MicroRNA-mediated existential threats (2)

By: James V. Kohl | Published on: April 22, 2022

On 6/26/19, a friend and I stopped at the Scopes Museum in Dayton, Tennessee to make sure I could view this presentation on my laptop computer via a hotspot wi-fi connection.
See: Genome-Wide Study Reveals a Novel Regulatory Pathway: Translation Affects mRNA Stability in a Codon-Dependent Manner 6/26/19 (available for free on demand with registration).
I may try to find my pictures, or my on-location video to show that, as predicted, the presentation put an end to all the nonsense about natural selection for beneficial mutations and evolved biodiversity during billions to millions of years. That pseudoscientific nonsense has been touted since it began, a few decades after the time of the Scopes Trial in 1925.
On 6/26/19, Ariel Bazzini presciently established that God’s ATP-dependent Creation of RNA links microRNA-mediated pH-dependent fixation of amino acid substitutions from quantum coherence to coherently organized biology via microRNA-mediated stem cell creation.
See: MicroRNAs organize intrinsic variation into stem cell states 3/5/20

…naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology.

See also: Codon identity regulates mRNA stability and translation efficiency during the maternal-to-zygotic transition 7/9/16

The amino acid optimality code (Fig 6) provides an alternative perspective on sequence changes between paralogs in evolution and human disease.

See for comparison to Bazzini’s works: Exploring evolutionary immunogenomics: Lessons from our ancestors and past pandemics 4/20/22
It’s a theory-based killer of men, women, and children.

During this webinar, viewers will:

Gain insight into how past pandemics, such as Yersinia pestis, the agent of the Black Death, led to the evolution of the human immune system

Discover how the unique immunogenetic variation in present-day populations has impacted population differences in immune response to pathogens and susceptibility to immune-related disorders

Learn how cutting-edge techniques, such as RNA sequencing (RNA-seq), are used in evolutionary immunogenomics

SARCASM ALERT:  Someone else may want to link the pseudoscientific nonsense about evolutionary immunogenomics to unnecessary suffering and premature death. No wait! They already have. It seems like only yesterday, because that’s when it happened.
See: Codon optimality-mediated mRNA degradation: Linking translational elongation to mRNA stability 4/21/22

…transient pauses induce a unique ribosome conformational state that is probed by the deadenylase complex, thereby inducing an orchestrated set of events that enhance both poly(A) shortening and cap removal. Together, these data imply that the coding region of an mRNA not only encodes for protein content but also impacts protein levels through determining the transcript’s fate.

See also: autophagy.pro microRNA.pro and learn more about how to prevent virus-driven existential threats at RNA-mediated.com as this 10-part series continues.

 


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