RNAi 2002 to AI 2021 (1)

By: James V. Kohl | Published on: December 29, 2021

Summary: Intelligent serious scientists have linked energy-dependent RNA interference (RNAi) to all biodiversity on Earth. For comparison, biologically uninformed theorists have nothing but mathematical models and Artificial Intelligence (AI).
Human pheromones: integrating neuroendocrinology and ethology  (2001)

…the affect of pheromones on our emotions is linked to the effect of pheromones on the hormones of the hypothalamic-pituitary-gonadal axis –an unconscious affect. Based upon a detailed mammalian neuroendocrine model, Kohl [15] proposed that LH is the measurable link between sex and the human sense of smell. Kohl [16] detailed reciprocity in olfactory-genetic-neuronal-hormonal-behavioral relationships that appear to link the nature and nurture of human sexuality. Subsequently, Diamond, Binstock, and Kohl [17] offered a more complete overview of nongonadal, nonhormonal, influences on sexual differentiation and of the influence of sensory stimuli, especially chemosensory stimuli, on human sexuality.

Differentiation of all cell types is energy-dependent and microRNA-mediated. That fact means you must start with the potential of hydrogen (pH), and link it to cell type differentiation.
2002 Breakthrough of the Year: Small RNAs

…a class of RNA molecules called small RNAs are actually in charge of many cellular functions. Science hails these discoveries, which are prompting biologists to overhaul their vision of the cell and its evolution, as 2002’s Breakthrough of the Year.

This inhibition, which was later seen in flies and other organisms, came to be known as RNA interference (RNAi). Biologists have come to believe that RNAi protects against harmful DNA or viruses that could disrupt the genome.

2021 Breakthrough of the year Protein structures for all

Work by Anfinsen and others suggested interactions between amino acids pull proteins into their final shapes.

But wait, work by Eugene Koonin’s group suggested that amino acids evolve.
A universal trend of amino acid gain and loss in protein evolution

Amino acid composition of proteins varies substantially between taxa and, thus, can evolve.

Young earth creationists typically do not believe that. See why:

Look over her shoulder:

Growth of Angel Trumpets on the pathway to the Ark Encounter links God’s Creation of sunlight and humidity to all biophysically constrained virus-driven diseases on Earth via the pH-dependent creation of soil types.

The pH-dependent creation of hydrophobic supercoiled DNA links energy-dependent fixation of carbon to RNA-mediated fixation of amino acid substitutions that are required to protect organized genomes of all species on Earth from the virus-driven degradation of messenger RNA (mRNA).

The virus-driven degradation of mRNA links mutations to all virus-driven pathology across kingdoms.  For example, Angel Trumpets are extinct in the wild because their viral load led to an end of their ability to successfully reproduce, unattended.

That fact led the Institute for Creation Research (ICR) to block me from commenting on their Facebook page, and they also blocked me from seeing their tweets on Twitter.

Q: Why would USA-based young earth creationist group block me on social media?
A: Artificial Intelligence (AI) and ICR do not link God’s Creation of hydrogen and facts about hydrogen bonds from energy-dependent changes in single nucleotide polymorphisms (SNPs) in microRNAs to footprints of healthy longevity and all biodiversity at the origin of life 5-10,000 years ago.
Hydrogen bonds are not chemical bonds. They can be easily disrupted but the energy required to restore them links femtosecond blasts of UV light to pH-dependent DNA repair in the context of everything known to intelligent serious scientists about the links from angstroms to ecosystems in all living genera.
See for instance: UV-Induced Charge Transfer States in DNA Promote Sequence Selective Self-Repair 1/13/16. See also Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems  4/18/18 Link Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20 to Peptide synthesis at the origin of life 11/13/20
Note: Peptide synthesis at the origin of life, 5-10,000 years ago has been linked to proton beam therapy for cancer via Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20

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