction 11/18/05Biology could be so much more 11/22/19
The organism has several systems in place—including the neuroendocrine, metabolic, and immune systems—that normally help us adapt to new situations. It’s when these systems become overused or dysfunctional that the mind and body begin to wear and tear.
The virus-driven degradation of messenger RNA has been linked from failed ecological adaptations to all the wear and tear. The light-activated assembly of the microRNA-RNA-peptide nanocomplex has been linked from the physiology of reproduction to healthy longevity via our visual perception of energy and mass in the context of the space-time continuum.Olfaction Warps Visual Time Perception 3/17/17Evolution rising from the grave 3/2/2000 and Living with the Neanderthals 8/14/2003Dobzhansky (1973) claimed to be an evolutionist to ensure a successful career in academia.
…the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla (p. 127).
More than 1800 human hemoglobin variants have since been linked to the diversity of populations in every ecological niche that humans have constructed during the past 5-10,000 years.HbVar: A Database of Human Hemoglobin Variants and Thalassemias Past 5,000 years prolific for changes to human genome 11/28/12
The findings confirm their earlier work suggesting that the majority of variants, including potentially harmful ones, were picked up during the past 5,000–10,000 years.
All the variants are biophysically constrained by the prevention of diseases found in non-human primates such as:Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk 4/23/18Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18,Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems .
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0
Energy-dependent maternal-to-zygotic transition
6
1
Epigenetically effected energy-dependent fluorescence
5
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1
0
Nutrient-dependent autophagy
3
0
Nutrient-dependent pheromone-controlled autophagy (2)
6
0
Nutrient-dependent pheromone-controlled autophagy
3
0
Life is energy-dependent task management
3
0
Hypothesis free pseudoscience vs facts (4)
5
0
Base pairs, olfaction and RNA thermometers
4
0
Chromatin: The structure of DNA
6
0
Consciousness is simply food rearranged
2
0
Light energy-dependent active motifs
6
0
Light energy-induced base pair changes (2)
4
0
Light energy-induced base pair changes (1)
6
0
Linking RNA structure to function
3
0
Exosomes, Inflammatory Disease, Pathogenesis, Treatment
< 1
0
How did the innate immune system evolve?
4
0
The Aquatic Ape: New evidence?
4
0
Increased soil pH and nutrient availability
4
0
Virus-driven energy theft: honeybee model
3
0
Pseudoscientists ignore what serious scientists prove
6
0
GC-rich neo-Darwinian train wreck
5
0
Biophysically constrained cell type differentiation
3
0
Food supplement or licensed immunostimulant?
6
0
Virus-driven downsizing of the human brain
2
0
The Mind’s Eyes (revisited)
10
0
Energy-dependent RNA methylation (4)
5
0
Energy-dependent RNA methylation (1)
6
0
Secular humanism and ecoterrorism
4
0
War Games: False Flag Terrorism
5
0
Energy-dependent biodiversity (3)
7
0
Magic, Miracle, or Molecular Mechanism (2)
8
0
Energy-dependent creation and entropy
4
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5
0
RNA-mediated physics, chemistry, and molecular epigenetics (2)
7
0
RNA-mediated physics, chemistry, and molecular epigenetics
9
0
Wasted Templeton Funding (3)
2
0
Millions of water molecules vs years of evolution
2
0
A bumper crop of virus-infected weeds and people
2
0
Magic, Miracle, or Molecular Mechanism?
10
0
Molecular Diagnostics: What is unprotected life? (5)
5
0
Molecular Diagnostics: What is unprotected life? (2)
7
0
Molecular Diagnostics: What is unprotected life?
2
0
Ricki Lewis’ Time Machine (4)
8
0
Confusing effects and affects of visual input
2
0
Selective reporting of inferences: examples of pseudoscience
14
0
Energy-dependent purpose vs teleophobic telorexia
12
0
Stress-linked population-level history dependence
5
0
Energy dependent RNA-mediated immunity (6)
5
0
Do not miss the misrepresentations
2
0
Energy dependent RNA-mediated immunity (2)
10
0
Energy-dependent RNA-mediated immunity (1)
10
0
Bacteria see the light and they adapt (2)
5
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9
0
Nutrient-dependent RNA-mediated cause and effect
3
0
Hydrogen-atom transfer in DNA base pairs (7)
5
0
Bacteria see the light and they adapt
7
0
Models of scientific literacy
3
0
Cancer: Evolution 2.0’s Blind Spot
13
0
Despicable fools?
