Pheromone-regulated genetic processes (3)

By: James V. Kohl | Published on: September 14, 2022

See: Pheromone-regulated genetic processes (2)

miRNAs: Regulators of Immune System in Diabetes 9/9/22 and MicroRNA-96 in human cancers 9/9/22 link food energy-dependent pheromone-regulated genetic processes of reproduction in flies and mosquitoes to this update on the works of TH Morgan (1910).

Analysis of Aedes aegypti microRNAs in response to Wolbachia wAlbB infection and their potential role in mosquito longevity 9/9/22

In Drosophila, expression of the 317/277/34 cluster is known to be controlled by the steroid hormone ecdysone82. miR-34-5p has been shown to affect lifespan in flies by modulating branched-chain amino acid catabolism83, and the ecdysone signalling pathway via downregulation of the E74A isoform of the transcription factor Eip74EF82,83,84.

For a historical perspective, see: Museum für Naturkunde Explores Maria Sibylla Merian’s Legacy and Editions of Her Metamorphosis

In 1679, Maria Sibylla Merian presciently linked peptide synthesis at the origin of life from light-activated carbon fixation in cyanobacteria to the pheromone-regulated genetic process of reproduction via fixation of amino acid substitutions in organized genomes across kingdoms.

See: Prothoracicotropic hormone of the silkworm, Bombyx mori: amino acid sequence and dimeric structure 1/1/91 and Ecdysone Control of Developmental Transitions: Lessons from Drosophila Research 10/15/12

…transition events are under strict endocrine control and have been of interest to entomologists for close to a century, since the classical study of Stefan Kopec () on the metamorphosis of the gypsy moth, Lymantria dispar. This pioneering work led to novel concepts such as neurosecretory cells (, ), contributing greatly to the development of modern endocrinology.

Several key hormones and neuropeptides are involved in the control of insect developmental transitions…

Food energy-dependent pheromone-regulated genetic processes of hormone-dependent reproduction have since been linked to miRNA-mediated constraints on cell type differentiation via messenger RNA (mRNA) therapy.

See:  Nanoparticle-Based Follistatin Messenger RNA Therapy for Reprogramming Metastatic Ovarian Cancer and Ameliorating Cancer-Associated Cachexia 9/13/22

By altering the cancer cell phenotype, mRNA treatment prevents malignant ascites, delays cancer progression, induces the formation of solid tumors, and preserves muscle mass in cancer-bearing mice by inhibiting negative regulators of muscle mass.

Reported as: Researchers develop messenger RNA therapy for ovarian cancer, muscle wasting

The treatment is based on the same principles used in SARS-CoV-2 vaccines, and the scientists say mRNA technology, though still in its infancy in terms of therapeutic application, holds tremendous clinical potential for the management of disease. Messenger RNA carries instructions to cells regarding the manufacture of proteins.

The comparison to injections with synthetic mRNA in vaccines can be placed into the context of this MEDICAL SHOCKER: Scientists at Sloan Kettering discover mRNA inactivates tumor-suppressing proteins, meaning it can promote cancer:

For comparison, George M. Church et al., illegally patented naturally occurring RNA interference as RNA-Guided Human Genome Engineering half a century after McEwen et al., (1964) reported on God’s ATP-dependent Creation of RNA.

Compare this claim from Church et al….

5. Repetitive elements or endogenous viral elements can be targeted with engineered Cas+gRNA systems in microbes, plants, animals, or human cells to reduce deleterious transposition or to aid in sequencing or other analytic genomic/transcriptomic/proteomic/diagnostic tools (in which nearly identical copies can be problematic).

….to this claim from McEwen et al., (1964) Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” 

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

Start with God’s Creation of sunlight and humidity. Link it to protection from all virus-driven pathology across kingdoms via the physiology of reproduction and Biblical Genesis. Remember to update your knowledge base to include facts that link fixation of amino acid substitutions in microtubules from miRNA-mediated protein folding chemistry to the end of unnecessary suffering and premature deaths via claims about viral endemicity in:

See also:

For comparison, see: Carlo Rovelli’s: Helgoland: Making Sense of the Quantum Revolution 3/25/21

We and everything around us exist only in our interactions with one another.

But wait, he cites the Mūlamadhyamakakārikā,

“[A]ll experienced phenomena are empty (sunya). This did not mean that they are not experienced and, therefore, non-existent; only that they are devoid of a permanent and eternal substance (svabhava) because, like a dream, they are mere projections of human consciousness. Since these imaginary fictions are experienced, they are not mere names (prajnapti).”[31]

Thank God, the clarification of pseudoscientific nonsense was placed into the context of Olfaction Warps Visual Time Perception 5/1/18 and Pheromone effects on the human hypothalamus in relation to sexual orientation and gender 7/17/21

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