Noncoding RNAs Not So Noncoding Excerpt: “Were there going to be dozens of [micropeptides]? Were there going to be hundreds, like there are hundreds of microRNAs?” says Ingolia. “We just didn’t know.” See also: Number of microRNAs in Human Genome Skyrockets Excerpt: “…researchers from Thomas Jefferson University in Philadelphia have released data that adds another … Secular humanism and ecoterrorism
Practopoiesis A thought results primarily from an adjustment of the brain hardware, and not from a computation executed by that hardware. My comment: The adjustments of the brain hardware integrate RNA-mediated events that include gene duplication and fixation of amino acid substitutions. The nutrient-dependent gene duplications and substitutions link the epigenetic landscape to the physical … Hematopoiesis and practopoiesis
Thanks to Joost G. Wouters for the alert to this nonsense: 1) Michael White in Pacific Standard magazine flatly states that “Epigenetics Is Not Revolutionizing Biology.” 2) Adrian Bird points out in the journal Cell that many of the field’s assumptions and promises remain unproven and are perhaps excessive. 1) White’s article sketches the field’s … Epigenetics Skeptism
Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system Excerpt: The fast-spreading strain AR2F had acquired an additional point mutation in the σ54-dependent EBP gene ntrC, which alters an amino acid (R442C) within the DNA binding domain (Table 1 and table S2). Reported as: Evolutionary Rewiring Strong selective pressure can lead to … RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system Excerpt: The fast-spreading strain AR2F had acquired an additional point mutation in the σ54-dependent EBP gene ntrC, which alters an amino acid (R442C) within the DNA binding domain (Table 1 and table S2). Reported as: Evolutionary Rewiring Strong selective pressure can lead to … RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
Works by Christ et al., continue to attest to the rejuvenating power of blood. For example, in the context of epigenetic pharmacology and regenerative medicine, one protein in the blood has been linked to health via nutrient-dependent amino acid substitutions that differentiate all cell types in all individuals of all species. Simply put, blood seems … Amino acid homeostasis for a Happy New Year!
