Anti-Christian bias (9)

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Re: MiRNAs as biomarkers of nutritional therapy to achieve T2DM remission in patients with coronary heart disease: from the CORDIOPREV study 2/22/25

For the most recent example of Grok AI’s anti-Christian ideological bias, see the attempts to put facts about nutrient-dependent pheromone regulated ecological adaptations across kingdoms back into the context of moronic theories.

Compare: Explore ATP’s role in miRNA to maximum obfuscation of facts about ATP-dependent miRNA-mediated ecological adaptations in Explore virus-driven diseases

For a historical perspective, link Merian’s claims from 1679 to Darwin’s “conditions of life,” 1859 and facts that link light-matter interactions from miRNA-mRNA interactions to energy-dependent miRNA-mediated protein folding chemistry. For examples, see: 181,347 results from today’s PubMed search for miRNAs.

For a recent summary, see DeepSeek’s validation of my 2013 model: Nutrient-dependent/pheromone-controlled adaptive evolution: a model 6/14/13. Stop pretending that the Chinese are not the biggest threat to the miRNA-mediated future of humanity because they are more intelligent, know how to control protein folding chemistry, and to create novel viruses that disrupt protein folding chemistry to cause diseases.

“Link light-matter interactions to protein folding chemistry“
Yes, light-regulated humidity and pH-dependent microRNA (miRNA) biogenesis can significantly influence gene expression and development across various organisms, including microbes, plants, and animals, by modulating miRNA abundance. Here’s how these factors play a role:

1. Light-Regulated Humidity and miRNA Biogenesis Plants: Light and humidity are critical environmental factors that influence plant growth and development. Light regulates the expression of genes involved in miRNA biogenesis, and humidity affects stomatal closure and transpiration, which can indirectly influence cellular conditions like pH and redox state. These changes can alter the processing and stability of miRNAs, which in turn regulate genes involved in stress responses, development, and metabolism. Animals: While animals are less directly influenced by environmental humidity, light (e.g., circadian rhythms) can regulate miRNA expression in tissues like the retina or brain. miRNAs influenced by light can modulate genes involved in circadian clock regulation, metabolism, and behavior. Microbes: In microbes, light and humidity can affect miRNA-like small RNAs (sRNAs) that regulate gene expression in response to environmental changes. For example, in photosynthetic bacteria, light-dependent sRNAs can influence metabolic pathways and stress responses.
2. pH-Dependent miRNA Biogenesis Plants: Cellular pH can fluctuate due to environmental stressors like drought, salinity, or light intensity. These pH changes can affect the activity of enzymes involved in miRNA processing, such as Dicer-like proteins, leading to changes in miRNA abundance. This, in turn, influences the expression of target genes involved in stress adaptation and development. Animals: In animals, pH changes in cellular compartments (e.g., endosomes or lysosomes) can influence miRNA maturation and stability. For example, acidic conditions in tumor microenvironments can alter miRNA profiles, affecting cancer-related gene expression. Microbes: pH-dependent regulation of sRNAs in microbes can influence gene expression in response to environmental pH changes, such as those encountered in host-pathogen interactions or during fermentation processes.
3. Impact on Gene Expression and Development miRNA Abundance: Changes in miRNA abundance due to light, humidity, or pH can have cascading effects on gene expression. miRNAs typically bind to complementary mRNA sequences, leading to mRNA degradation or translational repression. This post-transcriptional regulation fine-tunes gene expression and is crucial for development, stress responses, and homeostasis. Cross-Organism Effects: The conservation of miRNA pathways across eukaryotes means that similar mechanisms can influence development and gene expression in microbes, plants, and animals. For example, miRNAs involved in stress responses or developmental timing often have conserved roles across species.
4. Examples Plants: miR398 is regulated by light and oxidative stress, targeting genes involved in copper homeostasis and stress responses. Animals: miR-132 is light-regulated and plays a role in neuronal plasticity and circadian rhythms. Microbes: sRNAs in bacteria like E. coli are regulated by environmental pH and influence stress response genes.

In summary, light-regulated humidity and pH-dependent miRNA biogenesis are important mechanisms that influence gene expression and development across diverse organisms by modulating miRNA abundance. These regulatory pathways help organisms adapt to environmental changes and maintain developmental precision.

MY SUMMARY: Biologically uninformed science idiots refuse to link God’s Creation of sunlight and humidity to the pH-dependent origin of life via the regulatory pathways required to maintain developmental precision. Instead, they substitute the automagical emergence of energy from the cosmic void and the mathemagical evolution of people from pond scum.

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