The tipping point (revisited): 101K (1)

By: James V. Kohl | Published on: April 22, 2020

The tipping point (revisited): 100K (1) 3/30/20

4/22/20 update: Items: 1 to 20 of 101001

More than 101,000 indexed publications that mention “microRNA” link virus-driven changes in base pairs from microRNA-150-5p downregulation of long non-coding RNA MALAT1 to acute respiratory distress syndrome by upregulating ICAM-1 expression.
See: Long non-coding RNA MALAT1 exacerbates acute respiratory distress syndrome by upregulating ICAM-1 expression via microRNA-150-5p downregulation 4/21/20

These findings demonstrated that MALAT1 silencing can potentially suppress HPMEC apoptosis and alleviate lung injury in ARDS via miR-150-5p-targeted ICAM-1, suggestive of a novel therapeutic target for ARDS.

Intelligent people with common sense may think the dose of the influenza virus vaccine for ages 65+ is causing most of the deaths attributed to COVID-19 via the reassembly of viruses and viral fragments reported as Viruses Can Scatter Their Genes Among Cells and Reassemble 5/21/19
The intelligent people with common sense can join the serious scientists who have ridiculed all theorists, and the so called ‘experts’ who learned almost nothing about energy-dependent RNA-mediated cell type differentiation since 2014. Here’s a clue: Cell type differentiation requires energy-dependent changes in base pairs.
See also: MALAT1 silencing Items: 1 to 20 of 134
For ridicule of biologically uninformed science idiots and others with no common sense, see:

See also: What is Life?: With Mind and Matter and Autobiographical Sketches (Canto Classics) Reprint Edition

…the extremely well-ordered state of matter…return[ed for the use of plants]. (These, of course, have their most power supply of ‘negative entropy’ the sunlight.)

See also:

The anti-entropic force of virucidal ultraviolet light links guanine–cytosine (G⋅C) Watson–Crick base pairing from hydrogen-atom transfer in DNA base pairs in solution to supercoiled DNA, which protects the organized genomes…

See also:

Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics to food energy-dependent pheromone-controlled coherently organized biology.


See also: Nuclear hubs built on RNAs and clustered organization of the genome 4/4/20

NEAT1 and NEAT2/MALAT1 exemplify long non-coding RNAs (lncRNAs) known to function in nuclear bodies; however, we suggest that RNA biogenesis itself may underpin much nuclear compartmentalization.

My summary: Light-activated microRNA biogenesis and the assembly of the microRNA-RNA-peptide nanocomplex,  is required for ATP-dependent RNA synthesis and the growth of plants. Plant growth supplies food energy via ingestion of plant and animal proteins. That fact was linked to neo-Darwnian pseudoscientific nonsense about evolved biodiversity via their ‘karyotype to hub’ hypothesis.
For more pseudoscientific nonsense see: Evolution Promotes Mothers Who Tend, So Daughters Can Befriend 10/2/19
I saw this posted to The Robert Sapolsky Fan Club Facebook Group and wrote:

Thanks. This is proof that social science (aka pseudoscientific nonsense) will prevail among the members of this group who continue to believe in ridiculous theories rather than accept the facts from current research like this:

I provided the link to Long non-coding RNA MALAT1 exacerbates acute respiratory distress syndrome by upregulating ICAM-1 expression via microRNA-150-5p downregulation 4/21/20

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