Flipping off the flipons (5)

By: James V. Kohl | Published on: July 10, 2023

miRNA dosage control in development and human disease7/5/23

Naturally occurring light-activated carbon fixation in cyanobacteria was patented as “RNA-guided human genome engineering” by profiteers who refuse to link pheromone-controlled genetic processes of reproduction to constraints on stem cell Creation and cell type differentiaion via RNA interference, the 2002 “Science Breakthrough of the Year.

See for review The discovery and potential of RNA interference 11/15/12

The profiteers, like those at Pfizer, refuse to link light-activated miRNA dosage control to development via prevention of virus-driven human diseases such as SARSCoV2, Cancer, and Alzheimer’s, which can now be treated with microtubule inhibitors.

Thankfully, effective, treatment with microtubule inhibitors was linked to Kinome Profiling 9/2/12 via reports from 1964 on the ATP-dependent Creation of RNA in regulatory T cells, and fixation of amino acid substitutions that differentiated the cell types of primates.

“”Ingram and others found that hemoglobin S differs from A in the substitution of just a single amino acid, valine in place of glutamic acid in the beta chain of the hemoglobin molecule.”

See for comparison: This map of Hutterite colonies shows evolution at work 11/23/21

“Speciation is the biological process by which a single population evolves into different species. The typical cause is geographic isolation of a subgroup, which then becomes subject to another set of environmental pressures. In combination with genetic drift, this may result in a population with distinct habits and characteristics, which is no longer able to interbreed with the original species — in other words, a new species.”

Moronic claims about Hutterite colonies and speciation can be compared to facts about ecological adaptations and healthy longevity across kingdoms.

For an update, see A multi-omics integrative approach unravels novel genes and pathways associated with senescence escape after targeted therapy in NRAS mutant melanoma 7/7/23. It linked nearly 160,000 indexed published works that mention miRNAs to prevention or effective treatment of all virus-driven pathology across kingdoms in the context of Phenotypic Frailty Assessment in SAMP8 mice: sex differences and potential role of miRNAs as peripheral biomarkers 7/9/23 and The Hidden Players: Shedding Light on the Significance of Post-Translational Modifications and miRNAs in Alzheimer’s Disease Development 7/7/23

“The miRNAs are single-stranded RNAs that control gene expression by causing mRNA degradation, deadenylation, or translational repression and have been implicated in the regulation of several neuronal and glial activities.”

Food energy-dependent pheromone-regulated genetic processes of reproduction in yeasts and Hutterites link changes in the miRNA-mRNA balance to every aspect of gene expression that links the Creation of stem cells to cell type differentiation across kingdoms via the physiology of reproduction.

However, that fact must compete for press coverage with moronic theories like this: The Universe is flat. Here’s what that teaches us. 5/31/22

“In theory, the fabric of space could have been curved in any way imaginable. So why is the Universe flat when we measure it?”

See for comparison: Structural Mechanisms for Replicating DNA in Eukaryotes 3/30/21 reported on 7/7/23 as Cells have some clever tricks for copying DNA

“Today, researchers are making steps toward a full understanding of the molecular checks and balances that have evolved in order to ensure that each origin initiates DNA copying once and only once, to produce precisely one complete new genome.”

Claims that molecular checks and balances evolved have not been supported by any experimental evidence of links from quantum coherence to coherently organized biology. Ask a theorist why they believe in the pseudoscientific nonsense from the past, when the Hutterites exemplify biophysically constrained ecological adaptations in today’s world.


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