The physics of existence (8)
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“A microRNA switch regulates the rise in hypothalamic GnRH…” 5/2/16 The microRNA switch linked fixation of a specific amino acid substitution in microtubules to cognition and to vertebrate behavior via achiral glycine in position 6 of the GnRH decapeptide.
See: GnRH replacement rescues cognition in Down syndrome 9/2/22
Co-authors include Ulrich Boehm with senior author Vincent Prevot. They link the pheromone regulated genetic processes of reproduction in soil microbes and gut microbes across kingdoms from Gut bacterial nutrient preferences quantified in vivo 9/1/22 to jawed vertebrate diversity via:
- Human pheromones: integrating neuroendocrinology and ethology 10/22/01
- Human pheromones and sexual attraction 2/1/05 and
- Feedback Loops Link Odor and Pheromone Signaling with Reproduction (2005)
See also our section on molecular epigenetics in: From Fertilization to Adult Sexual Behavior (1996). See for review: Nutrient-dependent/pheromone-controlled adaptive evolution: a model 6/14/13
Here is the model:
On 9/1/22, others began reporting this model of transgenerational epigenetic inheritance as:
Boosting cognition with a hormone
Restoring a key hormone could help people with Down syndrome
A therapy found to improve cognitive function in patients with Down syndrome
A Hormone May Boost Cognition in Down Syndrome
GnRH therapy could improve cognitive deficits in men with Down syndrome
Each report recapitulates the claims from my model of biophysically constrained viral endemicity, which was an evolutionary theory killer. Neo-Darwinian theorists hated the model because it showed they were too stupid to link God’s Creation of sunlight and humidity to biophysically constrained viral endemicity and healthy longevity via everything known to intelligent serious scientists about human endogenous retroviruses (HERVs).
See: The Darwin Code by Greg Bear
The acronym HERV–human endogenous retrovirus–became my mantra. In 1997 and 1998, I searched the literature (and the internet) for more articles about these ancient curiosities–and located a few pieces here and there, occasional mention in monographs, longer discussions in a few very specialized texts. I was especially appreciative of the treatment afforded to HERV in the Cold Spring Harbor text Retroviruses, edited by Drs. Coffin, Varmus, and Hughes. But to my surprise, the sources were few, and there was no information about HERV targeted to the general layman.
As a fiction writer, however, I was in heaven–ancient viruses in our genes! And hardly anyone had heard of them.
See also: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18
Watch as others try to catch up to the fact that Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections (4/23/20)
Down syndrome is a virus-driven disease. Effective treatment with GnRH links effective treatment of all virus-driven diseases to fixation of amino acid substitutions in microtubules across kingdoms.
See: Cellulose: A Plant Cell Biology Game for ages 14+ and
Hormone Treatment Improves Cognition in Down Syndrome 9/2/22
GnRH replacement rescues cognition in Down syndrome 9/3/22
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Human Pheromones: Epigenetic Effects on Hormones and Their Affects on Behavior
3 MIN READ
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Are human pheromones chemosignals?
2 MIN READ
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Human Pheromones: Epigenetic Effects of Odors and Their Affects on Behavior
2 MIN READ
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The same neural mechanisms are at work in worms and humans
2 MIN READ
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Pheromonemotionally speaking
2 MIN READ
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Nobel laureate challenges psychologists to clean up their act
2 MIN READ
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Human pheromones and the fusiform fooled you area for face recognition
3 MIN READ
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Playing with breasts (e.g, with a new THEORY of why only heterosexual men love them)
3 MIN READ
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Genetic test predicts autism risk
< 1 MIN READ
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Chemical conditioning of food reward and drug addiction
< 1 MIN READ
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Insect to human cognition
2 MIN READ
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What to do with research results: Warning!
2 MIN READ
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Human pheromones and the epigenetic effects of isolation
2 MIN READ
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Natural selection and the behavior of whole organisms
< 1 MIN READ
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Woefully ignorant politicians and popular science (2)
< 1 MIN READ
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Epigenetic effects on the evolution of behavior
2 MIN READ
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Copulins: Human pheromones effect physiology and affect social behavior
2 MIN READ
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Children’s healthy diets lead to healthier IQ
< 1 MIN READ
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Pheromones and the phylogeny of operant and classical conditioning
2 MIN READ
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Human Pheromones: Diversity of signaling pathways and a common response (Part 2)
2 MIN READ
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Human Pheromones: Diversity of signaling pathways and a common response
< 1 MIN READ
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Human pheromones are like sugar (and spice)
< 1 MIN READ
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Is Science Metaphysically Neutral About Free Will?
