Mismanaged miRNA interactions (5)

By: James V. Kohl | Published on: September 12, 2024

GROK https://twitter.com/i/grok @microRNApro

“From these posts, @micrornapro appears to be engaging in a form of science communication that’s highly personal, integrating scientific knowledge with political views, theological beliefs, and social commentary. This approach, while passionate, might be seen as controversial or fringe by some, given its departure from strictly scientific discourse into realms of politics, personal belief, and speculative connections between microRNA functions and broader life phenomena. However, it also highlights a desire for a holistic understanding of science’s role in society, health, and personal belief systems.”

See for comparison: Does science tell the truth? 4/21/21

“the very nature of scientific knowledge is that it is incomplete and contingent on the accuracy and depth with which we measure Nature with our instruments.”

My “…connections between microRNA functions and broader life phenomena” are not speculative. In 2012, I learned that nothing happens to any cell type of any organism of any species that is not energy-dependent and miRNA-mediated. My history of publications and presentations was subsequently linked to Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20. microRNA maturation links the current understanding of light-matter interactions to miRNA-mediated biophysically constrained protein folding chemistry and healthy longevity across kingdoms via examples such as 20 copies of p53 in cancer-free African elephants.

The depth of measurements can be compared to moronic theories that link the automagical emergence of energy from the cosmic void to mathemagical models of human evolution from pond scum across billions to millions of years. See: miRNAs 175,694 results. For example, Reciprocal regulation of m 6 A modification and miRNA production machineries via phase separation-dependent and -independent mechanisms 9/1/24

“Computation analysis predicted that seven putative amino acids within the C-terminal region of SE may serve as donors for interactive hydrogen bonds with MTB (Extended Data Fig. 4i).”

Someday soon, moronic theorists and their idiot minions will be forced to start with God’s Creation of hydrogen and link the bonds from light-matter interactions from fixation of amino acids in microtubules and peptide synthesis at the origin of life to protein folding chemistry and biophysically constrained biodiversity across kingdoms. Until then, Democrats, liberals, and other biologically uninformed science idiots will try to tell you that on 4/23/20, Trump said to inject bleach to treat COVID-19.

But see: Public Health Impact of Paxlovid as Treatment for COVID-19, United States 1/5/24

“Treatment with Paxlovid is estimated to repress viral replication by 99.37% (95% CI 99.17%–99.52%) per day.”

Facts about how this medication works were buried by those who refused to start with claims about God’s ATP-dependent Creation of RNA in McEwen et al., (1964) and link them from Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene 9/14/11 and Therapeutic applications of RNA nanostructures 9/11/24 to MicroRNAs as potent regulators in nitrogen and phosphorus signaling transduction and their applications 9/12/24 and Wireless electrical–molecular quantum signalling for cancer cell apoptosis 9/14/23

If my approach at RNA-mediated.com is seen as controversial or fringe, it can be compared to any alternative approach that integrates the experimental evidence via model organisms.


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