The physics of existence (5)
(click to enlarge)
Freedom of thought allowed me to link food energy-dependent fixation of amino acid substitutions in microtubules to pheromone-regulated genetic processes of viral endemicity, healthy longevity, and symptatric speciation across kingdoms via the ATP-dependent Creation of RNA, first mentioned in McEwen et al., (1964)
See: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
For comparison, see:
Down-regulated miR-146a expression with increased neutrophil extracellular traps and apoptosis formation in autoimmune-mediated diffuse alveolar hemorrhage 8/26/22
Increasing evidences have suggested an important role of microRNAs (miRNAs) in regulating cell death processes…
See also: Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene 9/2/11
When I was told by someone who claimed to be on the team of researchers working for Abcam at the time they discovered the “death gene” in the late 1990’s, I learned the facts had already been suppressed for more than a decade.
For instance, in 2012, I learned that everything that happens to organized genomes happens downstream from energy-dependent microRNA-mediated cell type differentiation. That fact was clarified via publication of MicroRNAs organize intrinsic variation into stem cell states 3/5/20, which linked quantum coherence to coherently organized biology in the context of miRNAs as Biomarkers in Disease: Latest Findings Regarding Their Role in Diagnosis and Prognosis 1/23/20
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of regulating mRNA through its degradation and adjusting protein levels.
See also MicroRNA Involvement in Signaling Pathways During Viral Infection 3/10/20 and Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20
The facts also appear in the context of Viruses Can Scatter Their Genes Among Cells and Reassemble 5/21/19 and in Virus Mania: Corona/COVID-19, Measles, Swine Flu, Cervical Cancer, Avian Flu, SARS, BSE, Hepatitis C, AIDS, Polio, Spanish Flu. How the Medical Industry Continually Invents Epidemics, Making Billion-Dollar Profits At Our Expense (2021).
The ability to target miRNA involvement in signaling pathways has been linked to food energy since the time Richard P. Feynman discussed it in the context of stupid theories invented by other physicists.
VIDEO
See also: A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission 2/3/07
The change in hemagglutinin is biophysically constrained by food energy and pheromone-regulated genetic processes of reproduction.
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2
0
Survivors of RNA-mediated terrorism
5
0
Energy-dependent maternal-to-zygotic transition
6
1
Virus-driven mutation or amino acid substitution
5
0
Epigenetically effected energy-dependent fluorescence
5
0
Polycombic ecological adaptation as a science, not a theory (2)
12
0
Did evolution autophosphorylate your kinases? (3)
2
1
Did evolution autophosphorylate your kinases? (2)
5
1
Hypothesis free pseudoscience vs facts (4)
5
0
Hypothesis free pseudoscience vs facts (3)
3
0
The last RNA-mediated theory killer
< 1
0
Chromatin: The structure of DNA
6
0
Hydrogen-atom energy in DNA base pairs
6
0
Light energy-induced base pair changes (2)
4
0
Light energy-induced base pair changes (1)
6
0
Increased soil pH and nutrient availability
4
0
Virus-driven energy theft: honeybee model
3
0
Antithetical conclusions (7)
3
0
Anthetical conclusions (2)
5
0
The Origin of Information (2)
6
0
Did “Nature” kill Steve Jobs?
3
0
Energy-dependent RNA methylation (7)
7
0
Energy-dependent RNA methylation (4)
5
0
Virus-driven energy theft: definition?
5
0
Energy-dependent creation and entropy
4
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5
0
RNA-mediated physics, chemistry, and molecular epigenetics
9
0
MicroRNAs and/or QTLs: Who buried what?
2
0
Molecular Diagnostics: What is unprotected life (4)
2
0
Genome-gate: Follow the money?
4
0
Creating nutrient-dependent life with enough genes to survive
3
0
Confusing effects and affects of visual input
2
0
Ignore the evidence: Rachel Feltman
5
0
Energy-dependent purpose vs teleophobic telorexia
12
0
Stress-linked population-level history dependence
5
0
Do not miss the misrepresentations
2
0
Energy dependent RNA-mediated immunity (5)
4
0
Energy dependent RNA-mediated immunity (4)
6
0
Energy dependent RNA-mediated immunity (2)
10
0
Science vs semantics
4
0
Bacteria see the light and they adapt (2)
5
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3
0
Effects on invertebrate GnRH and affects on primate behavior
6
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA
2
0
Hydrogen-atom transfer in DNA base pairs (7)
5
0
Bacteria see the light and they adapt
7
0
Will modern human populations adapt to the Zika virus?
5
0
The unoffically uninvited
3
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3
0
Finding peace and π in the light of H bond energy
5
0
Epigenetic (re)programming of behavior
4
0
Life history transitions and RNA-mediated survial
2
0
Did Dobzhansky see the UV light of creation?
10
0
Manufacturing fossil “evidence”
4
0
RNA-mediated theory killers (4)
9
0
RNA-mediated theory killers (2)
8
0
MicroRNAs vs Red Queen hypothesis
4
0
A two-faced protein enables RNA-mediated DNA repair
2
0
Life and death predicted by DNA methylation
3
0
Behavioral Immune System model
4
0
Theorists can’t understand biology
6
0
Neuroplasticity
4
0
Receptor methylation controls behavior
2
0
Models are not theories (2)
2
0
Fossils vs cell types and the brain
3
0
Unraveling the secrets of RNA-mediated events
2
0
Designing, engineering, and protecting biodiversity
3
0
The virome, microbiome, replisome and supercoiled DNA
2
0
Skip the politics; embrace the facts
5
0
700 million years of evolution?
5
0
Biophysically constrained or unconstrained?
