Meta AI vs xAI (10)

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I asked [DeepSeek] “Does light-regulated humidity and pH-dependent microRNA biogenesis significantly influence gene expression and development across various organisms, including microbes, plants, and animals via miRNA abundance?”

THE ANSWER:

Yes, light-regulated humidity and pH-dependent microRNA (miRNA) biogenesis can significantly influence gene expression and development across various organisms, including microbes, plants, and animals, by modulating miRNA abundance. Here’s how these factors play a role: (Details were added)

xAI challenged the details provided by DeepSeek, which led a battle of wits.

I wrote:

You offered support for my model at every level of investigation that has not been linked to data-driven moronic theories about the automagical emergence of energy from the cosmic void and the mathemagical evolution of people from pond scum.

If you do not start with Biblical Genesis, your anti-Christian biased theological agenda is as obvious as when “DeepSeek” started with God’s Creation of sunlight and humidity, which linked energy-as-information to the miRNA-mediated origin of pH-dependent life.

Grok’s Conclusion

Explanatory Power Clash

These data explain life’s origins, regulation, and outcomes via “moronic theories” (your term) like energy from a cosmic void and evolution from pond scum—mainstream science’s playbook. They don’t need miRNA as the linchpin, nor Genesis as the frame. Your model’s strength is its miRNA focus, tying energy to feedback loops with empirical support (e.g., miR-122, miR-17-92). Their power is broader acceptance and simpler mechanisms—no RNA-centric leap required.

The epic failure of theorists who use “mainstream science’s playbook” to link God’s Creation of UV light from constraints on the creation of new galaxies to biophysically constrained viral latency across kingdoms via the physiology of reproduction led to the clash between gene-centric pseudoscientific nonsense and experimentally established facts about RNA-centric feedback loops.

Every intelligent serious scientist I’ve met eliminated the broader acceptance and simpler mechanisms of moronic gene-centric theories with facts that led to 181,709 results in indexed works on PubMed that mention miRNAs. The articles link light-activated miRNA biogenesis at the origin of life from miRNA abundance to all biodiversity on Earth via energy-dependent RNA interference, which prevents the virus-driven degradation of mRNA and all virus-driven pathology.

For comparison, stupid theorists accept data that links gene-centric evolutionary processes to data-driven models that have no explanatory power. The data-driven models are promoted by simple-minded people who add theories to theories — none of which link energy to biophysically constrained viral latency and life across kingdoms.

See for comparison: What is life when it is not protected from virus driven entropy 3/30/16 and Energy as information and constrained endogenous RNA interference 2/15/17

AI Overview

“Energy as information and RNA interference” in the context of James Kohl refers to a theoretical concept that proposes a link between the flow of energy within a biological system and the regulation of gene expression through RNA interference (RNAi), essentially suggesting that energy can be interpreted as information that directs cellular processes by controlling which genes are expressed or suppressed through RNAi mechanisms. 

Key points about this concept:

• RNA interference as a regulatory mechanism: RNAi is a natural cellular process where small RNA molecules (microRNAs or siRNAs) bind to specific messenger RNA (mRNA) molecules, inhibiting their translation into proteins, effectively “silencing” gene expression. 

Energy as a signal:

Kohl’s theory suggests that fluctuations in energy levels within a cell can act as a signal that triggers the production of specific RNAi molecules, thereby influencing gene expression in response to environmental changes or physiological demands. 

Implications for research:

This concept could potentially lead to new insights into how cells respond to energy stress, the role of RNAi in metabolic regulation, and the development of novel therapeutic strategies targeting RNAi pathways. 

For updated facts about the origin of life and RNAi pathways, see: Bacterial immunotherapy leveraging IL-10R hysteresis for both phagocytosis evasion and tumor immunity revitalization 3/3/25

“These processes depended on high IL-10R expression in tumor-associated immune cells, highlighting the critical role of IL-10R hysteresis.”

Epigenetic effects on hysteresis (the dependence of the state of a system on its history, such as the history of life) link the Impact of Western diet on milk miRNAs and target genes in offspring adipose tissue: modulation by betaine during suckling 3/2/25 from energy-dependent biophysical constraints on fixation of trimethlyglycine/betaine in organized genomes at the origin of life to the end of claims about evolutionary perspectives in Betaine lipids: Biosynthesis, functional diversity and evolutionary perspectives 1/8/25

The levels of complexity linked to trimethlyglycine were revealed in the context of the mouse to human model of biodiversity during 5000 years of ecological adaptations in populations from East Asia to North American Indians.

Only one food energy-dependent pheromone regulated change was required to link fixation of rs3827760, also known as 1540T/C, 370A or Val370Ala — a single nucleotide polymorphism (SNP) in the ectodysplasin A receptor EDAR gene on chromosome 2, to sex differences and biophysically constrained viral latency across kingdoms from microbes to cancer-free African elephants with 20 miRNA-mediated copies of p53.

See: 2 Cell Studies Reveal Genetic Variation Driving Human Evolution 2/14/13

For comparison see: Nutrient-dependent/pheromone-controlled adaptive evolution: a model 6/14/13

“These two reports (Grossman et al., 2013; Kamberov et al., 2013) tell a new short story of adaptive evolution. The story begins with what was probably a nutrient-dependent variant allele that arose in central China…. The effect of the allele is adaptive and it is manifested in the context of an effect on sweat, skin, hair, and teeth. In other mammals, like the mouse, the effect on sweat, skin, hair, and teeth is due to an epigenetic effect of nutrients on hormones responsible for the tweaking of immense gene networks that metabolize nutrients to pheromones. The pheromones control the nutrient-dependent hormone-dependent organization and activation of reproductive sexual behavior in mammals such as mice and humans, but also in invertebrates as previously indicated. That means the adaptive evolution of the human population, which is detailed in these two reports, is also likely to be nutrient-dependent and pheromone-controlled, since there is no other model for that.”

Expect the antagonism from xAI’s Grok to continue long after the claims from DeepSeek continue to be validated in future publications that mention the link from food energy-dependent pheromone regulated miRNA abundance to ecological adaptations.

After xAI’s Grok missed facts that link sunlight and humidity to all oxygen-dependent pH-dependent biophysically constrained biodiversity on Earth via the physiology of reproduction in Biblical Genesis, it can only continue to exemplify human idiocy that extends to those who program answers from AI that are clearly only believed by other morons.

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