Trump & Soon-Shiong secure the media (4)

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After “Nature” endorsed Kamala Harris, “Endogenous self-peptides guard immune privilege of the central nervous system10/30/24 linked Trump’s 4/23/20 claims from optimal nutrition to energy-dependent miRNA-mediated constraints on coronavirus replication and cancer via Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20 and everything known to intelligent serious scientists about prevention of virus-driven diseases across kingdoms via “…the architecture of [light-matter] RNA-peptide interactions at the origin of life….”

A report on Biomolecular condensates mediate bending and scission of endosome membranes 10/9/24 was published on 10/30/24 as Cell membranes shaped and cut by phase-separated liquid protein condensates after light-matter interactions were linked to every aspect of biophysically constrained biodiversity on Earth by the physiology of reproduction and fixation of amino acid substitutions in microtubules for ages 14+ in Cellulose: A Plant Cell Biology Game.

However, when I checked GROK AI on 10/30/24, it still reported there was no direct evidence that linked light-matter interactions to all biodiversity on Earth via the physiology of reproduction in Biblical Genesis.

See: Do light-matter interactions directly link miRNAs to all biodiversity on Earth via protein folding chemistry and the physiology of reproduction in species from cyanobacteria to cancer-free African elephants.

Answer: “Other genetic, environmental, and evolutionary factors are equally important in the grand tapestry of life’s diversity.”

The idea that light-matter interactions directly link miRNAs (microRNAs) to all biodiversity on Earth through protein folding chemistry and reproductive physiology across various species involves several layers of biological processes:

1. Light-Matter Interactions: Light plays a crucial role in biology, particularly in photosynthesis in organisms like cyanobacteria. This interaction can influence gene expression, potentially including miRNAs, by affecting cellular energy dynamics and signaling pathways.
2. MicroRNAs (miRNAs): miRNAs are small non-coding RNA molecules that regulate gene expression post-transcriptionally. They can affect protein synthesis by binding to messenger RNA (mRNA), leading to either the degradation of mRNA or the inhibition of translation. This regulation can influence a myriad of cellular processes, including development, differentiation, and response to environmental changes.
3. Protein Folding Chemistry: Proteins must fold into specific three-dimensional structures to function correctly. The folding process is influenced by various factors, including the cellular environment (like pH, temperature, and molecular chaperones) which can be indirectly affected by light through its impact on cellular metabolism and energy availability. miRNAs could potentially regulate proteins involved in this folding process or be involved in stress responses related to protein misfolding.
4. Physiology of Reproduction: miRNAs are known to play roles in reproductive processes across species. For example, they can affect gametogenesis, embryonic development, and sex determination. In the case of African elephants, which are noted for their resistance to cancer, this could involve miRNAs influencing cellular pathways like those involving tumor suppressors (e.g., p53), which might be linked to their evolutionary adaptations.
5. Linking Biodiversity: The suggestion that these interactions directly link miRNAs to all biodiversity might be an overstatement in terms of direct causality. However:
   • Direct Effects: miRNAs directly influence gene expression, which impacts how organisms adapt to their environments, possibly influencing speciation and biodiversity through evolutionary pressure on gene regulation.
   • Indirect Effects: Light influences ecological systems, which indirectly affects biodiversity through photosynthesis, circadian rhythms, and other light-dependent processes that might impact miRNA regulation.

Critical Examination:

• Complexity: The biological systems are complex with many interacting components. While light can initiate a cascade of events, the direct linkage from light to miRNAs to biodiversity through protein folding and reproduction oversimplifies a network of biological interactions.
• Evolutionary Perspectives: From an evolutionary viewpoint, miRNA regulation might indeed contribute to biodiversity by fine-tuning gene expression, but this is one of many mechanisms. Environmental factors, genetic drift, mutations, and other regulatory mechanisms also play significant roles.
• Evidence and Debate: While there’s research showing miRNAs’ roles in various biological processes, the claim of a singular, direct link from light-matter interactions to all biodiversity via miRNAs seems to stretch the current scientific consensus. There’s certainly an interaction, but describing it as the sole or direct cause for biodiversity across all species might not hold up under rigorous scrutiny due to the multitude of other genetic and environmental influences.

In summary, while miRNAs, influenced by light-matter interactions, play a significant role in cellular regulation, which in turn affects protein folding and reproductive physiology, claiming this as the direct and sole mechanism linking to all biodiversity would be an oversimplification. Other genetic, environmental, and evolutionary factors are equally important in the grand tapestry of life’s diversity.

For comparison to irrelevant theories that are not supported by experimental evidence, see also: miRNAs 177,380 results, with this addition Hierarchical hypergraph learning in association-weighted heterogeneous network for miRNA-disease association identification 10/30/24

“…HHAWMD has better performance and can be used as a powerful tool for miRNA-disease association identification.”

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