MicroRNA-mediated healthy longevity (2)

By: James V. Kohl | Published on: January 10, 2020

MicroRNA-mediated healthy longevity (1)
More than 1000 new published works that mention ‘microRNA’ are added each month.
Meanwhile, the mass media market on Facebook caters to those who ignore what is known to all serious scientists about biophysically constrained viral latency, and presents reports that are virtually meaningless to scientific advances in healthcare.
For comparison to the life’s works of Bruce S. McEwen on energy-dependent biophysically constrained viral latency, “…cells increase in number in the aging brain, and are induced by viral infections and simulated stroke [hypoxia].”
See: WHO says mysterious illness in China likely being caused by new virus

“Coronaviruses are a large family of viruses that range from the common cold to SARS. Some cause less-severe disease, some more severe. Some transmit easily from person to person, while others don’t,” the WHO statement said.

An international study discovers a new origin of lymphatic vessels in the heart

…opens the way to future research into the mechanism underlying lymphatic vasculogenesis in this new niche…

All niche construction is energy-dependent and microRNA-mediated, which means there is no new origin of anything under the sun. God’s Creation of sunlight has already has been linked from the hydrophobicity of supercoiled DNA to biophysically constrained viral latency or to virus-driven pathology.

Biologists identify pathways that extend lifespan by 500% 1/9/20

The identification was reported in a journal article published on 7/23/19. This model organism exemplifies nutrient-dependent pheromone-controlled sympatric speciation, not the widely reported millions of years it supposedly took for C. elegans to evolve into P. pacificus, a predatory nematode with ‘teeth.’

What is known to all intelligent serious scientists about energy-dependent microRNA-mediated biophysically constrained viral latency and sympatric speciation takes a bite out of neo-Darwinian theories and Big Bang cosmology. The Big Bite kills Big Bang theories and all other theories.

See for instance: “Orca grandmothers babysit young whales, study finds

Save the whales and save us all. Stop the theorists who continue to tout their pseudoscientific nonsense. With help from George M. Church of course.

See also: The predictive power of the microbiome exceeds that of genome-wide association studies in the discrimination of complex human disease (1/2/20)

Naturally occurring RNA interference could save us all, and George Church is the first person listed on the patent, which was reported to be a “billion dollar baby” in therapy.

Who gets to pay the billions?

Genetic testing provides insights to sudden unexplained deaths in Amish community

Each had the same homozygous multiexon duplication in RYR2, as did multiple distantly related relatives who also experienced a sudden cardiac arrest during exercise.

The duplications are food energy-dependent and typically prevented by the physiology of reproduction across generations. This disease process could be traced from one base pair change to the virus-driven failed fixation of one microRNA-mediated amino acid substitution, which could be corrected with nutritional therapy.

Follow the money to see how long it takes someone besides George M. Church and others to report that fact.
Comments like that got me put in Facebook jail, so that others won’t see them. If my Facebook account is suspended, you may never learn the truth about what is known to all serious scientists.

In fighting gut infections, nervous system is key, team finds

…scientists at Yale and Harvard medical schools have discovered that, in response to bacterial invaders, nerve cells within the intestine—and not immune cells or cells lining the intestinal wall—release infection-fighting cytokines. They report their findings Jan. 9 in the journal Cell.

Psoriasis: Towards a novel therapeutic approach

…demonstrates the essential role of Flt1 and Nrp1 expression in the skin epidermis to mediate psoriasis development. The results of this study have important implications for the understanding of mechanisms leading to psoriasis, one of the most frequent inflammatory diseases, and for the treatment of patients with psoriasis.”

Treatment with virus-killing UV light or with DHEA (in Europe) have been effective for decades in patients with psoriasis.

Healthy habits in middle age linked to longer life free from disease

Who didn’t know that?

Tea drinkers live longer


An out-of-the-box attack on diabetes

When the researchers measured levels of GDF15 in pancreas tissue from people with diabetes, they found the protein was depleted in their malfunctioning islet cells.

What caused the virus-driven protein depletion? Was it caused by viruses?

Missing protein in brain causes behaviors mirroring autism

Where do missing proteins go after the virus-driven degradation of messenger RNA links failed DNA repair to all pathology?

The ‘airbag’ that protects cells against stress

Mechanosensing is microRNA-mediated.
See: MicroRNA-365 functions as a mechanosensitive microRNA to inhibit end plate chondrocyte degeneration by targeting histone deacetylase 4.

