Total recall 6000 years (4)

By: James V. Kohl | Published on: October 14, 2023

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K-Homology Type Splicing Regulatory Protein: Mechanism of Action in Cancer and Immune Disorders

“…we provide an minireview of this important regulatory protein and describe its complex subcellular functions to affect RNA metabolism, stability, miRNA biogenesis and maturation, stress granule function, metastasis, and inflammatory processes.”

The energy-dependent miRNA-mediated mechanisms of action link alternative splicings of pre-mRNA across kingdoms and prevention of immune disorders to cancer prevention. Epigenetic effects of food odors and pheromones on alternative splicings and healthy longevity were reported in Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20.

The energy-dependent link from protonated RNA states to miRNA maturation, the ATP-dependent Creation of enzymes and healthy longevity across kingdoms appeared on 10/13/23 in the context of this report on Thousands of programmable DNA-cutters found in algae, snails, and other organisms

“Fanzors are RNA-guided enzymes that can be programmed to cut DNA at specific sites, much like the bacterial enzymes that power the widely used gene-editing system known as CRISPR.”

The so-called ‘Fanzors’ link naturally occurring light-activated endogenous substrates in pond scum/cyanobacteria/blue green algae to innate immunity and protection from the virus-driven degradation of messenger RNA in all cell types. It is likely that every intelligent serious scientist who ever refused to claim that Amino acid composition of proteins varies substantially between taxa and, thus, can evolve 1/19/05 already knows the facts. But Eugene Koonin is also a co-author of Programmable RNA-guided DNA endonucleases are widespread in eukaryotes and their viruses 9/27/23

The fact that light-activated RNA-guided DNA endonucleases protect all organized genomes from the virus-driven degradation of messenger RNA and all virus-driven pathology was placed into context, on 10/4/23 in “Nature.” See: How purposeless physics underlies purposeful life.

George FR Ellis, mentioned the need to use a model organism, such as C.elegans to validate the claims of theoretical physicists. Model organisms counter the claims of all moronic theorists who failed to link facts about God’s energy-dependent Creation of miRNAs and fixation of amino acid substitutions in microtubules to biophysically constrained viral latency across kingdoms via the pheromone-regulated genetic processes of reproduction in species from microbes to humans.

Please read about “microtubule inhibitors“

For comparison, see: “Breaking Through: My Life in Science” 10/10/23

Bill Gates claims “Katalin Karikó’s story is an inspiration.”

It promises to be an example of human idiocy that can be compared to claims that photosynthesis protects organized genomes from virus-driven pathology across kingdoms via KB Whaley’s group’s publication history and A quantum trajectory picture of single photon absorption and energy transport in photosystem II 10/7/23

KB Whaley was Trump’s scientific advisor. She told him how to link sunlight and humidity from changes in electron spin to inorganic and organic chemistry before he made his 4/23/20 claim that sunlight and humidity weaken coronaviruses.

WHO thinks I will be disappointed by starting with the understanding that God’s ATP-dependent Creation of RNA at the origin of life is the source for all oxygen-dependent biodiversity.

See for comparison: Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA 8/23/05

I think that anyone who claims that RNA evolved is a moronic theorist or killer profiteer.

See for comparison: TranslatorX: multiple alignment of nucleotide sequences guided by amino acid translations 4/30/10; De novo birth of functional microproteins in the human lineage 12/20/22 and “RNA-Guided Human Genome Engineering”

“5. Repetitive elements or endogenous viral elements [HERVs] can be targeted with engineered Cas+gRNA systems in microbes, plants, animals, or human cells to reduce deleterious transposition…”

Deleterious transposition is caused by the virus-driven theft of the sun’s anti-entropic energy in my model of what is known to all intelligent serious scientists and to Pfizer about constraints on viral latency in species from yeasts to humans.

Pfizer acquired the patent for Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis in 2021.