Alternative Splicings

microRNA-mediated replication timing (1)

The phylogenetic utility and functional constraint of microRNA flanking sequences links the patent for naturally occurring light-activated carbon fixation to viral latency and healthy longevity across kingdoms. The patent: RNA-Guided Human Genome Engineering was linked from functional constraints to gain-of-function research in High-Quality Overlapping Paired-End Reads for the Detection of A-to-I Editing on Small RNA WHO failed to examine the problems associated with gain-of-function research, which researchers now suggest led to the creation of SARs-CoV-2. The creation of SARs-CoV-2 can be…

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Light-activated carbon fixation did not evolve (5)

See first: The tipping point (revisited): 120K 5/12/21 Church Speaks: The cyanobacteria fix [carbon via] light…Under ideal circumstances, they can be maybe seven to ten times more productive per photon.” George M. Church et al patented this naturally occurring process. On 5/12/21, I was pleasantly surprised to see the facts represented in this trail-side placard at Canyonlands National Park. The facts make this patent worthless: RNA-Guided Human Genome Engineering See why: Light-activated binding together of sand and other soil particles…

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Quantum Darwinism (6)

Learn how sunlight and humidity link photosynthesis from construction of the cell wall  to biophysically constrained viral latency via God’s ATP-dependent Creation of RNA.   For links from the light-activated assembly of the microRNA-RNA-peptide nanocomplex across kingdoms via the Creation of enzymes see: Castration increases and androgens decrease nitric oxide synthase activity in the brain: physiologic implications (2000) and Differentiation of Human Induced Pluripotent or Embryonic Stem Cells Decreases the DNA Damage Repair by Homologous Recombination (2017) The nitric oxide…

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Quantum Darwinism (5)

See with my added emphasis: Parallel genetics of regulatory sequences using scalable genome editing in vivo 4/13/21 [Energy-dependent biophysically-constrained microRNA-mediated] Regulatory elements must ultimately be understood within their genomic environment and development- or tissue-specific contexts. Gene-centric theorists are too stupid to start with God’s Creation of energy, which must be linked from regulatory elements to regulation of the genomic environment before the effects of energy can be understood in any context whatsoever. See for context: Energy as information and constrained…

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Quantum Darwinism (3)

“Quantum biology” is quantum Darwinism Starting from…discovery of quantum coherence in low-temperature photosynthetic microbes in 2007, quantum coherence is emerging as a general principle of biological systems. See: MicroRNAs organize intrinsic variation into stem cell states 3/5/20 …naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology. Theorists chose neo-Darwinian pseudoscientific nonsense about beneficial mutations and evolution via natural selection across billions to millions of years instead of the explanatory power of quantum Darwinism. Their ignorance…

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Quantum Darwinism (1)

See first: Pheromones protect us from viruses parts 1-10 For a historical perspective on the development of healthy ecosystems, see: Pheromonal Regulation of Genetic Processes: Research on the House Mouse (Mus musculus L.) (1994) and From Fertilization to Adult Sexual Behavior (1996) For links from quantum Darwinism to all energy-dependent biophysically constrained biodiversity, see also: Quantum Criticality at the Origin of Life 3/3/15 The number of proteins grows exponentially with the number n of amino acids… Peptide synthesis at the…

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Pheromones protect us from viruses (10)

Twitter Profile: MicroRNA.pro, http://Autophagy.pro & http://RNA-mediated.com link subatomic particles from pH-dependent peptide synthesis to sympatric speciation and healthy ecosystems. Before 4/6/21, I had contributed 40,000 tweets @microRNApro to support claims about how light-activated carbon fixation is linked to healthy longevity in more than 118,400 indexed publications that mention ‘microRNA.’ For a historical perspective on the development of healthy ecosystems, see: Pheromonal Regulation of Genetic Processes: Research on the House Mouse (Mus musculus L.) (1994) “The specificity of pheromonal regulation depends…

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Pheromones protect us from viruses (8)

See first: Pheromones protect us from viruses (7) Summary: When others link God’s Creation of anti-entropic virucidal light to pH-dependent biophysically constrained viral latency via His Creation of water, which is required for the creation of all oxygen-dependent life on Earth, we will see how God’s Creation of Genotypes in all species once protected them, and us, from the virus-driven degradation of messenger RNA. More than 118,000 indexed published articles mention ‘microRNA.’ It is long past time for theorists to…

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Pheromones protect us from viruses (7)

It’s been more than one year since Guenther Witzany published What is Life? 3/18/20 “A new definition of life must integrate the current empirical knowledge about interactions between cells, viruses, and RNA networks to provide a better explanatory power than the twentieth century narrative.” The need for the new definition of life is consistent with my claims from “What is life when it is not protected from virus-driven entropy.” It’s been 5 years since this virtual conference presentation on 3/30/16. The…

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Pheromones protect us from viruses (4)

Have you tried and repeatedly failed to put the pieces of a puzzle together? Did you claim it was impossible for anyone else to do it? To me, that exemplifies atheism. This helps to define atheism. Defining the underlying defect in insulin action in type 2 diabetes 3/17/21 …a broad signalling cascade mediated by changes in phosphorylation, gene expression and vesicular trafficking that result in increased nutrient utilisation and storage, and suppression of catabolic processes. The attempt to define the…

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