The microRNA-mediated future of humanity (4)

By: James V. Kohl | Published on: April 30, 2020

(click to enlarge)

The microRNA-mediated future of humanity (3)

Trump touts study on sunlight to kill coronavirus, but official warns against Americans changing behavior 4/23/20

The updated report on 4/24/20 appeared as: Medical experts rip Trump’s suggestion that sunlight, disinfectants may treat coronavirus

Dr. Jesse Goodman, the former Chief Scientist of the FDA and now a Georgetown University professor and attending physician, told USA TODAY the amount of heat and light needed to kill the virus would be harmful to cells within the body and was “not something we now have evidence to support.”

He was, of course, lying.

See: UV-Induced Charge Transfer States in DNA Promote Sequence Selective Self-Repair (1/13/16)

The authors linked the involvement of two bases to a long-living charge transfer state between G and A that appears to be responsible for the repair.

That is what Dr. Jesse Goodman claimed we did not have evidence to support.

The supporting evidence was linked to claims made by 2016 Chemistry Nobel Laureate, Bernard Feringa in:

This Nobel Laureate also placed his claims into the context of Biblical Creation via this quote:

Disabled were walking again, the blind were seeing again, and the death rose from the grave. 2013 was the year in which prophesy from the bible became reality.

Moving forward towards the scientific creationist’s approach, the light-activated assembly of the microRNA-RNA-peptide nanocomplex was linked to the treatment of coronavirus-linked pathology via the energy-dependent Creation of an anti-viral enzyme, called RNA polymerase.

See: Remdesivir is a direct-acting antiviral that inhibits RNA-dependent RNA polymerase from severe acute respiratory syndrome coronavirus 2 with high potency 4/13/20

For a historical perspective on the energy-dependent RNA-mediated Creation of enzymes, receptors, and all other proteins, see: McEwen et al. (1964): Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”

The authors clearly stated:

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

Fifty-five years later, God’s Creation of sunlight and water and the link to the ATP-dependent creation of the RNA-dependent anti-viral RNA polymerase were reported in the context of this news feature:

See: To counter the pandemic, clinicians bank on repurposed drugs 4/29/20

The host–virus interactions that Krogan’s lab identified offer up clues as to why this new coronavirus causes symptoms that range from diarrhea and an inability to smell, to pneumonia and fatal multiorgan failure. “Other coronaviruses are similar but not as virulent,” Krogan says. “In terms of protein interactions, this virus seems to hijack and rewire so many different cellular pathways—it gets its fingers into all the key machinery of a cell.”

All host-virus interactions are biophysically constrained by the light-activated energy-dependent Calvin Cycle, which regulates the key machinery of all cells.

Every living thing on Earth depends on the Calvin cycle.
The Calvin cycle has four main steps: carbon fixation, reduction phase, carbohydrate formation, and regeneration phase. Energy to fuel chemical reactions in this sugar-generating process is provided by ATP and NADPH, chemical compounds which contain the energy plants have captured from sunlight.

My Conclusion:

Remdesivar is a repurposed drug that links God’s Creation of anti-entropic virucidal light to an effective treatment for coronavirus pathology via speculation in What is life? (1944) and this brief review of top-down causation.

This presentation on Precision Medicine from 3/30/16 links nutritional epigenetics to biophysically constrained viral latency across kingdoms via God’s Creation of sunlight, water, and the ATP-dependent RNA-mediated physiology of pheromone-controlled reproduction in species from microbes to humans.

See:

See also: Modern Approaches to Exact Diagonalization and Selected Configuration Interaction with the Adaptive Sampling CI Method
On 3/11/20, President Donald J. Trump’s scientific advisor, KB Whaley linked God’s Creation of subatomic particles from His Creation of sunlight and water to a simulation of 34 electrons in 152 orbitals via exact diagonalization and selected configuration interaction, which biophysically constrains viral latency and every aspect of coherently organized microRNA-mediated biology.
The levels of complexity can be examined by ages 10-14+ via game-play of:
Subatomic
Periodic
Cytosis
Virus Expansion
and
Ecosystem
With the availability of Genotype (October 2020) everyone on Earth can see that after three generations of light-activated biophysically constrained plant growth, neo-Darwinian theorists and Big Bang cosmologists lose because no experimental evidence of top-down causation links God’s Creation of energy as information from the physiology of reproduction to the mutation-driven evolution of anything except more diseases!
See:

See also:

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro 2/4/20

The in vitro / test tube chemistry of biophysically constrained protein folding chemistry has been linked from viral latency to healthy longevity in species from microbes to humans via the physiology of reproduction and Biblical Genesis.

Unfortunately, most people cannot learn that fact from social media.

For example, see: ‘Expert Twitter’ Only Goes So Far. Bring Back Blogs 4/23/20

Twitter was optimized for links and short musings. It’s not well suited for complex discussions or nuanced analyses. As a result, the feeds of these newly emerged pandemic experts are often a messy jumble of re-ups, unrolled threads, and screenshot excerpts of articles.

After nearly 30,000 Tweets, I learned that Twitter’s follower count metric is used to quantify the astounding rate at which previously unknown experts have exploded into prominence. But,

There are also issues with consolidating all of this information on the servers of a small number of commercial companies granted the ability to censor posts without accountability or transparency.

For example, Facebook blocks any mention of my domain microRNA.pro, no matter who mentions it. Today, Facebook started blocking my mention of Autophagy.pro
I do not know if Twitter is doing anything to block the dissemination of accurate information from my domains, but the metrics on my account went from ~750,000 impressions in 28 days to 228,000 -despite an increase in the number of people viewing my profile, which increased by 33.8% to 3385 during the past 28 day.
One reason for Facebook to block me from linking to my domains and for Twitter to manipulate the number of people who see my Tweets may be the fact that that the future of humanity has always been food energy-dependent and microRNA-mediated. If people are convinced that our future is linked from mutations in viruses to evolution, the vaccine industry and the drug developers can continue to make billions of dollars in profits as billions of people suffer unnecessarily and die prematurely.
This, despite the patented cure for all virus-driven diseases, which is naturally occurring light-activated carbon fixation and RNA interference.
See: RNA-Guided Human Genome Engineering

5. Repetitive elements or endogenous viral elements can be targeted with engineered Cas+gRNA systems in microbes, plants, animals, or human cells to reduce deleterious transposition or to aid in sequencing or other analytic genomic/transcriptomic/proteomic/diagnostic tools (in which nearly identical copies can be problematic).