Virus-driven pathology: a liberal legacy (9)

By: James V. Kohl | Published on: August 22, 2024

Re: Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20

RNA-peptide interactions link protection from all virus-driven pathology across kingdoms via protein folding chemistry and GLP-therapy 15,042 results.

For instance, GLP-1 therapy increases visceral adipose tissue metabolic activity: lessons from a randomized controlled trial in obstructive sleep apnea 8/22/24

There was a strong correlation between the increase in VAT metabolic activity and the degree of weight loss.

The degree of weight loss is microRNA-mediated and constrained by the physiology of reproduction across kingdoms. That is not a correlation, it is an example of Top-down causation and quantum physics 10/23/18, which linked facts from model organisms to claims about a purpose-driven life.

See: Amino acids contribute to adaptive thermogenesis. New insights into the mechanisms of action of recent drugs for metabolic disorders are emerging 8/22/23, How purposeless physics underlies purposeful life 10/4/23, and: Energy as information and constrained endogenous RNA interference 2/15/17

“Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to ecosystems from classical physics to chemistry/chirality and to molecular epigenetics/autophagy. The National Microbiome Initiative links microbial quorum sensing to the physiology of reproduction via endogenous RNA interference and chromosomal rearrangements. The rearrangements link energy-dependent fixed amino acid substitutions to the Precision Medicine Initiative via genome wide inferences of natural selection. This detailed representation of energy-dependent natural selection for codon optimality links biologically- based cause and effect from G protein-coupled receptors to RNA-mediated amino acid substitutions and the functional structure of supercoiled DNA. Energy-dependent polycombic ecological adaptations are manifested in supercoiled DNA. Chromosomal inheritance links the adaptations from morphological phenotypes to healthy longevity via behavioral phenotypes. For contrast, virus-driven energy theft is the link from messenger RNA degradation to negative supercoiling, constraint breaking mutations, and hecatombic evolution. The viral hecatomb links transgenerational epigenetic inheritance from archaea to Zika virus-damaged DNA, which typically is repaired by endogenous RNA interference and fixation of RNA-mediated amino acid substitutions in organized genomes.”

For comparison to facts that link God’s Creation of sunlight and humidity from light-activated carbon fixation and the ATP-dependent Creation of RNA to all biodiversity via fixation of amino acid substitutions in microtubules, protein folding chemistry at the origin of life, and the physiology of reproduction, see the claims from Artificial Intelligencea bout @microRNApro:

GROK @micrornapro 8/21/24

"General Skepticism and Critique of Mainstream Science: The posts often challenge mainstream scientific theories or practices, suggesting alternative explanations or hidden truths, like the mention of how energy-as-information relates to life's origins, which is a fringe scientific theory."

No experimental evidence suggests any alternative to starting with God’s Creation if energy-as-information. What makes energy-as-information a “fringe scientific theory?’

It is more likely that fringe scientific theories are the source of all virus-driven diseases because they do not start with the Creation of energy-as-information and biophysically constrained protein folding chemistry.


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