RNA-mediated silencing (10)

By: James V. Kohl | Published on: April 11, 2022
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Stopping pandemics before they start: Lessons learned from SARS-CoV-2 3/11/22

The impact of COVID-19 on human health in 2020 alone was estimated to be estimated  to cost more than $2 trillion.

Light-activated pH-dependent carbon fixation in cyanobacteria and microRNA-mediated protein folding chemistry clearly link the potential of hydrogen (pH) to all biodiversity on Earth via MicroRNAs in Mechanical Homeostasis 4/4/22.
Food energy-dependent pheromone-regulated genetic processes of RNA interference (RNAi) and biophysically constrained viral endemicity across kingdoms were linked from the ATP-dependent Creation of RNA to oxidative phosphorylation and RNAi via ingestion of the naturally occurring precursor present in high concentrations in cruciferous vegetables and the antiviral activity of sulforaphane (SFN), the principal biologically active phytochemical derived from glucoraphanin.
Summary: Pandemics are stopped before they start, and they end via the epigenetic effects of food energy on pheromone-regulated fixation of amino acid substitutions in species from soil bacteria to humans. If 2 trillion dollars was spent to teach people about ecological variation in soil types, which link light-activated carbon fixation in cyanobacteria from plant growth to proper nutrition via microRNA-mediated protein folding chemistry, there probably would have been no SARS-CoV-2 pandemic.
See for example:  Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice 3/18/22

The pathogenesis of many viral infections is associated with increased production of reactive oxygen species (ROS), which leads to cell death. Conversely, SFN increases antioxidant, anti-inflammatory, and antiviral defenses through multiple mechanisms.

But, some people claim that “…the mechanistic effects of miR-638 on cancer cells are still controversial.” See for example: miR-638: A Promising Cancer Biomarker with Therapeutic Potential  4/5/22 (From researchers in Iran)
For a historical perspective on the controversy that links energy-dependent microRNA-mediated biophysically constrained viral latency across kingdoms, see Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

Several patents for naturally occurring light-activated carbon fixation and ATP-dependent microRNA-mediated protein folding chemistry have been linked to RNA interference and to the prevention or effective treatment of all virus-driven pathology across kingdoms.
But see: Medical experts rip Trump’s suggestion that sunlight, disinfectants may treat coronavirus 4/23/20
Former President Trump linked God’s Creation of sunlight and humidity to the refutation of all gene-centric theories. The stupid theories failed to link light-activated carbon fixation in cyanobacteria to microRNA-mediated protein folding chemistry and biophysical constraints on virus-driven pathology across kingdoms.
For updated pseudoscientific nonsense from USA Today, see: The map of our DNA is finally complete. Here’s what that means for humanity. 3/31/22
George M. Church, who patented naturally occurring light-activated epigenetic effects on RNA interference (RNAi) as the cure or effective treatment for all virus driven diseases, reportedly claimed

It’s a huge milestone that should be celebrated.

See for comparison from 11/15/12

In this representation of top-down energy-dependent causation, Eric Lander, who was Joe Biden’s science advisor, linked RNA interference (RNAi) to protection from the virus-driven degradation of mRNA across kingdoms. He resigned because he was reported to be a bully.
Is everyone who reports on God’s scientific truth a bully?

 The War in Ukraine Is Threatening the Breadbasket of Europe 4/5/22

“The “autoblock” feature… seems to fall under the category of restrictions on user communications that are not in fact prohibited by Twitter’s own rules, but that the site would still rather suppress.”

Welcome again to Socialism via public heath fascism. I discussed this with a friend who thought that the attacks were not political in the context of attacks on my scientific credibility made by Susie Byrne, Leslie Thurston, Tammy Allenduff, and Tracy Moore, who I collectively refer to as the “mean girls” because they do not act like intelligent adults. Instead, they call me a “bully” and contribute to suppression of the facts I have detailed. If that sounds familiar, it may be due to the fact that their tactic has been linked to suppression of the facts about COVID19 reported by former President Donald J. Trump on 4/23/20.

Three days ago, I discussed the facts in the context of the belief that the Ukraine war is being fought because of the supply chain of grain to Europe and the Middle East. So, I fact-checked the claims.

I linked the facts to the microRNA-mediated future of humanity, and so did former President Trump via his 4/23/20 claim that sunlight and humidity weaken virus-driven pathology.See also: Roles and clinical application of exosomal circRNAs in the diagnosis and treatment of malignant tumors 4/5/22

My summary: This review provides a theoretical basis for facts detailed by Dr. Thomas Ichim in the context of light-activated carbon fixation and microRNA-mediated protein folding chemistry for applications of exosomal circRNAs in malignant tumor diagnosis and treatment.
On 4/5/22 I tweeted: In the current issue of Science Magazine you will find evidence that gene-centric theorists claim is filling the gaps. It does no such thing.
See:  4/4/22 “Mechanical homeostasis is characterized by negative feedback…” Food energy fills the gaps.
Thomas E. Ichim replied Great find ! Thank you
I wrote: It will take a dedicated team to prevent experimentally established facts from being placed back into the context of gene-centric theories. For instance, page 7 of “Drug Discovery News” (April 2022) touts “A Mysterious Cellular Tango” as if no one knows it is light-activated.
This was Ichim’s reply.
Someone please follow my boy…having 666 is not good lol
I asked for clarification:  What does that mean? Can it be placed into the context of any of your patents for comparison to the one for the ATP-dependent prevention of all virus-driven pathology across kingdoms?

Second request for clarification. Do any of your #patents link naturally occurring light-activated #carbon_fixation in #cyanobacteria to biophysically constrained #microRNA-mediated protein folding #chemistry & #viral_endemicity across kingdoms via https://www.kickstarter.com/projects/geniusgames/cellulose-a-plant-cell-biology-game
See: Eliminating existential threats (in prep)

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[…] HomeMicroRNA-mediated existential threats (1) April 17, 2022 James Kohl Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News No Comments See: RNA-mediated silencing (10) […]


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