RNA-mediated silencing (9)

By: James V. Kohl | Published on: April 9, 2022

WHO, the World Health Organization, thought you wouldn’t notice that your organizations were infiltrated by entitled feminists and stupid conspiracy theorists. See: Skirting the Matter of Feminism’s Culpability 4/4/22

“…true to feminist form, shifts to men and misogyny the blame for the epistemological collapse occurring in liberal democracies while ignoring the real culprit, feminism.”

See also: RNA-mediated silencing (7)

Three of the 4 articles that linked light-activated carbon fixation in cyanobacteria from microRNA-mediated protein folding chemistry across kingdoms were published on the same day (3/24/22).

I reiterate with emphasis: See also: ION, Covalence, Subatomic, Periodic, Peptide, Virulence, Cytosis, Virus Expansion, Genotype, Ecosystem, and Cellulose: A Plant Cell Biology Game for ages 8-14+
The science behind these games links God’s Creation of sunlight and humidity to protection from the virus-driven degradation of messenger RNA via light-activated carbon fixation in cyanobacteria and microRNA-mediated protein folding chemistry at the origin of life. Facts have been detailed in Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 and Peptide synthesis at the origin of life 11/13/20
See also: Reversing the miRNA -5p/-3p stoichiometry reveals physiological roles and targets of miR-140 miRNAs 3/24/22
miR-140 changes the first nucleotide in vivo. That fact links quantum coherence to coherently organized biology  at the origin of life to
See: Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20. It links protection to every aspect of God’s Creation of all life on Earth via microRNA-mediated protection from viruses that cause everything from COVID19 to cancers.
My summary: It links an energy-dependent (ATP-dependent) pH-dependent change in one nucleotide to God’s ATP-dependent Creation of RNA (and RNA interference) to claims made by McEwen et al. (1964)
See: Functions and underlying mechanisms of miR-650 in human cancers 3/24/22 Taken together, what’s known about microRNA-mediated disease prevention links the lab-based creation of SARS-CoV-2 to promotion of synthetic mRNA vaccines that block naturally occurring RNA interference () and DNA repair in specific tissues.
See for examples: Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line 2/25/22

Our results indicate a fast up-take of BNT162b2 into human liver cell line Huh7, leading to changes in LINE-1 expression and distribution. We also show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h upon BNT162b2 exposure.

Effects of BNT162b2 on the liver, spleen, adrenal glands, ovaries, and testes are opposed by the microRNA-mediated inactivation of the cell death gene, which was reported as Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene 9/2/11 after discovery of the “death gene” by researchers from Abcam in the late 1990’s.
On 3/25/22, a friend mentioned the intelligence community had evidence that suggested bioterrorists were trying to create a cell death gene to reduce fertility to zero. His mathematical models obfuscated the fact that reactivation of human endogenous retroviruses (HERVs) and reduced fertility via reverse transcription of the Pfizer BioNTech COVID-19 mRNA vaccine would probably suffice in the context of population control.
Fast forward to Symcel’s Science Blog. It links God’s Creation of sunlight and humidity to biophysically constrained viral latency via microcalorimetry and this report on SARS-CoV-2 Infection: Host Response, Immunity, and Therapeutic Targets 3/23/22

…we discuss experimental models to study SARS-CoV-2 infection, molecular pathways involved in SARS-CoV-2-induced inflammation, and viral hijacking of anti-inflammatory pathways

Start with energy-dependent creation of the cell wall in A single amino acid substitution in the MurF UDP-MurNAc-pentapeptide synthetase renders Streptococcus pneumoniae dependent on CO2 and temperature 6/28/13. Link the facts about fixation of amino acid substitutions to sex differences and ethnicity via construction and maintenance of the cell wall, which typically prevents viral hijacking of anti-inflammatory pathways.

…in capnophilic S. pneumoniae strains from CC156 and CC344 cell wall synthesis is placed under control of environmental CO2 levels and temperature. This mechanism might represent a novel strategy of the pneumococcus to rapidly adapt and colonize its host under changing environmental conditions.

Rapid adaptations are nutrient-dependent, and pheromone-regulated genetic processes of reproduction link biophysically constrained viral latency across kingdoms via species-specific tissue-specific construction of cell walls.
See also this recapitulation of the claims from: Cellulose for ages 14+

For the link from changing environmental conditions to microRNA-mediated survival in pediatric patients with cancer, see: Regulation of Nuclear Hormone Receptors by MYCN-Driven miRNAs Impacts Neural Differentiation and Survival in Neuroblastoma Patients 7/7/16

Our findings reveal a key role for the miR-17~92-regulated NHRs in neuroblastoma biology, thereby providing a potential differentiation approach for treating neuroblastoma patients.

See the attempt to obfuscate cause and effect via use of the term “non-homologous end joining” instead of alternative splicings of pre-mRNAs, which are now called microRNAs in more than 138,940 indexed publications that mention microRNAs.
For information on microRNA-mediated erectile dysfunction, see: MicroRNAs in aging male reproduction.  4/5/22

See also: NHEJ disruption and HDR correction? 6/14/18

With minimal investigation of what is known to serious scientists about biophysically constrained viral latency, you can find that acronyms such as NHEJ are used to obfuscate cause and effect in attempts to avoid litigation because the researchers should have known what might happen if the “death gene” was inactivated by the virus used in gene editing and in the lab-based creation of SARS-CoV-2 via changes in amino acid substitutions linked to furin cleavage. See for comparison anything linked to ecological adaptations and species diversity by human endogenous retroviruses (HERVs).
For example: When Genes Go Walkabout (2004)

Charles Darwin was wise enough not to pin down what he could not see or know, and so, he did not overly pontificate on how the changeability of nature was encoded, and how that code could be altered in its details.

See also: The Darwin Code: Intelligent Design without God 4/14/15
Gene-centric theorists, feminists, and conspiracy theorists and other atheists will continue to prevent you from learning the facts.
See: The map of our DNA is finally complete. Here’s what that means for humanity. 3/31/22

George Church, a geneticist at Harvard University who was not involved in the new work, described it as a major scientific achievement.

George Church et al., hold the patent for naturally occurring light-activated carbon fixation in cyanobacteria and microRNA-mediated protein folding chemistry, which protects all organized genomes from all virus-driven diseases. See: RNA-Guided Human Genome Engineering
See also our section on molecular epigenetics in: From fertilization to adult sexual behavior (1996)
When it becomes clear that George M. Church patented the facts about molecular epigenetics, move forward to:
Eliminating existential threats (1) (in prep)

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