The tipping point (revisited): 100K (3)

By: James V. Kohl | Published on: April 3, 2020

More than 100,000 indexed published works that mention microRNAs link the Creation of anti-entropic virucial light from light-activated microRNA biogenesis to RNA-mediated autophagy via the physiology of reproduction and biophysically constrained viral latency in all living genera.
See for review: The tipping point (revisited): 100K (1) at
See for review: The tipping point (revisited): 100K (2) at
Moving forward to what is known about how microRNAs are linked from RNAs to healthy longevity see: Autophagy regulation by microRNAs: Novel insights into osteosarcoma therapy 3/31/20

…microRNAs (miRNAs) can modulate autophagy.

…miRNAs can use inhibiting or promoting autophagy agents. The present review summarizes the effects of aberrant expression of miRNAs in OS diagnosis and treatment with focus on their roles in autophagy.

The US patent for the microRNA-mediated cure of all cancers via autophagy was issued on 12/25/18.
See: Methods and compositions for identifying a peptide having an intermolecular interaction with a target of interest 
See also the: Proof of concept
The proof of concept links the pheromone-controlled physiology of reproduction in bacteria to biophysically constrained RNA-mediated protein folding chemistry via natural selection for what organisms eat, even in organisms that eat electrons and produce Uranium ores.
See for example: Biogenic non-crystalline U(IV) revealed as major component in uranium ore deposits 6/1/17
Ecological variation has been linked to ecological adaptations at every level of investigation by intelligent serious scientists. Indeed, the fact that pheromones control genetic processes in mice was linked to the likelihood that they control genetic processes in humans in 1994.
See: [Pheromonal regulation of genetic processes: research on the house mouse (Mus musculus L.)]

A study of the influence of pheromone stressor(s) on proliferating germ and somatic cells was performed on laboratory lines of house mouse in the context of the physiological hypothesis of mutation process, proposed by M.E. Lobashev in 1947. Data from experiments are presented, and results obtained during last 10-15 years are discussed. The adaptive role of cytogenetic and other observed pheromonal effects is considered. The possible existence of interorganism systems of genetic regulation is discussed, the search for and study of which may help in more complete understanding of the regularities of functioning of genetic material.

Pseudoscientists  have continued to tout ridiculous theories about mutations during billions of years. They refuse to tether their claims to experimental evidence of top-down causation that begins with God’s Creation of sunlight and water, despite the fact that that everything learned by serious scientists since 1964 attests to the facts about the ATP-dependent creation of RNA.
See: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” 

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

For comparison, see: The origins of quantum biology (12/12/18)

What remains indisputable is that the quantum dynamics that are undoubtedly taking place within living systems have been subject to 3.5 billion years of optimizing evolution. It is likely that, in that time, life has learned to manipulate quantum systems to its advantage in ways that we do not yet fully understand. They may have had to wait many decades, but the quantum pioneers were indeed right to be excited about the future of quantum biology.

Reported as: The real history of quantum biology

Quantum biology seeks to understand whether quantum mechanics plays a role in biological processes. Recent research has already shown phenomena such as photosynthesis, respiration, bird navigation and even the way we think are all influenced by quantum mechanics.

See also: A high-throughput platform for feedback-controlled directed evolution 4/2/20

We use this platform to characterize the evolutionary stochasticity of T7 RNA polymerase evolution…

The fact that energy is required to create the enzymes such as RNA polymerase is removed by the claim about evolutionary stochasticity. There is no such thing.
All serious scientists have linked quantum coherence to coherently organized biology via the Creation of sunlight and water, which has been linked to the creation of all oxygen-dependent biodiversity on Earth.
I should not need to repeatedly cite:
MicroRNAs organize intrinsic variation into stem cell states 3/5/20 and MicroRNA Involvement in Signaling Pathways During Viral Infection 3/10/20 because the facts that link quantum coherence to coherently organized biology via protection from viruses are perfectly clear to all intelligent serious scientists.
But, see for comparison: Lies to children 4/2/20 by Philip C. Ball

Ernest Rutherford’s solar-system atom or Gilbert Lewis’ octet-rule atom are examples, and in fact chemistry might be more replete with them than other sciences – think of those unrealistically neat divisions into ionic and covalent bonding, or how oxidation states are first explained.

What did you learn, and when did you learn about ionic and covalent bonding, or how oxidative phosphorylation biophysically constrains viral latency?
See: McEwen et al., (1964) Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

I learned about biophysically constrained RNA interference from my mentor, Bruce S. McEwen
See for comparison this interview from 6/24/17 for my comments on Philip C. Ball’s “Santa Claus” theory of the Universe.


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