Total recall 6000 years (10)

By: James V. Kohl | Published on: November 6, 2023

Re: Cytochrome c nitrite reductase from the bacterium Geobacter lovleyi represents a new NrfA subclass 6/9/20.

This links sunlight and humidity to the pH-dependent Creation of all biodiversity on Earth via protection from the virus-driven degradation of mRNA at the origin of life.

No experimental evidence of top-down quantum causation, coherently organized biology, and no model organisms link the origin of life to more than 6000 years of ecological adaptations. Thus, the total recall of events that occurred in our past extends to experimental evidence across only 6000 years.

See for instance: Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants 11/28/12

“The findings confirm their earlier work suggesting that the majority of variants, including potentially harmful ones, were picked up during the past 5,000–10,000 years.”

and How purposeless physics underlies purposeful life 10/4/23

Assembly theory can describe all this in principle, because it is such a general framework. But organisms become what they are through complex, context-dependent developmental processes. The emergent nature of these processes is key to survival and hence to evolutionary outcomes. The important question is to what extent concepts such as assembly index, copy number and pathways through assembly space can usefully be applied in practice to such complex contexts, such as how gene regulatory networks function to control protein synthesis.

“Perhaps the roundworm (Caenorhabditis elegans) could be used to explore this more; its genome is fully known13. Each and every adult roundworm has precisely the same number of cells (apart from sex cells), and the history of every one of these cells is known, providing a basis for an assembly-theory analysis. It would seem ideal for taking the project further.”

Re: Structural factors linked to the analysis of assembly theory during the past 6000 years. See: The Structure Basis of Phytochemicals as Metabolic Signals for Combating Obesity 6/13/22 Integrative neurocircuits that control metabolism and food intake 9/23/23, The structural and functional complexity of the integrative hypothalamus 10/26/23, and miRNAs 164,361 results

For reasons that biologically uninformed theorists refuse to debate about facts linked to nutrient-dependent pheromone-regulated genetic processes of ecological adaptations via miRNA-mediated cause and effect, see:

Are you “Conflict Averse?” Bo Seo | Good Arguments: How Debate Teaches Us to Listen and Be Heard 6/14/22 and Mesenchymal stem cell-regulated miRNA-mRNA landscape in acute-on-chronic liver failure 11/4/23

Remember, all aspects of biophysically constrained life are linked from the miRNA-mRNA balance to all biodiversity via stem cell Creation in the context of links from sunlight and humidity to pH-dependent Cellulose for ages 14+ and the claims of George FR Ellis in Top-down causation and quantum physics 10/22/18

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