miRNA-mediated prevention (4)

By: James V. Kohl | Published on: January 14, 2025

mirnas 180,008 results

MicroRNA-142-3p chemo-sensitizing breast cancer to docetaxel: apoptosis and cell cycle arrest induction, and migration suppression 11/15/24 indexed 1/14/25

“โ€ฆdocetaxelโ€ฆexerts its anti-cancer effects by interfering with microtubulesโ€ฆand subsequent inhibition of mitosis through the addition of tubulin molecules.”

This links energy-dependent autophagy to biophysical constraints on all virus-driven diseases via miRNA abundance and fixation of amino acid substitutions across kingdoms, and to Dr. Patrick Soon-Shiong’s patent for microtubule inhibition reported as Disrupting Cancer. 12/7/14

If you know someone who suffered unnecessarily and/or died prematurely from any virus-driven disease, ask why profiteers refuse to tell the truth about how energy-dependent cause and effect disrupts virus-driven pathology.

See also: RNA splicing variants of the novel long non-coding RNA, CyKILR, possess divergent biological functions in non-small cell lung cancer 12/5/24

I learned about this before my diagnosis. It helped me to trust my doctors with their care plan, but not with docetaxel treatment after surgical removal of my left lower lobe more than 4 years ago.

Still, the research progress has been so rapid that I got caught not knowing the difference between second and third generation “next generation sequencing.

See: MARTRE family proteins negatively regulate CCR4-NOT activity to protect poly(A) tail length and promote translation of maternal mRNA 1/2/25 reported as Study reveals new mechanism of mRNA poly(A) tail regulation in early embryos 1/14/25 and Glucose Metabolism Acts as a Compass to Guide Embryonic Development 10/18/24, and as “Monoallelic expression can govern penetrance of inborn errors of immunity” 1/1/25


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