RNA-mediated silencing (3)

By: James V. Kohl | Published on: March 18, 2022

Robert H. Singer, co-authored: Single-molecule imaging of microRNA-mediated gene silencing in cells 3/17/22

Simultaneous visualization of single mRNAs, translation, and miRNA-binding revealed that miRNAs preferentially bind to translated mRNAs rather than untranslated mRNAs.

Trust in God, but verify the fact that Singer’s publication history links God’s Creation of anti-entropic virucidal energy to biophysically constrained microRNA-mediated protein folding chemistry and healthy longevity across kingdoms via light-activated carbon fixation in cyanobacteria, and pheromone-regulated genetic processes of preferential binding and reproduction in species from yeasts to humans.
See: Photon-Counting CMOS Sensors Extend Frontiers in Scientific Imaging
See also: MicroRNAs organize intrinsic variation into stem cell states 3/5/20

…naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology.

Link quantum coherence to coherently organized biology via God’s Creation of species-specific cell membranes in this STEM toy for ages 14+: Cellulose
Link quantum biology to effective treatment of cancer via food energy-dependent microRNA abundance compared to virus-driven mutations.
See also: Quantifying the contribution of transcription factor activity, mutations and microRNAs to CD274 expression in cancer patients 3/14/22

…CD274 expression is largely explained by TF activity, and the remaining unexplained cases can largely be explained by mutations or low miRNA abundance.

Low miRNA abundance is caused by the virus-driven degradation of mRNA. Viruses steal the energy that links what organisms eat to microRNA-mediated DNA repair.
Link that fact to effective treatment of cancer via the patent for Methods and compositions for identifying a peptide having an intermolecular interaction with a target of interest 12/25/18

A system of a recombinant bacteriophage library and a target of interest complex, wherein the recombinant bacteriophage peptide library includes a plurality of peptides expressed on the surface of recombinant bacteriophages…

Link bacteriophages to all virus-driven pathology via the degradation of mRNA. Link light-activated microRNA biogenesis from carbon fixation in cyanobacteria to microRNA-mediated protein folding chemistry and healthy longevity via Cellulose: A Plant Cell Biology Game
See examples of COVID-19 linked human idiocy for comparison: A time to reflect 3/10/22

…the virus sequence was swiftly solved, and the spike protein structure emerged.

Spike protein structure did not automagically emerge at the time the virus sequence was solved. Look back at what happened when greedy profiteers corrupted the entirety of the medical-industrial complex via their failure to start with God’s Creation of sunlight and humidity.
On 4/23/20, former President Trump linked it to the end of COVID-19 via what was known to all intelligent serious scientists about physics, chemistry, and molecular interactions across kingdoms in the context of Thomas Hunt Morgan’s 1910 claims about food energy-dependent pheromone- regulated ecological adaptations in Drosophila.
See for review: Genotype (for ages 14+)
See for comparison: Direct observation of adaptive tracking on ecological time scales in Drosophila 3/18/22

Adaptation is a foundational process in evolutionary biology that is central to human health and the conservation of biodiversity. Adaptive tracking, defined as continuous adaptation in response to rapid environmental change, is a potentially critical mechanism by which populations persist in changing environments.

From one week to the next, Science Magazine has pushed the limits of obfuscation to change the definition of evolutionary biology to ecological adaptation.

See for comparison: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18

No one can be forced to apologize for their lack of knowledge, but some stupid theorists could be expected to apologize for their arrogance and ignorance in the context of what has been known for more than 110 years about energy-dependent biophysically constrained microRNA-mediated  species-specific cell type differentiation and Genotypes.

How many theorists failed to  link quantum coherence from coherently organized biology to quantum souls via microRNA-mediated stem cell creation? It is the obvious link to prevention of all virus-driven pathology via observable differences in the growth of Angel Trumpets and successful ecological adaptations in daffodils. Former President Trump announced that fact on 4/23/20 in the context of how sunlight and humidity weaken Covid-19.

Angel Trumpets are extinct in the wild. Daffodils are extremely well adapted. Other organisms and people who are not ecologically adapted suffer unnecessarily and die prematurely from the virus-driven degradation of mRNA.

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