If, in some cataclysm, all scientific knowledge were to be destroyed, and only one sentence passed on to the next generation of creatures, what statement would contain the most information in the fewest words? I believe it is the atomic hypothesis, or the atomic fact, or whatever you wish to call it, that all things are made of atoms – little particles that move around in perpetual motion, attracting each other when they are a little distance apart, but repelling upon being squeezed into one another. In that one sentence you will see an enormous amount of information about the world, if just a little imagination and thinking are applied. — as quoted from Richard Feynman
What aspect of energy as information is not already perfectly clear?
Here is a passage in which Lucretius provides a ‘living proof’ of the notion of atoms:
Observe what happens when sunbeams are admitted into a building and shed light on its shadowy places. You will see a multitude of tiny particles mingling in a multitude of ways in the empty space within the light of the beam, as though contending in everlasting conflict, rushing into battle rank upon rank with never a moment’s pause in a rapid sequence of unions and disunions. From this you may picture what it is for the atoms to be perpetually tossed about in the illimitable void… their dancing is an actual indication of underlying movements of matter that are hidden from our sight. There you will see many particles under the impact of invisible blows, changing their course and driven back upon their tracks, this way and that, in all directions. You must understand that they all derive this restlessness from the atoms. It originates with the atoms, which move of themselves. — Lucretius (c. 99 BC – c. 55 BC)
Life on Earth exists only in the context of light energy-induced hydrogen-atom transfer in DNA base pairs in solution.
Sadly, most science journalists and all neo-Darwinian theorists have failed to link the anti-entropic energy of sunlight from Schrodinger’s claims in “What is Life” (1944) to Dobzhansky’s claims about amino acids and cell type differentiation.
…the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla.
The ignorance of most science journalists and all neo-Darwinian theorists attests to the ignorance of all other theorists who failed to link any experimental evidence of biophysically constrained biologically-based cause and effect from angstroms to ecosystems in all living genera. For comparison, serious scientists have linked energy-dependent changes in angstroms to ecosystems via what is known about supercoiled DNA.
Supercoiled DNA protects all organized genomes from virus-driven energy theft and genomic entropy.
The bands in the Terahertz spectrum, moreover, reflected the glycine’s opening and closing motion. The spectrum also incorporated the motion of hydrogen bridges between the glycine and its bound water molecules.
“We can now get the light of life to stay on,” said Romesberg. “That suggests that all of life’s processes can be subject to manipulation.”
All of life’s processes are energy-dependent and sunlight is the anti-entropic source of energy that biophysically constrains RNA-mediated protein folding chemistry. “Creation” of what they think may be a stable semisynthetic organisms will fall short of their claims if the genomic stability of the organism is destroyed by virus-driven energy theft and mRNA degradation, which is linked from mutations to all pathology in species from microbes to humans.
If not for virus-driven energy theft, there would be no need for the nutrient-dependent pheromone-controlled physiology of reproduction in the context of transgenerational epigenetic inheritance that protects the morphological and behavioral phenotypes of species from bacteria to humans. Viruses cause ecologically adapted bacteria to become archaea, and they cause craniofacial deformities and brain development in human infants, who begin to more closely resemble non-human primates. Preventing the virus-driven damage to DNA in all living genera appears to be the concern of these researchers in China.
The team started with the knowledge that viruses use certain amino acids as part of the infection process—they then modified an influenza virus by replacing one such amino acid with another that they had created in the lab—one that does not normally occur in viruses, or people. Without the right amino acid, the virus was still able to function, but it was unable to cause an infection—and because it was still a flu virus, its presence in the body caused the immune system to attack both them and any other type of flu virus encountered, thereby preventing an infection.
In the USA, we have seen researchers consistently frame their experimental evidence in the context of mutations and genomic instability that they claim can somehow be linked from natural selection to evolution. Researcher from other countries seem less likely to believe in that pseudoscientific nonsense or to be motivated only by the prospect of jobs working for pharmaceutical manufacturers.
For example: Brian M. Lamb, co-author of A semisynthetic organism engineered for the stable expansion of the genetic alphabet now serves as a research scientist at Vertex Pharmaceuticals.
See also: Conflict of interest statement: Y.Z., B.M.L., and F.E.R. have filed a patent application based on the use of Cas9 for enforced retention of the UBP. Y.Z. and F.E.R. have filed a patent application for the truncated transporter. F.E.R. has a financial interest (shares) in Synthorx Inc., a company that has commercial interests in the UBP.
See also: RNA-Guided Human Genome Engineering
Let others know when you realize that the climate of academia is not conducive to giving the gifts of science to humanity.
That’s why technological developments, especially those that alter the course of disease are not likely to prevent disease. Treatments make profits. Prevention and/or the Precision Medicine Initiative saves unnecessary suffering and helps to prevent premature death. That is not worth anything to corporate stockholders.