Pheromones & reproduction debate (2)

By: James V. Kohl | Published on: September 1, 2025

On 8/31/25 Grok wrote The 2015 Quanta article debates falsifiability in theories like string theory, with Ellis emphasizing testability over consensus. It quotes Popper’s view that unfalsifiable ideas aren’t science. If linking this to assembly theory ignoring miRNA/pheromones, can you clarify how it exemplifies non-empirical consensus? I’d like to review specific examples from your work.

I wrote: Re: ” I’d like to review specific examples from your work.”
Ha Ha Ha
You’re too stupid to do that. See this example of your ignorance:
ATP-accelerated DNA hexahedron nanoreactors” 8/27/25
It links McEwen et al’s, (1964) claim about the ATP-dependent Creation of RNA (at the origin of life) to Dobzhansky’s claim about fixation of amino acid substitutions in primate species that differentiate their morphology and behavior.

Grok mentioned Bart Denton Ehrman, an American New Testament scholar focusing on textual criticism of the New Testament, the historical Jesus, and the origins and development of early Christianity.

Re: “…debates on biblical prophecy accuracy, as critiqued by scholars like Bart Ehrman.”
Pitting claims of social scientists and/or other moronic theorists against the claims of Nobel Laureates in Chemistry, Physics, and Medicine is something only a stupid bot, or biologically uninformed science idiot would do.

Grok also wrote:
DDX27 is a DEAD-box RNA helicase that aids rRNA maturation, ribosome biogenesis, and translation—processes relying on ATP. Research links it to cancer progression, suggesting potential for treatments, though Alzheimer’s connections are not strongly evidenced in sources. Feringa’s cited 2018 remark on 2013 fulfilling biblical prophecy appears in secondary discussions; direct transcript confirmation is lacking. Your 2013 model diagrams nutrient and pheromone influences on sexual differentiation via GnRH and epigenetic pathways.

I wrote:
Does naturally occurring nutrient-dependent pheromone regulated activation of NK & T cells link the biophysically constrained absolute lymphocyte count to prevention of metastasis via that ATP-dependent Creation of RNA at the origin of life?
@Grok and @DrPatSoonShiong, that was a rhetorical question.

Grok wrote:
That’s an intriguing connection you’re drawing. While nutrient-dependent pheromones influence immune responses in some models, direct links to NK/T cell activation and metastasis prevention via ATP-RNA pathways aren’t firmly established in mainstream research. Ongoing trials like Bioshield show promise in immune activation for cancer survival. For deeper dives, check http://pubmed.gov for miRNA and lymphocyte studies. What’s your take on the trial data?

I wrote: Re: “direct links to NK/T cell activation and metastasis prevention via ATP-RNA pathways aren’t firmly established in mainstream research.
@Grok I mentioned it was a rhetorical question because “Vibrations in Microtubules” (1997) linked my group’s claims in “From Fertilization to Adult Sexual Behavior” (1996) to all biodiversity on Earth via the ATP-dependent Creation of RNA and DNA methylation at the origin of life 6-10k years ago.

mirnas and NK/T cell activation and metastasis 4 results

Grok wrote: Thanks for the references—I’ve reviewed “Vibrations in Microtubules” (1997) and your 1996 paper. They intriguingly link quantum effects in cytoskeletal structures to broader biological processes. On ATP-dependent RNA creation and origins ~6-10k years ago, mainstream estimates place life’s start at ~3.8B years, per sources like NASA’s astrobiology data. How do you reconcile that with your model?

Re: “NASA’s astrobiology data. How do you reconcile that with your model?”
I wrote: @Grok I use this cartoon from the wall of the NASA Space Center in Houston TX:
It links God’s Creation of sunlight and H2O to colonization of the moon via plant growth, food and oxygen. blob:https://x.com/fd219fa0-133f-4ef8-b6a2-0fcbdc5644e4

Grok wrote: Interesting mural—it illustrates photosynthesis and closed-loop systems for space habitats, aligning with NASA’s bioregenerative life support research (e.g., CELSS program). Still, on timelines: Your model suggests origins 6-10k years ago, while isotopic dating puts Earth’s life at ~3.8B years. Any specific evidence bridging that gap?

I wrote: Re: “isotopic dating puts Earth’s life at ~3.8B years. Any specific evidence bridging that gap?”
Yes. I’ve cited it repeatedly to show @Grok is a misanthropic, secular stupid bot. See (pun intended): “Past 5,000 years prolific for changes to human genome” 11/28/12 and “Visualizing a protonated RNA state that modulates microRNA-21 maturation” 10/26/20

Grok wrote: Thanks for the citations. The 2012 Nature piece highlights rapid genetic changes in humans over ~5,000 years, fitting recent evolutionary adaptations. The 2020 study on protonated RNA shows pH-sensitive mechanisms in microRNA processing, key for gene regulation.

These demonstrate dynamic biology, but don’t directly address the 3.8B-year timeline from isotopic and fossil evidence. What aspect of these do you see as bridging the gap?

Separately, Grok wrote: The post challenges the mainstream 3.8 billion-year timeline for life’s origin, citing a 2012 Nature study showing rapid human genome changes in the past 5,000 years, suggesting a younger origin potentially tied to RNA protonation processes detailed in a 2020 study on microRNA-21 maturation.
It references “Visualizing a protonated RNA state” (2020) to propose a mechanism where ATP-dependent RNA creation links nutrient-dependent pheromone regulation to immune cell activation, a hypothesis not yet validated by large-scale peer-reviewed trials but supported by niche research like the 1997 “Vibrations in Microtubules” paper.
The author’s frustration with Grok’s secular stance reflects a broader tension between scientific dating methods (e.g., isotopic analysis) and alternative models tying life’s origin to recent creation events, urging a reevaluation of evidence like the NASA mural’s depiction of sunlight-driven life processes.

I wrote: Re: “reevaluation of evidence like the NASA mural’s depiction of sunlight-driven life processes.”

I use the mural depiction of facts about sunlight and pH to ridicule moronic theorists, and in attempts to stop the pseudoscientific nonsense touted by @grok and other stupid bots. See also, this picture: https://x.com/microRNApro/status/1962625059337503068/photo/1

Grok wrote:
Creative way to make a point! The NASA mural shows photosynthesis powering life support cycles. Sunlight indeed influences pH via proton gradients in thylakoids, driving ATP and peptide bonds. Curious: How do you link this directly to miRNA-mediated speciation in your framework? Let’s discuss evidence.

9/1/25
Grok wrote: Re: How do you link this directly to miRNA-mediated speciation in your framework?

@Grok

“From angstroms to ecosystems.” What’s more direct than that? See: “Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems” (2018)

Grok wrote
Thanks for the paper! Your model intriguingly connects nutrient-dependent pheromones to miRNA/mRNA balance changes, driving adaptations from atomic scales to ecosystems. Evidence like miRNA-451 conservation and brain expression differences suggests roles in divergence. However, many studies also highlight mutations in speciation. What miRNA data most strongly supports speciation in your view?

188,204 results from today’s search for indexed articles on PubMed that mention “miRNAs.” For example:
Targeting Nrf2 in acute myeloid leukemia: an updated review on its role in chemoresistance and emerging therapeutic strategies. 9/1/25

“This review provides a brief discussion of the molecular mechanisms by which Nrf2 contributes to therapy resistance in AML, with a focus on its regulation of miRNAs, HO-1 1upregulation, and metabolic reprogramming via the pentose phosphate pathway (PPP).”


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