2
0
Mutated mitochondrial genes vs Supercoiled DNA
2
0
RNA-mediated retrotransposon-mediated biodiversity
3
0
Mystery machine vs model (2)
2
0
Preventing genomic entropy
4
0
Energy and evolution: another opinion?
2
0
Supercoiled DNA constrains virus-driven genomic entropy
2
0
Let there be anti-entropic light (2)
4
0
Foundamentals of theory
4
0
Non-mainstream scientist shares Nobel prize in Medicine
3
0
Is mainstream science in “Science” pseudoscience?
5
0
Mechanisms of stress: from genes to cancer
9
0
Viruses come alive: Tree of life pseudoscience
6
0
Theorists have not seen the light (2)
3
0
Hijacked light energy and vertebrate pathology
4
0
Theorists have not seen the light
4
0
Alternative pre-mRNA splicing and ecological adaptation
7
0
Pathology: Eating and breathing viruses
2
0
Exosomes and the RNA-mediated future of medicine
5
0
Somatic hypermutation vs RNA-mediated events
2
0
Phytochemical link from the sun to cell types
2
0
Genome sequencing, cadherins, and quantum consciousness
6
0
“New” quantum biology. Pirating the old
3
0
Cell types, SNVs, CNVs, and chromosomes
3
0
Thermotolerance and Longevity
57
0
Is life the balance between quantum and classical physics?
3
0
Anti-entropic containment of energy: symbiosis 1.0
5
0
Information and communication (2)
6
0
Information and communication
2
0
From “Blood Music” to Evolution 2.0
5
0
Olfaction & the octopus and human genomes
3
0
Thermodynamic constraints did not evolve
3
0
Mammalian-wide interspersed repeats (MIRs)
2
0
Ecological speciation vs revised evolutionary syntheses
6
0
Ecology replaces the extended evolutionary synthesis
4
0
The stability of organized genomes (4)
3
0
The stability of organized genomes (3)
3
0
Epimutation.com: a domain of confusion
8
0
Light -induced nucleic acid-mediated gene duplication?
< 1
0
Viruses, amino acids, and somatic cell types (2)
5
0
RNA-mediated terms of virus-induced en-deer-ment
2
0
Domestication via a single amino acid substitution
2
0
Becoming biologically informed (3)
3
0
Easy editing: Reinventing our RNA world
3
0
Is photic-zone ribosomal diversity linked to all biodiversity?
2
0
Picornaviruses moving between primates (or not)
2
0
Faithfully repaired DNA
5
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6
0
MicroRNA controlled growth and brain development
7
0
MicroRNA – controlled ecological adaptations
5
0
Becoming biologically informed
2
0
Celebrating independence from ridiculous theories
3
0
“New” epigenetic mechanism for lifelong learning?
3
0
The sum of our RNA-mediated parts
2
0
Protein folding and Google page rank
2
0
Iron, ferritin, thyroxine
2
0
Virus-driven death by evolutionary theory
3
0
“Evolution” of sex differences?
2
0
Nutrient stress-induced RNA-mediated pathology
< 1
0
Amino acid substitutions are not mutations
2
0
What I cannot create I eliminate from discussion
3
0
Healthy mutants
2
0
Uniquely epigenomic gene regulation
2
0
Alternative splicings: epigenetics meets pharmacogenomics
4
0
Epigenetic regulation of aging by glycine and GnRH
5
0
Physicians who practice evolutionary medicine?
3
0
Pattern recognition: biogeochemical structure and function
5
0
Viruses and the human-like microbiome
3
0
Informing the biologically uninformed
< 1
0
I forgot. How do mutations cause evolution?
4
0
One amino acid substitution, genes, and brain activity
3
0
Batch effect vs epigenetic effects
3
0
Gene expression, immortality, and cancer
6
0
Scientists lose. A sci-fi author gains credibility
2
0
Vitamin B3 and DNA repair
4
0
Ignoring systems complexity (it’s too complicated)
3
0
Virus-driven cancer treatment and prevention
2
0
The microbiome, pharmacogenetics, and privacy
< 1
0
A special issue on nutritional epigenetics
5
0
Retinoic acid + one receptor regulate the genome
3
0
Epigenetics: microRNAs effect an integrative pathway
4
0
Protein isoforms do not evolve
3
0
Tissue type variation and expression of genes
< 1
0
From gut bacteria to breast milk and back
5
0
Chance mutations — not natural selection
5
0
How to find a “holy grail” under your nose
3
0
Physics, chemistry, light, and life
2
0
pH, water, amino acids and protein folding
4
0
An epigenetic mark links algae, worms, and flies
2
0
Effect and affect of a single base-pair change
4
0
Thermodynamics and protein folding landscapes
2
0
Feedback loops link insects to human brains
2
0
Viruses and cell type differentiation
3
0
RNA-mediated cell types and precision medicine
5
0
DNA Methylation and organized genomes
7
0
Misunderstanding cancer
7
0
Nutrient-dependent RNA interference (2)
4
0
Mutisensory integration: watching the paradigm shift
12
0
Origin of life and cancer (1,2,3)
2
0
Silencing genes and serious scientists
3
0
The miRNA/mRNA balance: a suboptimal strategy?
2
0
Nutrient-dependent microRNAs control cell types
6
0
Too many targets for theories
3
0
Creating nothing but a theory (3)
4
3
Creating nothing but a theory (2)
4
0
The quantum / classical RNA-mediated ‘tipping point’
3
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4
0
Quantum correlations/pseudoscience
3
0
Anti-entropic solar energy
5
0
Is DNA-directed transcription RNA-mediated?
2
0
RNA directed DNA methylation and cell types
4
0
From 3-D to epigenetically-effected 4-D genome make-up
5
0
Insect homology and diversity attributed to mutations
2
0
Comparing divergent model organisms
2
1
(click to enlarge)