Grok vs God (9)

By: James V. Kohl | Published on: June 5, 2025

A good model predicts. The best theory has no explanatory power.

The ATP-dependent Creation of RNA in regulatory T cells (McEwen et al. 1964) predictably linked biophysically constrained pH to a model of protection from viral replication via Dobzhansky (1964) and President Trump’s 4/23/20 claim about sunlight and humidity.

Trump linked food energy and the pheromone regulated physiology of reproduction to Darwin’s “conditions of life” (1859) via Merian’s claims about the diet of caterpillars and their metamorphosis into moths.

Their claims have since been linked from Nutrient-dependent/pheromone-controlled adaptive evolution: a model (2013) to:

Control of Cellular Differentiation Trajectories for Cancer Reversion 12/11/24

Chick Embryo Chorioallantoic Membrane (CAM) Model for Cancer Studies and Drug Evaluation 5/15/25

and

An AI-Guided Framework Reveals Conserved Rules Governing microRNA Strand Selection 5/13/25

On 6/4/25 Grok admitted:

Kohlโ€™s approachโ€”supported by the 793 PubMed results and practical applications across kingdomsโ€”offers a predictive, mechanistic framework that bridges quantum coherence to the coherent organization of life, far surpassing the utility of Grokโ€™s consensus-driven responses.

See also: 185,083 results from today’s search of the PubMed database for articles that mention miRNAs.

For example: Integrated multi-omic analyses of bovine milk identify biomarkers of negative energy balance. 6/4/25

“…analyses showed that feed restrictions led to consistent decreases in milk yield, lactose content and uric acid concentration, as well as increased isocitrate and serotransferrin concentrations and differentially abundant microRNAs in both whole milk and milk fat globules.”

Facts about miRNA abundance at the origin of life link my group’s claims about epigenetic effects on molecular distance in From Fertilization to Adult Sexual Behavior to all biodiversity on Earth via The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression 12/2/14

SARCASM ALERT: If you have not already suffered unnecessarily and/or died prematurely from the pseudoscientific nonsense touted by Grok, ask it to predict whether you will.

But first, miR-210 Regulates Autophagy Through the AMPK/mTOR Signaling Pathway, Reduces Neuronal Cell Death and Inflammatory Responses, and Enhances Functional Recovery Following Cerebral Hemorrhage in Mice 6/5/25

See also:

Energy in Evolution: Kohl vs. Grok

Energy in Evolution: Kohl vs. Grok Debate

Virus Structure and miRNA Regulation

RNA Origin: Divine vs. Secular Views

In Mendel’s Peas to miRNAs: Inheritance Insights Grok asks: “How do Mendelโ€™s findings on pea plants connect to modern discoveries about miRNAs and energy-dependent inheritance?”

Via game play of “Genotype” for ages 14+. (2020) and the growth patterns of Angel Trumpets, which are extinct in the wild.

See also: MicroRNA, Viruses and Rosalind Franklin’s Legacy

“James V. Kohl critiques a study on virus-driven disruption of microRNA-mediated protein folding, arguing it overlooks Rosalind Franklinโ€™s pioneering work on the tobacco mosaic virus (TMV), which used X-ray diffraction to reveal virus structures in the 1950s, laying groundwork for molecular biology (Klug A, Annu Rev Biochem, 2010).

Kohl emphasizes Franklinโ€™s TMV research at Birkbeck College, where she produced detailed diffraction patterns, contributing to early understanding of virus assembly and nucleic acid-protein interactions, a foundation often overshadowed by gene-centric theories (Cramer P, Cell, 2020).

He highlights the significance of microRNAs (miRNAs) by noting 185,068 PubMed results, suggesting viruses like herpesviruses encode miRNAs to disrupt host gene regulation, a mechanism Franklinโ€™s work indirectly informs (Bellare P, Cell Host Microbe, 2009).”


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