See first: miRNAs  The bold-faced titles of articles will help you to link 145,000 indexed publications about food energy-dependent fixation of amino acids in organized genomes from Peptide synthesis at the origin of life to Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life via microtubules.

Microtubules exist in the context of quantum coherence that link dynamic networks of protein filaments that organize the functional structure of all cell types to coherently organized biology via the fact that MicroRNAs organize intrinsic variation into stem cell states and fact about MicroRNA Involvement in Signaling Pathways During Viral Infection.

Fixation of amino acids in microtubules is the only obvious link from God’s Creation of energy-as-information to supercoiled DNA, which protects organized genomes from the virus-driven degradation of messenger RNA. The ATP-dependent Creation of RNA has been linked from RNA interference to protection from all virus-driven pathology in presentations and publications by all intelligent serious scientists since 1964 .

Unchecked replication of viruses eventually causes extinction in all species. That fact is exemplified by the growth of Angel Trumpets, and other plants in water and sunlight — with no soil, and by the fact that Angel Trumpets are extinct in the wild.

For comparison, most theoretical physicists missed the connection from microtubules to God’s Creation of consciousness via the sense of smell in species from microbes to humans.

The sense of smell links Electron spin changes during general anesthesia in Drosophila, and the Role of olfaction in Octopus vulgaris reproduction from light-activated carbon fixation in cyanobacteria to microRNA-mediated protein folding chemistry via Honeybee Brain Oscillations Are Generated by Microtubules.

The facts that link microtubules to oscillations generated in the honeybee model organism link Nutrient-dependent/pheromone-controlled adaptive evolution: a model, to refutations of stupid theories that try to link Big Bang Cosmology and natural selection for beneficial mutations during the past billions to millions of years of evolution via neo-Darwinian evolution despite the fact that Darwin’s theory started with “conditions of life.”

Energy-dependent conditions of life link microtubules to effective treatment of cancer via the invention of the drug ABRAXANE, which is a microtubule inhibitor.

Microtubule inhibition has also been linked to treatment of dementia via the collection of research reported in the special topic: Exploring the Role of Exosomes in Disease Progression and Therapeutics in Neurodegeneration

George FR Ellis indirectly linked what is known about fixation of amino acid substitutions in microtubules in Top-down causation and quantum physics, which is largely a recapitulation of claims Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems and Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections.

Prevention of all virus-driven pathology from COVID19 to cancer and Alzheimer’s links Sabine Hazan’s claims about microbial peptide synthesis to Thomas E. Ichim’s patents for therapeutic solutions via miRNA-mediated protein folding chemistry and fixation of amino acid substitutions in microtubules.

Facts about Tubulin isotypes can be compared to the claim from A universal trend of amino acid gain and loss in protein evolution that

Amino acid composition of proteins varies substantially between taxa and, thus, can evolve.

Only stupid theorists make claims about proteins that evolved their energy-dependent microRNA-mediated amino acid composition.

A recent comparison of stupid theories to facts was published as: …microtubule-binding protein CSPP1 as a novel cancer biomarker associated with ferroptosis and tumor microenvironment.

See: Exosomal miR-132-3p from mesenchymal stromal cells improves synaptic dysfunction and cognitive decline in vascular dementia.

See also: Biophysical Properties of the Cytoskeleton and Its Role in Neuron Function View all 6 Articles Edited by Stuart Hameroff

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