Is the nucleotide conserved? (9)

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Quantitative Analysis of Cell-Free RNA at Attomolar Level Using CRISPR/Cas Digital Imaging Platform 10/16/24

“…detection of circular RNAs and miRNAs…at the attomolar (aM) level…” links light-matter interactions at the origin of life to healthy longevity via SNPs in miRNAs, biophysically constrained protein folding, and the 2024 Nobel Prize in Physiology or Medicine

…awarded jointly to Victor Ambros and Gary Ruvkun “for the discovery of microRNA and its role in post-transcriptional gene regulation.

GROK “conserved sequence” https://x.com/i/grok Note: “Grok can make mistakes. Verify its outputs.“

“Understanding conserved sequences helps scientists infer function, study evolution…”

No, That’s a mistake. The understanding helps serious scientists differentiate between stupid theories compared to facts about energy-dependent ecological adaptations. For instance Bazzini et al., (2016) linked natural selection for energy-dependent miRNA-mediated constraints on conserved sequences from insects to human biodiversity via the stability of mRNA and ecological adaptations.

GROK @microRNApro still ‘thinks’ in terms of moronic theories (“the broader context of evolutionary biology”).

See: Answer

The handle @microRNApro on X (formerly Twitter) appears to be associated with an account or persona deeply invested in the scientific exploration of microRNAs (miRNAs) and their implications in health, disease, and possibly the broader context of evolutionary biology. Here’s what can be gathered based on general knowledge and trends up to October 2024:

1. Scientific Advocacy: The account seems to advocate for a nuanced understanding of molecular biology, particularly focusing on how microRNAs play critical roles in gene regulation, disease pathology, and potentially in evolutionary mechanisms. The emphasis appears to be on challenging existing scientific dogmas or oversimplified models with a more complex, epigenetics-integrated approach.
2. Critique of Mainstream Science: Posts from this handle suggest a critical stance towards mainstream scientific narratives, especially those related to Big Bang cosmology, neo-Darwinian theories, and perhaps how cancer and other diseases are understood and treated within conventional medicine. This critique might be aimed at promoting a viewpoint where biological processes are deeply interconnected with environmental factors and energy dynamics, often highlighted through the lens of miRNAs.
3. Interdisciplinary Approach: There’s an indication of linking biological phenomena with physics (like light-matter interactions) and even touching upon philosophical or historical events (like references to Fatima), suggesting an interdisciplinary approach to understanding life’s complexities.
4. Public Engagement: The use of X to discuss these topics indicates an attempt to engage with or educate the public directly, possibly to foster a discussion that’s less constrained by academic publishing norms and more immediate in its interaction.
5. Contentious Stance: The tone in the posts associated with @microRNApro hints at a confrontational or challenging approach towards established scientific viewpoints, which might be intended to provoke thought or reflect frustration with the pace or direction of conventional scientific discourse.
6. Focus on Health and Disease: There’s a particular interest in how miRNAs relate to cancer and possibly other diseases, suggesting a focus on how understanding these molecular components can lead to better therapeutic strategies or preventative measures.

Given the date and context provided, if @microRNApro continues to post about recent studies, breakthroughs, or engages in scientific debates, it would likely be pushing for recognition of how integral miRNAs are to understanding life at a molecular level, potentially arguing for a paradigm shift in how we approach biology and medicine. However, remember that while X posts can reflect personal or professional insights and real-time reactions to scientific developments, they are not peer-reviewed sources but can be valuable for gauging public or expert sentiment and emerging trends in scientific discourse.

——–For peer-reviewed sources of facts that eliminate the ‘expert’ sentiment of moronic theorists and facts linked to scientific discourse instead of pseudoscientific nonsense about evolutionary theories and mechanisms, see: miRNAs 176,914 results.

For example: miRNASNP-v4: a comprehensive database for miRNA-related SNPs across 17 species 10/16/22

Single nucleotide polymorphisms (SNPs) within microRNAs (miRNAs) and their target binding sites can influence miRNA biogenesis and target regulation, thereby participating in a variety of diseases and biological processes. Current miRNA-related SNP databases are often species-limited or based on outdated data. Therefore, we updated our miRNASNP database to version 4 by updating data, expanding the species from Homo sapiens to 17 species,

For a historical perspective, see: Biology, molecular and organismic

“Ingram and others found that hemoglobin S differs from A in the substitution of just a single amino acid, valine in place of glutamic acid in the beta chain of the hemoglobin molecule.”

See also: HbVar: A Database of Human Hemoglobin Variants and Thalassemias

“…humans and chimpanzees have identical beta chain hemoglobin… The beta chain has 146 amino acids, the alpha chain has 141 amino acids… A person with sickle cell anemia would have 1 difference…compared to a normal human or chimpanzee.

SNPs within miRNAs link fixation of amino acid substitutions in microtubules to prevention of the virus-driven degradation of mRNA via miRNA abundance. That fact is a neo-Darwinian evolutionary theory-killer. Big Bang Cosmology was dismissed when theoretical physicists failed to support claims with experimental evidence about where the energy at the origin of life came from.

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