From optoribogenetics to HelioRiboGenetics (1)

By: James V. Kohl | Published on: October 5, 2020

Optoribogenetic control of regulatory RNA molecules 9/24/20

“Opto” means light. “Helio” links God’s Creation of UV light to RNA-mediated protection from viruses across kingdoms via hydrogen-atom transfer in DNA base pairs in solution.

Had he lived, Bruce S. McEwen probably would have received the 2020 Nobel Prize in Physiology or Medicine for linking God’s Creation of UV light and water from energy-as-information to biophysically constrained viral latency across kingdoms.

McEwen et al., (1964) linked that heliocentric approach to scientific creationism in Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

Historical perspective: Heliocentrism

…a mathematical model of a heliocentric system was presented, by the Renaissance mathematician, astronomer, and Catholic cleric Nicolaus Copernicus, leading to the Copernican Revolution. In the following century, Johannes Kepler introduced elliptical orbits, and Galileo Galilei presented supporting observations made using a telescope.

God’s Creation of UV light was subsequently linked to constraints on the formation of new galaxies.

See: A measurement of the z = 0 UV background from Hα fluorescence

Fluorescence was linked to the weekend resurrection of the bacterial flagellum.

Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system

McEwen’s history of published works linked 2016 Nobel Laureate, Berhard Feringa’s claims to the weekend Resurrection of Christ. See:

Disabled were walking again, the blind were seeing again, and the death rose from the grave. 2013 was the year in which prophesy from the bible became reality. — De Correspondent dec 2013

A helioribogenetic approach links God’s Creation of UV light and water from the ATP-dependent Creation of RNA and naturally occurring oxygen-dependent RNA interference to the end of all virus-driven pathology via remdesivir treatment of COVID-19 and this patent:  RNA-Guided Human Genome Engineering.

There is no need to introduce neo-Darwinian pseudoscientific nonsense or Big Bang cosmology.

On 10/5, 10/6 and 10/11, will the Nobel Prizes again link President Donald J. Trump’s claims about UV light from the helioribogenetic approach to his remdesivir treatment via what organisms eat and the pheromone-regulated genetic processes of reproduction in species from microbes to man?

See: Repurposing drugs against the main protease of SARS-CoV-2: mechanism-based insights supported by available laboratory and clinical data

…some of these drugs have the potential to simultaneously modulate the functions of viral proteins and the host response system. Interestingly, many of these identified candidates (12 molecules from workflow-I and several molecules, belonging to the chemical classes of alkaloids, tetracyclines, peptidomimetics, from workflow-II) are suggested to possess anti-viral properties…

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