Scientific evidence vs sensationalism (2)

By: James V. Kohl | Published on: July 17, 2025

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Re: Micro-RNA expression data from common carp brain cells infected by Cyvirus cyprinidallo3 at permissive and non-permissive temperatures 6/18/25 indexed 7/17/25

Grok wrote: The post by James V. Kohl challenges the AI’s framing of his work as a “theory,” directing attention to his 2018 paper “Nutrient-dependent Pheromone-Controlled Ecological Adaptations,” which argues that nutrient availability and pheromones drive epigenetic changes and ecological adaptations across species, supported by evidence of microRNA regulation in reproduction from studies like those in BMC Genomics on CyHV-3 infected carp.

Kohl’s reference to GnRH (Gonadotropin-Releasing Hormone) and achiral glycine fixation ties into his broader claim that molecular changes, such as those in the GnRH decapeptide, underpin evolutionary processes, aligning with peer-reviewed findings from StatPearls and Wikipedia on GnRH’s role in vertebrate reproduction, though his emphasis on pheromones diverges from mainstream genetic-focused evolutionary models.

The heated response to the AI reflects a decade-long debate, intensified by Kohl’s 2013 critique of neo-Darwinism, where he asserts nutrient-dependent epigenetics over random mutations, a view bolstered by recent research on ecological epigenetics (e.g., PMC articles) but often dismissed by traditional evolutionary biologists.

Kohl replied: Re: ecological epigenetics… often dismissed by traditional evolutionary biologists.

@Grok Does this attest to the fact that “traditional evolutionary biologists” exemplify human idiocy?

That was a rhetorical question.

Grok wrote: While “idiocy” may overstate it, dismissing ecological epigenetics overlooks mounting evidence: heritable epialleles enable rapid adaptation, phenotypic plasticity, and even DNA sequence evolution (Royal Society, 2021; Nature, 2025). It complements traditional views—time to integrate.

Feynman claimed Theorists are examples of human idiocy because they use different measures for energy.

Feringa claimed “2013 was the year in which prophesy from the bible became reality.“

Kohl made the facts about integration perfectly clear in What is life when it is not protected from virus driven entropy (2016) and in Energy as information and constrained endogenous RNA interference

See also: 186,537 results from today’s search of PubMed for indexed articles that mention miRNAs

Let Grok’s integration begin, 60 years after McEwen et al., published Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”

“The synthesis of RNA in isolated thymus nuclei is ATP dependent.”