miRNA-mediated hierarchy of needs (3)

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mirnas 177,016 results

Effects of intrauterine extracellular vesicle microRNAs on embryonic gene expression in low-fertility cows 10/19/24 links light-matter interactions at the origin of life to protection from virus-driven fescue toxicosis via our 1996 review of cell type differentiation From Fertilization to Adult Sexual Behavior.

We used the term pre-mRNA, which was changed in 2018 to miRNA by the 2024 Nobel Prize Winners in Physiology or Medicine, after I published Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18.

This angstroms to ecosystems model of ecological adaptation links nutrient energy-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA/messenger RNA balance and chromosomal rearrangements via the physiology of reproduction in species from microbes to humans.

I’ve not been told by any intelligent serious scientist what I left out.

Most of them know that Clinical implications of miRNAs in erythropoiesis, anemia, and other hematological disorders 10/18/24 links experimentally established facts across kingdoms via theromodynamic cycles of protein folding chemistry that also link A general empirical model of protein evolution derived from multiple protein families using a maximum-likelihood approach 5/1/01 and A thermodynamic model of protein structure evolution explains empirical amino acid substitution matrices 7/4/21 via:

“selection for thermodynamically stable proteins, coupled with nucleotide mutation bias filtered by the structure of the genetic code, is the primary driver behind the global amino acid substitution patterns observed in proteins throughout the tree of life.”

For comparison to moronic claims in models of protein ‘evolution’ or obscure claims about amino acid substitution matrices, you can start with the refutation of pseudoscientific nonsense touted in A universal trend of amino acid gain and loss in protein evolution 1/19/05

Amino acid composition of proteins varies substantially between taxa and, thus, can evolve.

The composition of amino acids in proteins did not ‘evolve.’ All experimental evidence supports the claims linked to fixation of amino acid substitutions in microtubules and energy-dependent miRNA-mediated ecological adaptions linked to healthy longevity across kingdoms. If not for the bastardization and obfuscation of facts about biophysically constrained viral latency and healthy longevity, billions of dollars and millions of lives could have been saved during the coronavirus pandemic via use of fast-acting drugs like Paxlovid. See: Public health impact of Paxlovid as treatment for COVID-19 1/5/24

“…fast-acting antiviral drugs like Paxlovid can serve as invaluable tools to mitigate COVID-19 epidemics.”

Intelligent serious scientists learned how to mitigate the effects of viruses on the degradation of mRNA via diet and the pheromone-regulated physiology of reproduction which were reported in Museum für Naturkunde Explores Maria Sibylla Merian’s Legacy and Editions of Her Metamorphosis as “The Wondrous Transformation of Caterpillars and their Remarkable Diet of Flowers” (1679) and as Darwin’s “conditions of life” in 1859. See chapters 4, 5 and 6.

To move forward after hundreds of years of pseudoscientific nonsense touted by moronic theorists, see also: Construction of an interactome network among circRNA-miRNA-mRNA reveals… 10/18/24 facts linked to Unraveling aging from transcriptomics 10/17/24 by intelligent serious scientists who linked energy-dependent miRNA abundance from God’s Creation of light-matter interactions at the origin of life from sunlight and humidity to peptide synthesis at the origin of life via biophysically constrained protein folding chemistry across kingdoms.

See also: Prefrontal TNRC6A mediates anxiety-like behaviour by regulating CRF through the maintenance of miR-21-3p stability. 10/16/24 and The p53/miRNA Axis in Breast Cancer. 10/18/24

If you follow the experimental evidence that links light-matter interactions at the origin of life to miRNA-mediated light-odor biophysically constrained protein folding chemistry and behavior, you can help prevent or effectively treat all virus-driven diseases. If you prefer moronic theories, you will help to cause them. Follow the scientific progress reported on miRNAs, and help to save someone you love, or learn who killed them.

See also: “…insights from nematodes, zebrafish, and Drosophila” It links Ben Feringa’s 11/20/18 claim “2013 was the year in which prophesy from the bible became reality.” to all biodiversity on Earth via energy-dependent miRNA abundance.

Be the polymath. End the pseudoscientific nonsense touted by theorists. Link light-matter interactions at the origin of life from epigenetic effects of sunlight to light-odor biophysically constrained affects on hormones and behavior across kingdoms via H2O.

Visualize this! “Visualizing a protonated RNA state that modulates microRNA-21 maturation” 11/23/19 It predicted full support for Trump’s 4/23/20 claim that light-matter interactions, conditions of life, and optimal nutrition link sunlight and humidity to protection from the virus-driven degradation of mRNA and diseases across kingdoms.

Don’t forget to eat nutritious foods, get some exercise and drink plenty of water. Forget the stupid theories.

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