Natural selection for adaptation (1)

By: James V. Kohl | Published on: August 19, 2021

My August 12, 2021 tweet made more than 34,000 impressions. That fact was reported on August 18, 2021 after I publicly complained about the delay in making it my “Top Tweet” for the month.
My complaint was based on the fact that nearly 126,000 citations to published works mention microRNAs. Each of them attests to facts about natural selection for energy-dependent codon optimality.
All intelligent serious scientists know that codon optimality biophysically constrains viral latency and healthy longevity across kingdoms via natural selection, which was designed by God for ecological adaptation. No experimental evidence of biophysically constrained genetic processes suggests that beneficial mutations have been linked to the evolution of new species during the past billions to millions of years.
If you do not believe that the God of Abraham is the Designer of natural selection for ecological adaptions, see: Crosstalk between codon optimality and cis-regulatory elements dictates mRNA stability 1/5/21

Codon optimality, microRNAs, and m6A act in conjunction to regulate gene expression in vertebrates

My summary: Light-activated carbon fixation links mRNA stability to healthy longevity across kingdoms via this patent.
RNA-Guided Human Genome Engineering
Okay, I know what you’re asking. How did anyone patent this naturally occurring process? George M. Church claimed the naturally occurring process was non-obvious. That’s how.
See for comparison: Cyanobacteria Inoculation Improves Soil Stability and Fertility on Different Textured Soils: Gaining Insights for Applicability in Soil Restoration 6/11/18 and

Light-activated carbon fixation did not evolve (5)

See for comparison:

  1. Wars caused by metaphors: 1964
  2. MADS-Box Genes Are Key Components of Genetic Regulatory Networks Involved in Abiotic Stress and Plastic Developmental Responses in Plants 7/10/19
  3. Mitoribosome assembly comes into view 8/11/21

Cryo-EM studies detail how epigenetic effects on the human mitoribosomal large subunit RNA that forms the catalytic core of the ribosome link God’s Creation of sunlight and humidity to pH-dependent RNA interference (RNAi) and health sans use of synthetic mRNA vaccines.
It should come as no surprise to intelligent serious scientists that Visible-Light-Induced Dearomatization of Indoles/Pyrroles with Vinylcyclopropanes: Expedient Synthesis of Structurally Diverse Polycyclic Indolines/Pyrrolines 8/16/21 was reported after this discovery: Study of promising photovoltaic material leads to discovery of a new state of matter 5/26/21
The “new state of matter” was linked to this claim from First passage time properties of miRNA-mediated protein translation 8/14/21

…time-dependent moments have been approximately calculated and the role of miRNAs in determining the First Passage Time (FPT) properties of protein dynamics has been established.

See also: Transfer RNA and Origins of RNA Interference 6/23/21

…the defensive functionality of RNAi and its ability to regulate own mRNAs could have emerged almost simultaneously,

Simultaneous emergence and evolution across billions to millions of years are typically placed into the claims of stupid theorists  who think their mathematical models explain how an explosion in the cosmic void automagically led to all biodiversity on Earth.

This begs the question: Whose works have you been following since 2013 when I published my refutation of all stupid theories based on Learning from Bacteria about Natural Information Processing 10/15/09 before the follow-up MicroRNA-based regulation of epithelial-hybrid-mesenchymal fate determination 10/23/13

See: Nutrient-dependent/pheromone-controlled adaptive evolution: a model 6/14/13

Food odors and pheromones link the honeybee model organism and other invertebrate model organisms to olfaction and odor receptors across species. This link provides ‘… a clear evolutionary trail that can be followed from unicellular organisms to insects to humans’ (Kohl, ).

If you have questions about the differences between facts and theories, ask for clarification by Fauci, who claimed it was molecularly impossible to genetically engineer the SARS-CoV-2 virus – despite facts about the clear evolutionary trail linked to all pathology via the Virus-mediated archaeal hecatomb in the deep seafloor 10/12/16.

Do you think Fauci knows nothing about molecular epigenetics, or that he is lying? You have one of two choices.

Ask WHO and the CDC for clarification of facts about DNA N6-methyladenine in mammals in the context of Eukaryotic plankton diversity in the sunlit ocean 5/22/15 and this report of No evidence for DNA N6-methyladenine in mammals 3/18/20
The experimental evidence showed that N6-methyladenine is incorporated into mammalian genome by DNA polymerase six weeks later on 4/30/20

…our data suggest a new origin of DNA N6-methyladenine base in mammals, implicating the complexity of this rare base in the context of genome function.

Thank God, if you had the opportunity to examine the overwhelming complexity of biophysically constrained viral latency and genome function. Thank biologically uninformed theorists and profiteers for the unnecessary suffering and premature deaths caused by SARS-CoV-2 and other viruses, which have been linked to the pathogenesis of all cancers.

See: The regulation of protein translation and its implications for cancer 2/18/21

…modifications of mRNAs mainly N6-methyladenine (m(6)A) modification and noncoding RNAs, such as microRNAs and long noncoding RNAs are involved [in aberrant translation from mRNAs to proteins linked to the pathogenesis of various cancers.]

Thank Eric Lander, President Biden’s science advisor, if you do not believe the facts about RNA interference (RNAi) and biophysically constrained healthy longevity across kingdoms. He presented them in this 2012 special.

What is he claiming now?

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