microRNA-mediated biodiversity (10)
(click to enlarge)@ppchuman, @JikkyKjj, and @B3H3ALTHY are among the anonymous fools, biologically uninformed science idiots, and killer clowns such as @RNAsucks, who failed to link light-activated carbon fixation in cyanobacteria to microRNA-mediated protein folding chemistry and healthy longevity via energy-dependent epigenetic effects on gene sequences and RNA interference (#RNAi), which I detailed in my model.
There is no other model of naturally occurring biophysically constrained pH-dependent viral endemicity for comparison. That fact forced theorists to abandon all past claims about the importance of gene sequencing. After trillions of dollars were spent on useless theories with no explanatory power, they must now attempt to obfuscate cause and effect that clearly links Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20 from Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 to Peptide synthesis at the origin of life11/13/20 and effective treatment of synthetic mRNA-vaccine damage to DNA.
See for example: MiRLoc: predicting miRNA subcellular localization by incorporating miRNA-mRNA interactions and mRNA subcellular localization 2/20/22
MiRLoc uses the functional similarity between miRNAs instead of sequence features and incorporates information about the subcellular localization of the corresponding target mRNAs. The results show that miRNA functional similarity data can be effectively used to predict miRNA subcellular localization, and that inclusion of subcellular localization information of target mRNAs greatly improves prediction performance.
That claim is far from being aligned with data from the Mammarena viruses database, HbVar: A Database of Human Hemoglobin Variants and Thalassemias, which links what is known about light-activated carbon fixation in cyanobacteria to microRNA-mediated protein folding chemistry and relevant clinical variants exeplified in ClinVar.
miRNA functional similarity data cannot replace failed past attempts to link gene-centric theories from gene sequencing to pH-dependent biophysically constrained viral endemicity and healthy longevity. If you believe similarity data can replace facts about microRNA-mediated protein folding chemistry, you are a foolish atheist, Communist, or a stupid conspiracy theorist.
RNA synthesis and genome replication is ATP-dependent in all living species. Viruses steal the energy of ATP for their replication at the cost of healthy longevity across kingdoms.
Alain Kohl’s group has joined others to bring new meaning to the claims about energy-dependent microRNA-mediated protein folding chemistry (and cleavage) in the context of “Kohl’s Laws of Biology.
See: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18.
Biological Laws
Biophysical constraints and biological laws appear to link ecological variation to ecological adaptations via conserved molecular mechanisms in all species. For example, nutrient-dependent ecological niche construction leads to pheromone-controlled social niche construction via the nutrient-dependent pheromone-controlled
physiology of reproduction. The nutrient-dependent origin of amino acid substitutions in viruses [149-152], which also are manifested in plant and animal interactions, exemplifies a continuum of biological plausibility and ecological validity in the context of Laws of Biology.
These Laws of Biology include Kohl’s Laws of Biology, which are so-named because the surname of the first author or sole author on each of 7 peer-reviewed publications in the paragraph below is Kohl. The
Kohls did not create the Laws of Biology; they merely independently incorporated what is known about them into what appears to be a cohesive series of published works.
Kohl’s Laws of Biology
Life is nutrient-dependent. That is a Biological Law. The ecological origin of all biological laws is apparent 1) in the context of systems biology [87]; 2) in the context of the metabolism of nutrients by microbes [153]; and 3) in the context of how the metabolism of nutrients results in species-specific pheromones that control the physiology of reproduction [154]. Taken together, the systems biology of nutrient metabolism to species-specific pheromones, which control the physiology of reproduction, can be expressed in a summary of Kohl’s Laws of Biology:
1) Life is nutrient-dependent. See for review [27,155]. The physiology of reproduction is pheromone-controlled. See for review [26]. In the context of nutrient-dependent epigenetically- effected human reproduction, it is clearer that the epigenetic effects of human pheromones integrate neuroendocrinology and behavior [100], which includes the neuroendocrinology of mammalian behavior associated with the development of sexual preferences [156]. Kohl’s Laws help to explain what was missing from Darwin’s ‘conditions of life.
Light-activated carbon fixation in cyanobacteria has since been linked from microRNA-mediated protein folding chemistry to biophysically constrained biodiversity across kingdoms during the past 6000 years of ecological adaptations.
See also:
Animals’ mitochondria defenses discovered in plants 11/2/17
Mitochondrial metabolite mediates longevity through epigenomes 8/3/20
How metabolic reprogramming in mitochondria promotes or undermines survival and longevity 2/4/22
Atheists in China must try to regain scientific credibility after decades of touting nonsense that has never been supported by facts.
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