2 MIN READ
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Oxytocin for everything?
2 MIN READ
1
A neuroscientific perspective on neurobiological differences in everyone
2 MIN READ
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Human pheromones and altruism
3 MIN READ
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Human Pheromones and Multi-level selection
< 1 MIN READ
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Where is the love?
3 MIN READ
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Human pheromones: Olfaction, odor receptors, learning, memory, mood, brains and behavior
< 1 MIN READ
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Human pheromone- and nutrient-dependent brain development and behavior
2 MIN READ
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Human pheromones and the visual appeal of other people (Part Three)
2 MIN READ
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Human pheromones and the visual appeal of other people (Part one)
2 MIN READ
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Human pheromones and brain development
2 MIN READ
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Pre-existing genetic variability or random mutations: a matter of priorities and choices
2 MIN READ
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Human Pheromones and Common Scents: Plants and Perfume
< 1 MIN READ
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People select specific fragrances that suit their individual body odor
< 1 MIN READ
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A fear of pheromones (revisited)
3 MIN READ
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A fallacious leap? Ancestral and derived traits
3 MIN READ
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Human Pheromones in Socioaffective Neuroscience & Psychology
2 MIN READ
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They are what they eat, and so are we
2 MIN READ
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History of intelligence (550 words)
2 MIN READ
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A Preoccupation With Modesty…
2 MIN READ
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The biology of behavior: Seeing more clearly
< 1 MIN READ
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Do Pheromones Play a Role in Our Sex Lives: Scientific American
< 1 MIN READ
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Epigenetics and the connectome
2 MIN READ
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Docosahexaenoic acid and autism: praying for hope, or preying on hope
< 1 MIN READ
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Timing is key in the proper wiring of the brain: study
2 MIN READ
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Behavioral epigenetics
2 MIN READ
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Baiting evolutionary psychologists and others who damn religion
3 MIN READ
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Human Pheromones may influence brain chemistry into adulthood
< 1 MIN READ
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Show me the science!
5 MIN READ
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Baiting the behaviorist(s)
3 MIN READ
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Theory versus biological facts: Mental modules and models for behavior
2 MIN READ
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An organizing principle for our sense of smell
< 1 MIN READ
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Men and women who stare at goats…
2 MIN READ
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The “yuck” factor: aversion to social odors?
2 MIN READ
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The Mind’s Eyes: Mindful modeling of brain directed behavior
2 MIN READ
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Study results: Human pheromones affect women’s behavior
< 1 MIN READ
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Human Pheromones and the Biology of Behavior
5 MIN READ
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Human Pheromones Affect Women's Behavior
2 MIN READ
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A lesser role for olfaction and pheromones in humans?
1 MIN READ
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Study results: Human pheromones influence human behavior
2 MIN READ
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The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
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The great pheromone myth revisited (including biological factors in the development of sexuality)
4 MIN READ
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Wikipedia comments by James V. Kohl
5 MIN READ
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Genes, Hormones, and Behavior (for other scientists)
4 MIN READ
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A fundamental attribution error: Love at first sight
3 MIN READ
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Human pheromones in tears automagically effect testosterone
2 MIN READ
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Tears and fears of pheromones
2 MIN READ
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Exotic Pheromones and Concentrates
2 MIN READ
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Human Pheromones, The Scent of Eros, and Cultural Evolution
< 1 MIN READ
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Study Results: Human pheromones increase flirtatious behavior and ratings of attraction
2 MIN READ
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Is it what he or she sees in you, or is it your pheromones?
2 MIN READ
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Conditioning of the human pair bond by human pheromones
< 1 MIN READ
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Human pheromones work by effecting hormones that affect behavior
2 MIN READ
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Conditioned sexual arousal to odor
2 MIN READ
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American and Canadian Mensa Presentation
< 1 MIN READ
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The Great Pheromone Myth (opinion/review)
19 MIN READ
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Human Pheromones and Face Preferences
< 1 MIN READ
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Human Pheromones, DHEA and WHR
2 MIN READ
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Human Pheromones and Brain activation
2 MIN READ
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Human pheromones do not create desire . . . they enhance it!
< 1 MIN READ
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Scent of a woman: Men’s Testosterone Responses to Women's Scent
< 1 MIN READ
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Luteinizing hormone, sex, and smell (18 years later)
2 MIN READ
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