miRNA-mediated hierarchy of needs (8)

By: James V. Kohl | Published on: October 23, 2024

Re: Epigenetic modulation of autophagy pathway by small molecules in colorectal cancer: a systematic review 10/23/24

“…recognition of the epigenetics mechanism of anticancer small molecules on autophagy…”

This level of recognition links the 2024 Nobel Prizes in Physics, Chemistry and in Physiology or Medicine to effective cancer treatments with microtubule inhibitors via RNAi and The biology of water homeostasis10/21/24, which links light-matter interactions at the origin of life to all biodiversity on Earth via:

  1. the potential of hydrogen (pH),
  2. the ATP-dependent Creation of RNA in regulatory T cells,
  3. fixation of amino acid substitutions in microtubules,
  4. the weekend resurrection of the bacterial flagellum in P. fluorescens knock outs,
  5. effective cancer treatment with microtubule inhibitors and
  6. what is known to all intelligent serious scientists about GLP-1 receptor agonists and SGLT-2 Inhibitors in the context of Type 2 diabetes. See: SGLT-2 Inhibitors and GLP-1 Receptor Agonists in Type 2 Diabetes: BMJ Rapid Recommendation (2022).

You could place the biology of water homeostasis into the evolution of all biodiversity, if you linked it to the automagical emergence of energy from the cosmic void and mathemagical models that have never been supported with experimental evidence. However, the experimental evidence links top-down quantum coherence to coherently organized biology via this model of Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18

“This angstroms to ecosystems model of ecological adaptation links nutrient energy-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA/messenger RNA balance and chromosomal rearrangements via the physiology of reproduction in species from microbes to humans. The nutrient-dependent pheromone-controlled changes are required for the thermodynamic regulation of intracellular signaling, which enables biophysically constrained nutrient-dependent protein folding; experience-dependent receptor-mediated behaviors, and organism-level thermoregulation in ever-changing ecological niches and social niches.”

If you are content to watch biologically uninformed Democrats, atheists, and Trump-hating liberals ignore the claims from my model and Trump’s 4/23/20 claim that sunlight and humidity weaken coronavirus replication, prepare for a future in which your basic needs for food and water are provided by your government (or not).


Subscribe
Notify of
guest
0 Comments
Oldest
Newest Most Voted
Inline Feedbacks
View all comments

Want more on the same topic?

Swipe/Drag Left and Right To Browse Related Posts: