FDA’s ignorance: From roots to shoots (2)

By: James V. Kohl | Published on: April 6, 2020

Quantum coherence is linked to coherently organized biology in a well-ordered Universe, which is what happened in two recent publications.
MicroRNAs organize intrinsic variation into stem cell states 3/5/20
MicroRNA Involvement in Signaling Pathways During Viral Infection 3/10/20
See also: FDA’s ignorance: From roots to shoots (1) 3/9/20

‘Everything depends on where you got virus’: US & Russian top specialists explain odds of catching Covid-19 & surviving 3/8/20

 “We are aware of at least 40 coronaviruses”

One amino acid substitution in the influenza virus caused a change in virulence.  “Koel et al. (p. 976) show that major antigenic change can be caused by single amino acid substitutions.”

If sensitivity and specificity are not sufficient to differentiate between strains of coronaviruses, no intelligent person will know what the test results mean.

Abbott touts speed, scale of POC coronavirus test 3/30/20

Abbott did not share figures on the sensitivity or specificity of the test.

President Donald Trump highlighted the Abbott test during a briefing Sunday, saying it signals “a whole new ballgame” in U.S. testing of coronavirus. Former FDA Commissioner Scott Gottlieb, who’s routinely called for wider scale testing, also heralded the development.

The “whole new ballgame” is the one in which obfuscation of facts about how energy-dependent changes in microRNA-mediated amino acid substitutions link RNA interference to the prevention of all virus-driven diseases. It’s the same game as it has always been. Follow the money!

See the patent for RNA-Guided Human Genome Engineering reported as: Get Well in the RNAi Way-RNAi, A Billion Dollar Baby in Therapy 3/3/16

5. Repetitive elements or endogenous viral elements can be targeted with engineered Cas+gRNA systems in microbes, plants, animals, or human cells to reduce deleterious transposition or to aid in sequencing or other analytic genomic/transcriptomic/proteomic/diagnostic tools (in which nearly identical copies can be problematic).

We now have: Clues to COVID-19 coronavirus’s vulnerability emerge from an antibody against SARS 4/3/20

…the antibody’s binding site is highly similar between the two coronaviruses—differing by just four…amino-acids. That high degree of similarity implies that the site has an important function that would be lost if it mutated significantly.

Mutated binding sites have always linked failed RNA-directed DNA repair to all virus driven pathology via repetitive elements or endogenous viral elements, which can be targeted with a change in diet. The change in diet is linked linked to a change in the production of species-specific pheromones that biophysically constrain viral latency across kingdoms via fixation of amino acid substitutions.

See: [Pheromonal regulation of genetic processes: research on the house mouse (Mus musculus L.)] (1994)

A study of the influence of pheromone stressor(s) on proliferating germ and somatic cells was performed on laboratory lines of house mouse in the context of the physiological hypothesis of mutation process, proposed by M.E. Lobashev in 1947. Data from experiments are presented, and results obtained during last 10-15 years are discussed. The adaptive role of cytogenetic and other observed pheromonal effects is considered. The possible existence of interorganism systems of genetic regulation is discussed, the search for and study of which may help in more complete understanding of the regularities of functioning of genetic material.

Ask the current director of the FDA, Dr. Stephen M. Hahn about that fact. What has he learned since 1947 about how to prevent the mutations that link virus-driven pathology to all diseases?

For comparisons, see: Eukaryotic plankton diversity in the sunlit ocean (2015)

[Light activated] Diversity emerged at all taxonomic levels, both within the groups comprising the ~11,200 cataloged morphospecies of eukaryotic plankton and among twice as many other deep-branching lineages of unappreciated importance in plankton ecology studies.


Virus-mediated archaeal hecatomb in the deep seafloor (2016)

We show here for the first time the crucial role of viruses in controlling archaeal dynamics and therefore the functioning of deep-sea ecosystems, and suggest that virus-archaea interactions play a central role in global biogeochemical cycles.

See also: Forty years with coronaviruses 3/30/20

She avoids linking more than 100,213 published works on microRNAs to the cure for coronavirus / Covid19 pathology via use of the term “subgenomic RNAs,” which she links to viral evolution and interspecies infections.

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