Pheromone-regulated genetic processes (1)
(click to enlarge)
See: The physics of existence (1 -10)
Moving forward:
Microtubule regulation: Transcending the tenet of K40 acetylation 2/7/2
…acetylation of lysine 394 in α-tubulin also mediates microtubule stabilisation in neurons.
That fact has been linked to The potential role of the mobile and non-coding genomes in adaptive response 9/1/22
Energy-dependent pheromone-regulated genetic processes of reproduction link miRNAs and human endogenous retroviruses (HERVs) from feedback loops to viral endemicity or to healthy longevity across kingdoms via fixation of amino acid substitutions in microtubules via the role that glycine plays in construction of the cell wall, which constrains viral endemicity across kingdoms.
If you have 2.5 hours to waste, see this moronic display of human idiocy by the “snake was Right” for comparison.
VIDEO
For facts, see: MiR-34a-5p promotes hepatic gluconeogenesis by suppressing SIRT1 expression natural selection for energy-dependent codon optimality .
For example, changes in host fitness protect against the virus-driven degradation of messenger RNA, which links mutations to all virus-driven pathology. Fixation of amino acid substitutions in microtubules and constraints on human endogenous retroviruses (HERVs) are the key to longevity in this model:
For comparison, nutritional stress and social stress cause constraint breaking mutations. See: Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections 4/23/20 and
VIDEO
See also: Pheromonal Regulation of Genetic Processes: Research on the House Mouse (1994)
The failure to link the metabolism of food to pheromone-regulated feedback loops and regulation of social stress is the epic failure of all stupid theorists. They may kill us all rather than admit they have always been wrong.
Sabine Hossenfelder is a noteworthy exception:
VIDEO
The Big Bang is the simplest explanation to the universe that we know, and it’s probably wrong.
Neo-Darwinian theorists built their theories on claims about cosmology that have never been validated with experimental evidence of top-down energy-dependent causation, which must be linked to the physics of existence via what is known to chemists and molecular biologists.
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The tipping point? 50, 000 publications (2)
2
0
Countdown to Genetics and Genomics
< 1
0
Energy-dependent creation and entropy
4
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5
0
RNA splicing, genetic variation, and disease
2
0
From nothing to life and death everywhere
5
0
Molecular Diagnostics: What is unprotected life? (5)
5
0
Confusing effects and affects of visual input
2
0
Selective reporting of inferences: examples of pseudoscience
14
0
Energy-dependent purpose vs teleophobic telorexia
12
0
Stress-linked population-level history dependence
5
0
Energy-dependent RNA-mediated immunity (1)
10
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands (2)
3
0
Effects on invertebrate GnRH and affects on primate behavior
6
0
Hydrogen-atom transfer in DNA base pairs (7)
5
0
Bacteria see the light and they adapt
7
0
The Light and Darkness of “Evolution 2.0”
11
0
Cancer: Evolution 2.0’s Blind Spot
13
0
Blood test links atoms to ecosystems
2
0
Another failed rescue attempt
5
0
Juvenile hormone links atoms to ecosystems
3
0
Genes, orchid odors, and pheromones from blonds
5
0
Amino acid substitutions, stress, and human behavior
3
0
Finding peace and π in the light of H bond energy
5
0
Assumptions prove ignorance
5
0
RNA-mediated theory killers (4)
9
0
RNA-mediated regulatory mechanisms link microbes to humans (3)
5
0
RNA-mediated theory killers (2)
8
0
Natural cooperation and Evolution 2.0
6
0
Sulfated steroids and RNA-mediated identity codes
< 1
0
A two-faced protein enables RNA-mediated DNA repair
2
0
Nutrient-dependent trophic analogs
3
0
Stress-perturbed mitochondrial dysfunction (2)
5
0
Theorists can’t understand biology
6
0
Sensationalizing no new mechanism
2
0
Conserved molecular mechanisms
< 1
0
RNA central and RNA-mediated.com
6
0
Skip the politics; embrace the facts
5
0
Mystery machine vs model
2
0
Preventing genomic entropy
4
0
Supercoiled DNA constrains virus-driven genomic entropy
2
0
Let there be anti-entropic light (2)
4
0
Mechanisms of stress: from genes to cancer
9
0
Theorists have not seen the light
4
0
A 5-10K comparison of design principles to evolution
3
0
Alternative pre-mRNA splicing and ecological adaptation
7
0
Multi-omic analysis features (SNPs, miRNA)
3
0
Genome sequencing, cadherins, and quantum consciousness
6
0
“New” quantum biology. Pirating the old
3
0
Cell types, SNVs, CNVs, and chromosomes
3
0
Anti-entropic containment of energy: symbiosis 1.0
5
0
The “great filter” is an epigenetic trap
4
0
Information and communication (2)
6
0
Olfaction & the octopus and human genomes (2)
4
0
The stability of organized genomes (3)
3
0
Viruses, amino acids, and somatic cell types (3)
9
0
Viruses, amino acids, and somatic cell types (2)
5
0
Viruses, amino acids, and somatic cell types
4
0
Becoming biologically informed (3)
3
0
Easy editing: Reinventing our RNA world
3
0
Riding the wrong direction
3
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6
0
MicroRNA controlled growth and brain development
7
0
MicroRNA – controlled ecological adaptations
5
0
Is SUMOylation RNA-directed DNA methylation? (revisited)
4
0
“New” epigenetic mechanism for lifelong learning?
