Experience-based reality and PTSD (9)

By: James V. Kohl | Published on: July 24, 2024

Re; Endogenous Glutathione-Activated Nucleic Acid Molecular Circuitry for Cell-Specific MicroRNA Imaging 7/23/24

“…the endogenously responsive HCR circuit established a link between the small regulatory factors and miRNA, thereby enhancing the signal gain. In summary, the endogenously activatable DNA circuit represents a versatile toolbox for robust bioanalysis and exploration of potential signaling pathways in living cells.”

It links God’s light-activated ATP-dependent Creation of RNA at the origin of life from pH-dependent oxidative phosphoryation and peptide synthesis to all biodiversity via RNA-peptide interactions in the context of

1) Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20,

2) Morphological changes of olfactory bulbs and grooves: initial report of supernumerary olfactory bulbs 7/19/12 and

3) cancer prevention and/or effective treatment via PathBot: A Radiology-Pathology Correlation Dashboard 4/3/17 and

4) 174,003 results from today’s search for miRNAs.

My friend David Proffitt offered to pray with me for relief from Trump-assassination attempt-induced PTSD. Obviously, he prayed for me after he left. The next thing I saw was “Study identifies epigenetic ‘switches’ that regulate the developmental trajectories of single cells” (7/15/24) The finding supports my life’s work on prevention of virus-driven diseases and my detailed model.

See also: DMF-DM-seq: Digital-Microfluidics Enabled Dual-Modality Sequencing of Single-Cell mRNA and microRNA with High Integration, Sensitivity, and Automation 7/22/24

God’s Creation of energy-dependent electron spin at the origin of life links the aurora borealis to prevention of all virus-driven diseases via “…single-cell isolation, lysis, component separation, and simultaneous sequencing library preparation of mRNA and miRNA within a single DMF device.”

“DMF-DM-seq revealed differential expression patterns of single cells of noncancerous breast cells and noninvasive and aggressive breast cancer cells at both mRNA and miRNA levels.”

The authors unraveled “…tumor growth and metastasis-associated biological processes enriched by miRNA-targeted genes, along with important miRNA-interaction networks involved in significant signaling pathways.”

They also deconstructed “…the miRNA regulatory mechanisms underlying different signaling pathways across different breast cell types. In summary, DMF-DM-seq offers a powerful tool for a comprehensive study of the expression heterogeneity of single-cell mRNA and miRNA, which will be widely applied in basic and clinical research.

For comparison, curiosity was once linked to questions about the miRNA-mediated regulatory mechanisms. The curiosity was twice removed by big bang theory and neo-Darwinian evolutionary theory in The existence of nothing. which has repeatedly been linked to the overwhelming ignorance of theorists.

For contrast, researchers from Brazil and from Georgetown University (USA) would like you to learn more about biophysically constrained viral latency, healthy longevity, and cancer prevention across kingdoms. See: MicroRNAs role in telomere length maintenance and telomerase activity in tumor cells 7/23/24

Theorists would rather you suffer unnecessarily and die prematurely from the virus-driven degradation of mRNA.


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