microRNA-mediated replication cycles (7)

By: James V. Kohl | Published on: July 5, 2021

Infectious Thoughts: Discovering Biology as a Social Science (2021 preprint)

“Regarding the Kohl papers; odors are clearly crucial for social communication and food has been a part of this (as has I think RNA). This is a nice summary. But curiously, he does not mention that if
an individual honey bee feeds outside that of its own communal hive feeding it then becomes recognized as foreign and is killed by the hive. Missing is the concept of group identity. And in humans (and great apes), he does not even mention the big changes that occurred in the VMO organ and its receptors and the corresponding changes to visual identity. Let alone any consideration of a viral role. Doesn’t seem he read my book (but then very few have). Maybe the next generation can be infected by such thinking.  (p. 131)

Wen Zhou read our book The Scent of Eros: Mysteries of Odor in Human Sexuality (1995/2002) and her group published Olfaction Warps Visual Time Perception 3/17/17
They linked God’s Creation of the sun’s anti-entropic virucidal energy and humidity to pH-dependent biophysically constrained viral latency across kingdoms via the pheromone-regulated genetic processes of reproduction in species from cyanobacteria to humans.
The facts link visual perception of mass and energy from the physiology of reproduction to claims from 1679 in Merian’s “The Wondrous Transformation of Caterpillars and their Remarkable Diet of Flowers” and Toll9 from Bombyx mori functions as a pattern recognition receptor that shares features with Toll-like receptor 4 from mammals 5/11/21
Like many evolutionary theorists, Luis P. Villarreal fell behind the facts I published as: “Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems“4/18/18
I included a section on “Kohl’s Laws of Biology.” So far as I know, Villarreal and others like him, have ignored the “Laws of Physics” the “Basic Principles of Chemistry” and conserved molecular mechanisms of ATP-dependent RNA synthesis, which I linked to the answer to Schrodinger’s question: What is life? (1944)

What is life when it is not protected from virus driven entropy (video summary) 3/30/16

Poster: The anti-entropic force of virucidal ultraviolet light links guanine–cytosine (G⋅C) Watson–Crick base pairing from hydrogen-atom transfer in DNA base pairs in solution to supercoiled DNA, which protects the organized genomes of all living genera from virus-driven entropy. For example, protection of DNA from permanent UV damage occurs in the context of photosynthesis and nutrient-dependent RNA-directed DNA methylation, which links RNA-mediated amino acid substitutions to DNA repair. In the context of thermodynamic cycles of protein biosynthesis and degradation, DNA repair enables the de novo creation of G protein coupled receptors (GPCRs). Olfactory receptor genes are GPCRs. The de novo creation of olfactory receptor genes links chemotaxis and phototaxis from foraging behavior to social behavior in species from microbes to humans. Foraging behavior links ecological variation to ecological adaptation in the context of this atoms to ecosystems model of biophysically constrained energy-dependent RNA-mediated protein folding chemistry. Protein folding chemistry links nutrient-dependent microRNAs from microRNA flanking sequences to energy transfer and cell type differentiation in the context of adhesion proteins, and supercoiled DNA that protects all organized genomes from virus-driven entropy.

It has since become perfectly clear that microRNA-mediated replication cycles biophysically constrain viral latency across kingdoms via the physiology of reproduction, which forces people like Luis P. Villarreal to mislead others regarding the importance of “the Kohl papers” compared to the importance of the “Villarreal papers” and the papers published by other theorists.

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