miRNA-mediated epigenetic effects (7)

By: James V. Kohl | Published on: February 12, 2023

Modern biodiversity is energy-dependent and the metabolism of food to pheromones biophysically constrains stem cell Creation and cell type differentiation across kingdoms. The constraints link Merian’s claims from 1679 to The RNase III enzyme Dicer1 is essential for larval development in Bombyx mori 2/10/23 via Parallelized multidimensional analytic framework applied to mammary epithelial cells uncovers regulatory principles in EMT 2/8/23

Ecological adaptation occurs via the epigenetic effects of nutrients on alternative splicings of pre-mRNA which result in amino acid substitutions that differentiate all cell types of all individuals of all species. The control of the differences in cell types occurs via the metabolism of the nutrients to chemical signals that control the physiology of reproduction.

See: “….a workflow that simultaneously examines twelve omics modalities, i.e., protein abundance from whole-cells, nucleus, exosomes, secretome and membrane; N-glycosylation, phosphorylation; metabolites; mRNA, miRNA; and, in parallel, single-cell transcriptomes.” 2/8/23

See for comparison: One crank dies, another rises to take his place 1/6/14

These facts do not refute evolution; they simply refute the ridiculous theory of mutation-initiated natural selection that most people here were taught to believe is the theory of evolution.

Compare PZ Myers’ nonsense to claims that link the weekend resurrection of the bacterial flagellum in P. fluorescens to 2016 Chemistry Nobel Laureate, Ben Feringa’s claims in The Future of Chemistry – Schrödinger at 75: The Future of Biology via fixation of two amino acid substitutions across species. A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission 2/3/07

See: “extracellular vesicles” = “exosomal miRNAs”


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