4
0
Ricki Lewis’ Time Machine (2)
6
0
The radical pair mechanism of ecological speciation
3
0
Hydrogen-Atom Transfer in DNA Base Pairs (4)
4
0
Blood test links atoms to ecosystems
2
0
Stress-induced energy-dependent DNA repair
4
0
Teleophobes vs teleophiles: a recent history
2
0
Amino acid substitutions, stress, and human behavior
3
0
Finding peace and π in the light of H bond energy (2)
8
0
Finding peace and π in the light of H bond energy
5
0
Epigenetic (re)programming of behavior (3)
5
0
Assumptions prove ignorance
5
0
NORAD: air defense and defense against genomic entropy
7
0
Manufacturing fossil “evidence”
4
0
RNA-mediated theory killers (4)
9
0
Essential pseudoscientific concepts of atheism
3
0
Natural cooperation and Evolution 2.0
6
0
A two-faced protein enables RNA-mediated DNA repair (4)
6
0
A two-faced protein enables RNA-mediated DNA repair (5)
4
0
Teaching the biologically uninformed
3
0
Hydrogen-Atom Transfer in DNA Base Pairs
9
0
Sulfated steroids and RNA-mediated identity codes
< 1
0
The Sherlock lab: Beneficial mutations
5
0
A two-faced protein enables RNA-mediated DNA repair
2
0
Nutrient-dependent trophic analogs
3
0
Plasma created by sunlight and RNA–mediated epigenetic heredity
2
0
Positive feedback loops and epigenetic traps
2
0
Behavioral Immune System model
4
0
Let there be anti-entropic light (3)
6
0
Theorists can’t understand biology
6
0
Cell type differentiation: atoms to ecosystems
2
0
Models are not theories (3)
3
0
More re-evolved functional structures?
2
0
Rediscovering quantum behavior
2
0
From dust to genomic entropy?
3
0
Models are not theories (2)
2
0
Can veterans and other prisoners escape pseudoscience?
2
0
Cyclic cosmology and the stability of organized genomes
4
0
RNA central and RNA-mediated.com
6
0
Ecological speciation. Get it, theorists?
< 1
0
Skip the politics; embrace the facts
5
0
Controled Stem Cell Expansion
3
0
Human pheromone deniers: What’s next?
5
0
700 million years of evolution?
5
0
Biophysically constrained or unconstrained?
2
0
RNA-mediated retrotransposon-mediated biodiversity
3
0
Mystery machine vs model (2)
2
0
Mystery machine vs medical intelligence
2
0
Epigenetic inheritance of stress-perturbed protein folding
2
0
Preventing genomic entropy
4
0
Checkpoint checkmate: viruses lose if conditions of life win
< 1
0
Molecule of life vs animal experiments
< 1
0
Supercoiled DNA constrains virus-driven genomic entropy
2
0
Let there be anti-entropic light (2)
4
0
Foundamentals of theory
4
0
Microbes to humans 2015 Nobel Prize
2
0
Is mainstream science in “Science” pseudoscience?
5
0
Mechanisms of stress: from genes to cancer
9
0
Gene creation (revisited)
2
0
Hijacked light energy and vertebrate pathology
4
0
Theorists have not seen the light
4
0
A Darwinian pediatrician and expected life span
2
0
A 5-10K comparison of design principles to evolution
3
0
Alternative pre-mRNA splicing and ecological adaptation
7
0
Pathology: Eating and breathing viruses
2
0
Exosomes and the RNA-mediated future of medicine (3)
2
0
Exosomes and the RNA-mediated future of medicine (2)
< 1
0
Exosomes and the RNA-mediated future of medicine
5
0
Multi-omic analysis features (SNPs, miRNA)
3
0
Anti-entropic effects on the origin of life
< 1
0
Somatic hypermutation vs RNA-mediated events
2
0
Phytochemical link from the sun to cell types
2
0
New anti-entropic microbes
3
0
Metabolic competition and cancer
2
0
Natural selection: an anti-entropic force?
2
0
Genome sequencing, cadherins, and quantum consciousness
6
0
“New” quantum biology. Pirating the old
3
0
Cell types, SNVs, CNVs, and chromosomes
3
0
Is life the balance between quantum and classical physics?
