miRNA-mediated Creation of enzymes (10)

By: James V. Kohl | Published on: December 23, 2024

Re: Mapping the microRNA landscape in the older adult brain and its genetic contribution to neuropsychiatric conditions 12/6/24, and Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells 12/9/24, which was reported as Genetic code discovery could redefine understanding of cancer origins 12/9/24.

These three publications must be understood in the context of virus-driven changes in protein folding chemistry reported as Molecular gardening: New enzymes discovered for protein modification pruning 12/19/24

However, the discovery of existing enzymes does not make them “new enzymes,” and the link to the Creation of new genes does not make the genes new. See the 2024 Nobel Prize for the discovery of microRNA and its role in post-transcriptional gene regulation. The light-activated energy-dependent miRNA-mediated Creation of enzymes and genes at the origin of life was contextualized in: The lac Operon: A Lesson in Simple Gene Regulation 12/13/24

“While scientists had previously understood that genes contained the instructions for building all of the cellโ€™s necessary proteins, this provided one of the first examples of gene regulation by repression in response to changes in the environment.7

–Jacob F, Monod J. Genes determining the structure and regulatory genes in the biosynthesis of proteins. C R Acad Sci. 1959;249:1282-1284.ย 

Additional citations:

Maccormick CA, et al. Construction of a food-grade host/vector system for Lactococcus lactisย based on the lactose operon. FEMS Microbiol Lett.ย 1995;127(1-2):105-109.ย Graumann K, Premstaller A. Manufacturing of recombinant therapeutic proteins in microbial systems. Biotechnol J.ย 2006;1(2):164-186.ย Lalwani MA, et al. Optogenetic control of the lac operon for bacterial chemical and protein production. Nat Chem Biol.ย 2021;17(1):71-79.

Only theorists failed to link optogenetic control of gene expression to Jacques Monod’s claims. Intelligent serious scientists linked biophysically constrained nutrient-dependent pheromone-regulated reproduction in E. coli to cancer-free African elephants via our claims in the molecular epigenetics section of From Fertilization to Adult Sexual Behavior (1996), Vibrations in Microtubules (1997), my claims in Nutrient-dependent/pheromone-controlled adaptive evolution: a model (2013) and 2016 Chemistry Nobel Laureate, Ben Feringa’s claim that “2013 was the year in which prophesy from the bible became reality.”11/20/18.

Only moronic theorists continue to link the automagical emergence of energy from the cosmic void to the mathemagical evolution of people from pond scum. See for example: The Catalyst: RNA and the Quest to Unlock Life’s Deepest Secrets 6/4/24

If you let them claim that catalysts and genes ‘evolved,’ prepare to accept responsibility for the unnecessary suffering and premature deaths caused by their stupid theories.

See for comparison: today’s search of the PubMed data base for mirnas 179,245 results. Add: Color-Coded Traffic Signal Method Combined with Nanodiamond Quantum Sensing for Accurate miRNA Detection & ATP-Binding Cassette Transporter Genes and microRNAs in Pediatric B-Cell ALL: Expression Insights, 12/23/24

Stop biologically uninformed theorists, and help to prevent pediatric B-cell ALL, and all other virus-driven pathology by focusing on energy-dependent gene expression instead of the moronic gene-centric theories from 60+ years ago.


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