Persistence of gut microbial strains in twins, living apart after cohabitating for decades

This is expected for in all Microbiome-Association Studies of transgenerational epigenetic effects on morphological and behavioral phenotypes that pseudoscientists use Genome-Wide Association Studies to try to explain.

Eight deaths in Germany blamed on shrew-borne disease

Carried by the bicoloured white-toothed shrew, the virus triggers an inflammation of the brain, and is known to affect horses and sheep.

The researchers speculated that it could be transmitted by house cats that had come into contact with infected shrews.

Research in mice shows antibodies derived from mom’s gut microbes protect newborns from E. coli infection

…antibodies made in response to one particular organism in the maternal gut are passed on to the offspring both via milk and through the placenta to protect newborn pups from infection

How dying cells prevent dangerous immune reactions

A key link in the dectin-1 signaling pathway is the enzyme NADPH oxidase 2.

…the scientists needed an animal—with all the diversity of the various components of the immune system—to demonstrate that the bond between these two proteins actually suppresses autoimmune reactions.

The bonds between proteins are energy-dependent and microRNA-mediated. Viruses break the bonds.

Disorderly DNA helps cancer cells evade treatment

…cancer cells with disordered packing are more likely to adapt to and evade treatments…

The virus-driven breaking of hydrogen bonds and degradation of messenger RNA causes the ‘disordered packing.’  Nutrient stress and social stress contribute to the adaptations of viruses in pathological cell types.

Could pancreatitis be a stress hormone deficiency?

Pancreatitis exemplifies a stress-linked virus-driven disease.

Plant-derived SVC112 hits cancer stem cells, leaves healthy cells alone

Early drug development undertaken outside the funding structure of established pharmaceutical sponsors often requires contributions from many sources, and the current project is no exception…

That’s why funding ploys like this are used to give investors the hope that they can make money on a cure.
Three US patents for biophysically constrained viral latency and effective cancer treatment or prevention have already been issued.  The cure links the light-activated assembly of the microRNA-RNA-peptide nanocomplex to healthy longevity via everything known to serious scientists. A few of them have told investors the truth, but most are still trying to get more funding.

Neurons’ energy organelle protected from damage linked to ALS, Alzheimer’s

“It hasn’t yet been emphasized in the search for effective therapeutics, but mitochondrial failure is a feature of many neurodegenerative disorders and something that must be corrected if neurons are to survive,” says principal investigator Ronald Davis, Ph.D., professor in the Department of Neuroscience at Scripps Research. “So I’m a big believer that finding mitochondria-protecting molecules is the way to go against these diseases.”

From CRISPR Multiplexing to Pleistocene Park

The discussion questions were tailored to avoid representations of facts.
George M. Church linked God’s Creation of sunlight and water to naturally occurring light-activated carbon fixation and the ATP-dependent creation of RNA via oxygen-dependent biophysically constrained viral latency. The details are in McEwen at al., (1964)
55 years later George M. Church has linked McEwen’s history of published works to the prevention of all diseases via RNA interference via the patent for RNA-guided human engineering.
To his credit, I do not think that George M. Church has ever lied about what he has done. But few people are likely to pin him down on the difference between alternative splicings of RNA and nonhomologous end-joining. His commercial interests may not be perfectly clear until that happens, or until the theoretical nonsense is exposed on January 10, 2020.

See also:

In season three of Missing Links, host Gregg Braden presents the scientific research that reveals the divine matrix, an infinite universal energy field

There are no missing links if you believe that the food organisms eat links the physiology of reproduction to biophysically constrained viral latency and sympatric speciation during the past 5-10,000 years. You must invent missing links to believe in natural selection for mutations and evolution.
See this report from the “Nature Publications Group,” and prepare for others to announce the microRNA/RNA-mediated cure for all virus-driven pathology: It’s ATP-dependent RNA interference, and the cure has been patented by at least 3 different groups.
The findings confirm their earlier work suggesting that the majority of variants, including potentially harmful ones, were picked up during the past 5,000–10,000 years.

Summary: It is useless for me to compete against the amount of pseudoscientific nonsense and fake news that most people are subjected to see each day.

The pseudoscience and fake news keeps them dumbed-down and much easier to manipulate as they suffer unnecessarily and die prematurely from the viruses that are killing us all.

They need only follow the extant literature as it is added to the PubMed database each day. See: MicroRNA

Pseudoscientists are not going to help you avoid the consequences of your ignorance, and most serious scientists know better than to try to educate the biologically uninformed who prefer pseudoscience to facts about healthy longevity.

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