Microecologically constrained viruses (10)

By: James V. Kohl | Published on: July 3, 2024

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In the USA, 7/4/24 will be the next day we celebrate our independence with projectiles fired into the sky that link God’s Creation of energy-as-information to all biodiversity on Earth via the physiology of reproduction across kingdoms and Biblical Genesis. For details, see:

Exploring the landscape of miRNA production and the structural rules that shape it 7/2/24

“Degradome sequencing of semi-active DCL1 mutants separates true miRNAs from DCL1-independent small RNAs in Arabidopsis thaliana and illustrates the processing pattern of 147 pri-miRNAs. In parallel, DMS-MaPseq decodes the in vivo secondary structures of pri-miRNAs, enabling a better understanding of cleavage modes and of the impact of DCL1 cofactors on cleavage.”

That fact destroys the theories of wanna-be truth-tellers who failed to link the lab-based fixation of 4 amino acid substitutions at the SARS-CoV-2 furin cleavage site to the creation of the COVID-19 pandemic nonsense.

The facts that linked fixation two amino acid substitutions to the end of the 1918 Spanish influenza pandemic were placed into the context of light-activated miRNA biosynthesis and biophysically constrained virus driven pathology across kingdoms via the claims in Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections 4/23/20 and Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20.

With the exception of former President Donald Trump, few people realize that God’s Creation of sunlight and humidity at the origin of life link the ability of dogs to sniff out intramolecular proton transfer, which links “Selective fluoride sensing by a novel series of lanthanide-based one-dimensional coordination polymers through intramolecular proton transfer” 4/9/24 from the energy-dependent photophysical response of one-dimensional coordination polymers (CPs) and quantum annealing from electron spin to “Visualizing a protonated RNA state that modulates microRNA-21 maturation” 10/26/20 via the aurora borealis.

Most people have not kept up with the facts from Keeping up with the miRNAs: current paradigms of the biogenesis pathway 8/12/22. They have not liked sunlight and humidity from plant growth to morphological and behavioral diversity via gene expression. See: Large-scale gene expression alterations introduced by structural variation drive morphotype diversification in Brassica oleracea 2/13/24

When all is said that can be said about biologically uninformed theorists and other moronic fools, intelligent people will still be able to read the extant literature and link miRNA biogenesis to protection from the virus-driven degradation of mRNA and all pathology. For instance, see: Are miRNAs applicable for balancing crop growth and defense trade-off? 7/2/24 and Prediction of Potential miRNA-Disease Associations Based on a Masked Graph Autoencoder 7/2/24

Until then, don’t have a virus-driven heart attack. See: Endothelial Autophagy Promotes Atheroprotective Communication Between Endothelial and Smooth Muscle Cells via Exosome-Mediated Delivery of miR-204-5p 7/3/24

Have a happy Independence Day, and remember those who fought for it. See also: Combating Evolution to Fight Disease 3/7/14