3
0
Iron, ferritin, thyroxine
2
0
RNA-mediated development
2
0
Ignoring top-down causation
2
0
microRNAs, glycosylation, and genomes
4
0
Alternative splicings: epigenetics meets pharmacogenomics
4
0
Epigenetic regulation of aging by glycine and GnRH
5
0
Pattern recognition: biogeochemical structure and function
5
0
Informing the biologically uninformed
< 1
0
Batch effect vs epigenetic effects
3
0
Vitamin B3 and DNA repair
4
0
Ignoring systems complexity (it’s too complicated)
3
0
Five years of Ferguson
2
0
Virus-driven cancer treatment and prevention
2
0
A special issue on nutritional epigenetics
5
0
Retinoic acid + one receptor regulate the genome
3
0
Epigenetics: microRNAs effect an integrative pathway
4
0
Protein isoforms do not evolve
3
0
From gut bacteria to breast milk and back
5
0
Viruses in gut microbes
4
0
MicroRNAs and the exposome
5
0
Thermodynamics and protein folding landscapes
2
0
RNA-mediated silencing of a chromosome
3
0
Pathology constrains X-linked evolution
2
0
Feedback loops link insects to human brains
2
0
Misunderstanding cancer
7
0
Amino acid-dependent cell type differentiation
8
0
Mutisensory integration: watching the paradigm shift
12
0
Origin of life and cancer (1,2,3)
2
0
Nutrient-dependent microRNAs control cell types
6
0
Too many targets for theories
3
0
Methylation maintains cell type differences
3
0
Creating nothing but a theory
4
0
2 genes in 2 species (too expensive and too insignificant)
11
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4
0
Quantum correlations/pseudoscience
3
0
Mimicking claims and ignoring facts
4
0
Questions about life’s diversity
21
0
Luis P. Villarreal tells it like it is
3
0
RNA-directed gene choice
5
0
Assembling yourself: Molecular self / other recognition
4
0
What about birds?
5
0
Implicating microRNAs in cancer
2
0
Let there be anti-entropic light (1)
11
0
An epigenetic trap (the prequel)
5
0
Nutritional epigenetics, exercise, and immune system integrity
4
0
What if Darwin was not still dead?
2
0
Military combat training to fight disease (2)
3
0
How fast can evolutionary theory be changed?
5
0
Quantum Superpositions: let there be light
4
0
Quantum entanglement, mass, and biomass
4
0
Constrained evolution is ecological adaptation
5
0
From Hydra to humans vs a Lakatosian research program
4
0
Unified nutritional and molecular mechanisms
9
0
Models by evolutionary biologists are not models
2
0
Chemical ecology and RNA-mediated control of DNA loops
< 1
0
Jumping back: Science or Pseudoscience? (2)
2
0
Glycine and GnRH: Am I being pedantic?
4
0
Extensive molecular evidence vs ridiculous theories
2
0
Meaningful dialogue, anonymous fools and idiot minions
4
0
Sackler Colloquium: Effects or AFFECTS on Behavior
2
0
Achiral GnRH: no prophesy, just prediction
9
0
RNA eclipses the importance of DNA to cell type differentiation
4
0
Evolutionary theorists justify fear of the Ebola viruses
2
0
RNA-mediated genetic engineering (Part 3)
< 1
0
Forces of "Nature" limit dissemination of information
4
0
Systems biology and memory disorders
3
0
Physics, Chemistry, and Molecular biology (PCMb)
2
0
RNA-directed DNA methylation and RNA-mediated events
5
1
Seemingly futile cycles are not thermodynamically futile
3
0
microRNAs differentiate neuronal cell types
3
0
The quantum biology of consciousness
3
0
Cell-type differentiation
2
0
Pheromone-controlled thermodynamics and cancer
2
0
Seeds of life: astrobiological theory and mutations theory
3
0
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