pH-dependent viral latency (4)

By: James V. Kohl | Published on: May 29, 2020

My top tweet @microRNApro during the month of March 2018 earned 3,884 impressions.
I wrote:

See also my series on “Interethnic biodiversity” via this search: Interethnic genetic simiarities and a PubMed search for microRNA

See also: Denying Genetics Isn’t Shutting Down Racism, It’s Fueling It 3/30/18

On the male-female divide, for example, Reich cites profound differences, “reflecting more than 100 million years of evolution and adaptation.” On race, he is both agnostic about what we will eventually find out with respect to the scale of genetic differences, and also insistent that genetic differences do exist: “You will sometimes hear that any biological differences among populations are likely to be small, because humans have diverged too recently from common ancestors for substantial differences to have arisen under the pressure of natural selection. This is not true.

Neo-Darwinian evolutionary theorists are not known for telling the truth about the difference between evolution and adaptation. They have only their ridiculous theories to use in attempts to explain similarities and differences between sexes and races.
But Reich revealed the truth (above). No experimental evidence of top-down food energy-dependent causation has bee linked to 100 million years of evolution. All experimental evidence of top-down causation links biophysically constrained viral latency from the physiology of pheromone-controlled reproduction to food energy-dependent ecological adaptations during the past 5-10,000 years.
See for instance: Base-pair conformational switch modulates miR-34a targeting of Sirt1 mRNA 5/27/20
They linked energy-dependent changes from angstroms to ecosystems in all living genera via the physiology of reproduction.

Moving forward, George M. Church, who co-owns the patent for naturally occurring energy-dependent RNA interference has since collaborated with scientific creationists in South Korea to publish:
Korean Genome Project: 1094 Korean personal genomes with clinical information 5/27/20, which was reported as:
Korean Genome Project data released for public use 5/28/20

…over 70 percent of the doubletons or singletons that have been identified thus far have never been reported before—and fewer than 20 percent of them were designated as common. They also found that there were more deletions than insertions in the indels, suggesting possible skewing of variant calling. They conclude their remarks by suggesting that the dataset should provide a strong reference panel going forward, thereby enhancing personalized medical applications for the people of Korea.

The dataset links God’s Creation of UV light and water to biophysically constrained viral latency across kingdoms via oxidative phosphorylation. That explains this announcement:
NIH releases strategic plan to accelerate nutrition research over next 10 years 5/27/20, which was reported as:

NIH, guided by its Nutrition Research Task Force (NRTF) and armed with the insights from the nutrition science community, practitioners, the public, and others, has created a bold vision to advance nutrition science discoveries over the next 10 years. With a focus on precision nutrition, the plan reflects the wide range of nutrition research supported across NIH – over $1.9 billion in fiscal year 2019. The strategic plan calls for a multidisciplinary approach through expanded collaboration across NIH Institutes and Centers to accelerate nutrition science and uncover the role of human nutrition in improving public health and reducing disease.

See for comparison my LabRoots virtual conference presentation on Precision Medicine (2/15/17).

Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics to chemistry/chirality and to molecular epigenetics/autophagy.

The National Microbiome Initiative links microbial quorum sensing to the physiology of reproduction via endogenous RNA interference and chromosomal rearrangements. The rearrangements link energy-dependent fixed amino acid substitutions to the Precision Medicine Initiative via genome wide inferences of natural selection.

This detailed representation of energy-dependent natural selection for codon optimality links biologically- based cause and effect from G protein-coupled receptors to RNA-mediated amino acid substitutions and the functional structure of supercoiled DNA. Energy-dependent polycombic ecological adaptations are manifested in supercoiled DNA. Chromosomal inheritance links the adaptations from morphological phenotypes to healthy longevity via behavioral phenotypes.

For contrast, virus-driven energy theft is the link from messenger RNA degradation to negative supercoiling, constraint breaking mutations, and hecatombic evolution. The viral hecatomb links transgenerational epigenetic inheritance from archaea to Zika virus-damaged DNA, which typically is repaired by endogenous RNA interference and fixation of RNA-mediated amino acid substitutions in organized genomes.

George M. Church and Francis S. Collins are among many others who must now face the consequences of their ignorance and/or deceptions.
See: A Quick HYL1-Dependent Reactivation of MicroRNA Production Is Required for a Proper Developmental Response after Extended Periods of Light Deprivation 7/18/18

“…plants alter microRNA (miRNA) biogenesis in response to light transition.

Ages 10+ can now link God’s Creation of subatomic particles to biophysically constrained viral latency in all genotypes via game-play.
Virus Expansion
Genotype (October 2020)

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