Is the nucleotide conserved? (6)

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Moronic theorists believe that energy automagically emerged from the cosmic void and that people mathemagically evolved from pond scum during billions to millions of years. They missed the experimental evidence that links light-matter interactions at the origin of life from miRNA biogenesis to the claims about protein folding chemistry in the 2024 Nobel Prizes for Physics, Chemistry, and Medicine, and facts from Host combats porcine reproductive and respiratory syndrome virus infection at non-coding RNAs level 10/15/24

For instance see: Table 1. Host miRNAs directly target the viral genome

“The innate immune response serves as the first line of defense against viral infections, involving the activation of multiple antiviral signaling pathways and the activation and expression of antiviral factors.”

“A single miRNA can target multiple mRNAs simultaneously, and one mRNA can be regulated by several different miRNAs [Citation139]. This intricate network implies that therapeutic modulation of miRNA levels may have complex effects that vary depending on the microenvironment. The specific roles of miRNAs are further influenced by a variety of protein–protein and protein–RNA interactions within different contexts [Citation140]. Furthermore, the uptake of miRNA mimics and inhibitors by different organs can result in unpredictable side effects [Citation141]. Nonetheless, employing tissue-specific miRNAs to restrict vector tropism can be tailored to enhance specificity without diminishing efficacy [Citation142].”

Q: How do hosts tissue-specific miRNAs evolve to restrict virus-driven vector tropism?

A: In November 2012, I learned that nothing happens to any cell type in any individual of any species outside the context of energy-dependent miRNA-mediated cell type differentiation. I was somewhat embarrassed by the fact that everyone in the room of ~200 experts already new that.

See also: mirnas and Ben-jacob e 10 results mirnas and mcewen bs 2 results and “The Darwin Code“

The acronym HERV–human endogenous retrovirus–became my mantra. In 1997 and 1998, I searched the literature (and the internet) for more articles about these ancient curiosities–and located a few pieces here and there, occasional mention in monographs, longer discussions in a few very specialized texts. I was especially appreciative of the treatment afforded to HERV in the Cold Spring Harbor text Retroviruses, edited by Drs. Coffin, Varmus, and Hughes. But to my surprise, the sources were few, and there was no information about HERV targeted to the general layman.
As a fiction writer, however, I was in heaven–ancient viruses in our genes! And hardly anyone had heard of them.

The fact that food energy biophysically constrains pheromone-regulated viral latency was apparent when Richard P. Feynman placed it into the context of human idiocy touted by theoretical physicists with mathematical models. See: Richard Feynman on units of energy. For an update, see:

“The food people eat affects the health of their future generations” 10/2/24

See for comparison: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems (2018)

This angstroms to ecosystems model of ecological adaptation links nutrient energy-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA/messenger RNA balance and chromosomal rearrangements via the physiology of reproduction in species from microbes to humans.

Remember, your government, science journalists, and those who profit from censorship and misinformation are under no obligation to tell you the experimentally established scientific truth about energy-dependent miRNA-mediated biophysically constrained viral latency across kingdoms. Many, if not all of them will use their skills to prevent you from learning the truth about God’s Creation.

But see: Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections 4/23/20 and Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20

“We propose a model revisiting the architecture of RNA-peptide interactions at the origin of life…”

Thank God, pattern recognition at the level of nutrient-dependent RNA-peptide interactions led to the claims about energy-dependent miRNA-mediated healthy longevity. Healthy longevity links the 2024 Nobel Prizes in Physics, in Chemistry and in Physiology or Medicine to the claims of George FR Ellis in How purposeless physics underlies purposeful life 10/4/23.

However, an attempt was made to redefine the Laws of Physics to fit moronic theories. That led Ellis to suggest that Caenorhabditis elegans be used to explore the facts because

1) its genome is fully known, and

2) each adult roundworm has precisely the same number of cells (apart from sex cells).

The history of cell type differentiation in each of these cells is known to be nutrient-dependent and pheromone regulated across species, which provides a basis for an assembly-theory analysis that seems ideal for taking the new assembly project further.

But the assembly project can then no longer be referred to as an assembly theory. It is an example of God’s Creation of energy-dependent biodiversity that extends to facts about protein folding chemistry in cancer-free African elephants with 20 copies of p53 that protect them from virus-driven cancers, and to effective miRNA-mediated treatment of malignant brain tumors (gliomas).

See also: Nanoplatelets modified with RVG for targeted delivery of miR-375 and temozolomide to enhance gliomas therapy 10/15/24

“…the nanoplatelets were modified with central nervous system-specific rabies viral glycoprotein peptide [which links] this multifunctional ‘natural’ nanodrug delivery system provides a potent, scalable, and safety approach for platelet-based combined cancer chemotherapy and gene therapy.”

Look how far cancer researchers have come since researchers abandoned theories in the late 1990s. Experimental evidence led to the report that Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene 9/2/11.

Never forget, biologically uninformed science idiots, Trump-haters, and their idiot minions did not want you to know about effective miRNA-mediated treatment of all virus-driven pathology because the effective treatments are linked God’s Creation of sunlight and humidity at the origin of life, not billions to millions of years of natural selection for beneficial mutations.

GROK @microRNApro AI update 10/15/24

Given the date and context, if @micrornapro is active around October 2024, posts might also reflect on recent advancements or publications in the field, possibly linking miRNAs to current health issues or breakthroughs in biotech applications, all while maintaining a critical lens on how these are reported or understood in broader scientific circles.

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