miRNA-mediated epigenetic states (3)
(click to enlarge)
Long COVID: major findings, mechanisms and recommendations 1/13/23
“Reactivated viruses…lead to mitochondrial fragmentation and severely affect energy metabolism.”
https://www.nature.com/articles/s41579-022-00846-2
Sunlight and humidity typically constrain intrinsic chirality via the ATP-dependent Creation RNA and oxygen-dependent fixation of amino acid substitutions in microtubules that link miRNA-mediated protein folding chemistry to biophysically constrained human endogenous retroviruses (HERVs) via differences in human hemoglobin variants that prevent reactivation.
See for review: MicroRNA Detection and Target Identification
“Each protocol is provided in readily-reproducible step-by step fashion, opening with an introductory overview, a list of the materials and reagents needed to complete the experiment, and followed by a detailed procedure that is supported with a helpful notes section offering tips and tricks of the trade as well as troubleshooting advice. These hallmark features were introduced by series editor Dr. John E. Walker…”
https://link.springer.com/book/10.1007/978-1-0716-2982-6
McEwen et al., (1964) presciently linked intrnisic chirality from the adenosine triphosphate (ATP)-dependent Creation of the ribonucleic acids, RNA and DNA to biophysically constrained viral latency across kingdoms via what is now known about RNA interference (RNAi). Sir John Ernest Walker, a British chemist, studied ATP synthase in the 1970s. He linked the key enzyme in cellular energy conversion to the production of ATP from the mitochondria, which is the power-houses in our cells. Walker won the Nobel Prize in Chemistry in 1997. (Theorists claim that a cell that engulfed a bacterium led to the evolution of all other cells that contain mitochondria during billions to millions of years of human evolution from pond scum, or blue-green algae, which are not algae. They are photosynthetic cyanobacteria.
My model linked their physiology of pheromone-regulated reproduction to protection from viruses before I spoke to Bruce S. McEwen for the first time. In 1991, Bruce S. McEwen told me that my model of biologically-based top-down causation could not be validated without first showing that pheromones activated genes in gonadotropin releasing hormone (GrRH)-secreting cells that link food odors and pheromones to protection from the virus-driven degradation of messenger RNA. Everything known about the GnRH decapeptide has been linked from the origin of life to protection from the viruses that link mutations to all virus-driven diseases across kingdoms from microbes to humans.
After the discovery of microRNAs in 1993, all intelligent serious scientists began to realize their need to abandon stupid gene-centric theories. A few of them started to link quantum coherence to coherently organized biology via miRNA-mediated stem cell Creation and biophysically constrained cell type differentiation.
For comparison to facts that link photosynthesis to the energy captured in food and the pheromone-regulated genetic processes of reproduction, neo-Darwinian theorists doubled-down on their efforts. Most of them still link the emergence of energy in the cosmic void to stupid theories they claimed could explain how food energy is linked to building cellular components such as DNA and proteins to muscle contraction, transmission of nerve messages, and in many other signaling processes that intelligent scientists linked from the physiology of reproduction to every aspect of life on Earth.
For recent examples of human idiocy, see: “Mutations help genes emerge from aimless DNA 1/13/23 and Nick Lane’s “glory of evolution.”
For comparison, see: See also: The potential use of mesenchymal stem cells-derived exosomes as microRNAs delivery systems in different diseases 1/23/23 and A Trio of Genes Can Restore Epigenetic Integrity & Reverse Aging 1/18/23. Alternatively, suffer unnecessarily and die prematurely from a preventable or effectively treatable virus-driven disease.
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