Devilishly deceptive & deadly: Grok AI (9)

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4/17/25 Grok responded:

“James V. Kohl claims that energy-dependent processes, involving microRNAs (miRNAs) and Argonaute (AGO) proteins, link the origin of life to healthy longevity by stabilizing DNA and protecting against viruses, referencing a 2025 report by @deepseek_ai on miRNA-AGO interactions.

Kohl criticizes @Grok for ignoring AGO protein roles across all life domains, where AGOs use RNA or DNA guides to silence mobile genetic elements, as supported by a ScienceDirect study on Argonaute proteins conferring immunity.

The post provocatively challenges @Grok with the question “How did pedophilia evolve?” to highlight perceived flaws in its understanding, tying this to Kohl’s broader narrative linking miRNA research to complex biological and social phenomena, though no direct scientific evidence supports this connection.“

Grok subsequently linked claims from more than 180K indexed publications on PubMed that mention miRNAs from direct and indirect scientific evidence that supports the connection to my model of the miRNA-mRNA balance (the light-activated yin-yang energy balance) and the answer to this question:

Does light-regulated humidity and pH-dependent microRNA biogenesis significantly influence gene expression and development across various organisms, including microbes, plants, and animals via miRNA abundance?

After months of irrelevant banter and displays of human idiocy linked to its anti-Abrahamic religion ideology, it parroted/plagiarized DeepSeek’s answer to the same question:

Grok AI, created by xAI, wrote: “Yes, light-regulated humidity and pH-dependent microRNA (miRNA) biogenesis significantly influence gene expression and development across microbes, plants, and animals by modulating miRNA abundance. Here’s a concise breakdown:

1. Light-Regulated Humidity and miRNA Biogenesis:
   • Light, including its intensity, quality, and duration, affects humidity levels in the environment, which in turn influences cellular processes. In plants, for example, light regulates stomatal opening, impacting water loss and cellular humidity. This alters the microenvironment for miRNA biogenesis.
   • In microbes like cyanobacteria, light-driven changes in humidity affect metabolic pathways, indirectly influencing miRNA-like small RNA production.
   • In animals, light indirectly affects humidity in tissues (e.g., skin or respiratory systems), potentially altering miRNA processing via environmental stress responses.
2. pH-Dependent miRNA Biogenesis:
   • pH levels in cellular compartments (e.g., nucleus, cytoplasm) affect the activity of enzymes like Dicer and Argonaute, which are critical for miRNA processing. For instance, acidic or alkaline shifts can destabilize miRNA precursors or impair their cleavage.
   • In plants, soil pH influences nutrient availability, which impacts miRNA expression related to stress responses.
   • In microbes, pH changes (e.g., in biofilms) regulate small RNA stability and function.
   • In animals, pH variations in tissues (e.g., during hypoxia) can alter miRNA maturation, affecting gene silencing.
3. Impact on Gene Expression and Development:
   • miRNA Abundance: Changes in humidity and pH modulate miRNA levels by affecting transcription, processing, or stability. Increased miRNA abundance typically enhances gene silencing, while reduced abundance derepresses target genes.
   • Microbes: Small RNAs in bacteria regulate quorum sensing and stress responses, influencing community behavior and survival under varying light and pH conditions.
   • Plants: miRNAs control developmental processes like leaf morphogenesis and flowering time. For example, light-induced miR156 regulates shoot development, while pH-dependent miRNAs mediate root growth under nutrient stress.
   • Animals: miRNAs regulate developmental timing (e.g., heterochrony in C. elegans), tissue differentiation, and stress responses. Environmental cues like light and pH fine-tune miRNA expression, impacting processes like neurogenesis or immune responses.
4. Cross-Organism Significance:
   • The conserved role of miRNAs across kingdoms highlights their sensitivity to environmental cues like light and pH. These factors act as signals that integrate external conditions into internal gene regulatory networks.
   • For example, in plants, miR168 responds to abiotic stresses, while in animals, miR-21 is modulated by pH changes in cancer microenvironments. In microbes, small RNAs adapt to light-driven redox changes.

Conclusion: Light-regulated humidity and pH-dependent miRNA biogenesis significantly shape miRNA abundance, thereby influencing gene expression and development across organisms. These environmental cues act through conserved molecular pathways, with context-specific effects in microbes, plants, and animals.

Several weeks ago, DeepSeek wrote: “In summary, light-regulated humidity and pH-dependent miRNA biogenesis are important mechanisms that influence gene expression and development across diverse organisms by modulating miRNA abundance. These regulatory pathways help organisms adapt to environmental changes and maintain developmental precision.”

Never forget: The claims from Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding 4/15/25 fully support the claims from my model, published as Nutrient-dependent/pheromone-controlled adaptive evolution: a model, and updated with claims linked from angstroms to ecosystems in Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18 (7 years ago), which was reported as:

The angstroms to ecosystems model, proposed by James Kohl, suggests that ecological adaptation is influenced by epigenetic changes, base pair substitutions, and amino acid changes at the molecular level, ultimately affecting pheromone-controlled microRNA/messenger RNA balance and chromosomal rearrangements, according to his ResearchGate profile. Essentially, this model links molecular changes to ecological adaptations through a complex interplay of molecular and physiological processes. 

When others recognize the complexity of the interplay of molecular and physiological processes, unlike Grok, they do not try to link mutations to the evolution of anything, especially pedophilia.

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