3
0
Anti-entropic containment of energy: symbiosis 1.0
5
0
The “great filter” is an epigenetic trap
4
0
Information and communication
2
0
Unraveling evolutionary pseudoscience
2
0
The stability of organized genomes (3)
3
0
Viruses, amino acids, and somatic cell types (3)
9
0
Viruses, amino acids, and somatic cell types (2)
5
0
Becoming biologically informed (3)
3
0
Easy editing: Reinventing our RNA world
3
0
Riding the wrong direction
3
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6
0
MicroRNA – controlled ecological adaptations
5
0
Is SUMOylation RNA-directed DNA methylation? (revisited)
4
0
“New” epigenetic mechanism for lifelong learning?
3
0
Protein folding and Google page rank
2
0
Iron, ferritin, thyroxine
2
0
“First” evidence
5
0
RNA-mediated development
2
0
Creating and maintaining the human virome
2
0
Alternative splicings: epigenetics meets pharmacogenomics
4
0
Epigenetic regulation of aging by glycine and GnRH
5
0
Pattern recognition: biogeochemical structure and function
5
0
Viruses and the human-like microbiome
3
0
Informing the biologically uninformed
< 1
0
Batch effect vs epigenetic effects
3
0
Vitamin B3 and DNA repair
4
0
Bees and primates automagically evolve
3
0
Ignoring systems complexity (it’s too complicated)
3
0
Five years of Ferguson
2
0
Virus-driven cancer treatment and prevention
2
0
The microbiome, pharmacogenetics, and privacy
< 1
0
A special issue on nutritional epigenetics
5
0
Retinoic acid + one receptor regulate the genome
3
0
Epigenetics: microRNAs effect an integrative pathway
4
0
Protein isoforms do not evolve
3
0
From gut bacteria to breast milk and back
5
0
Viruses in gut microbes
4
0
MicroRNAs and the exposome
5
0
Epigenetics vs the fossil record
4
0
Thermodynamics and protein folding landscapes
2
0
RNA-mediated silencing of a chromosome
3
0
Feedback loops link insects to human brains
2
0
DNA Methylation and organized genomes
7
0
Mutisensory integration: watching the paradigm shift
12
0
Nutrient-dependent microRNAs control cell types
6
0
Too many targets for theories
3
0
Methylation maintains cell type differences (2)
2
0
Creating nothing but a theory (3)
4
3
Creating nothing but a theory
4
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4
0
Correctly modeling ecological adaptation
4
0
Questions about life’s diversity
21
0
Luis P. Villarreal tells it like it is
3
0
Epigenetics Skeptism
5
0
Is DNA-directed transcription RNA-mediated?
2
0
What about birds?
5
0
Implicating microRNAs in cancer
2
0
Reverse phosphorylation
7
0
Theoretical physics and molecular biology
5
0
Atoms to ecosystems is not almost a molecular ecology
3
0
Epigenetic effects of viruses on cellular homeostasis (2)
2
0
Quantum physics, quantum biology, and quantum consciousness
4
0
How fast can evolutionary theory be changed?
5
0
Constrained evolution is ecological adaptation
5
0
Unified nutritional and molecular mechanisms
9
0
Removing natural selection; reshaping the horse; adjusting evolutionary theory
4
0
Models by evolutionary biologists are not models
2
0
Are mutations beneficial?
4
0
Nothing new under the sun, except pseudoscientific nonsense
6
0
In theory, or supported by experimental evidence?
5
0
Evolutionary theorists justify fear of the Ebola viruses
2
0
Understanding physical forces of ecological variation and adaptation
< 1
0
RNA-mediated genetic engineering (Part 3)
< 1
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2
0
Different physical locations and different molecular mechanisms of health and disease
2
0
Physics, Chemistry, and Molecular biology (PCMb)
2
0
Ecological variation and niche construction: 1, 2, 3
6
0
RNA-directed DNA methylation and RNA-mediated events
5
1
Seemingly futile cycles are not thermodynamically futile
3
0
Memory of repression and memory of behavior (2)
< 1
0
Mechanisms that are not understood increase clarity
4
2
microRNAs and species relationships
3
0
Genes and Race: Human History?
2
0
MiRNAs methylation and ecological adaptation sans mutations
2
0
Not focused and self-aggrandizing
2
0
Cell-type differentiation
2
0
(click to enlarge)