Alternative Splicings

For God and Country

Diet-driven RNA interference and cancer prevention (4)

Excerpt: What I perceive as apathy can be attributed to the lack of empathy for anyone who suffers from the preventable or controlled virus-driven pathology that, sooner or later, kills us all. In the case of our Vietnam veterans, naturally occurring prevention or effective treatment of glioblastoma might be achieved by dietary intervention with a curcumin supplement. “micrornas”[MeSH Terms] OR “micrornas”[All Fields] OR “microrna”[All Fields] Items: 1 to 20 of 68871 See:  The tipping point (revisited): 68,000 publications 69,000 published…

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Diet-driven RNA interference and cancer prevention (3)

Excerpt: They claim to have found novel autoregulatory feedback loops that link changes in microRNAs to the alternative splicing factors SRSF1 and SRSF2.  Ectopic expression of SRSF1 can automagically repress the level of multiple microRNAs and SRSF2 can automagically upregulate miRNA expression. The fact that a peer-reviewed work published in 2018 links autoregulatory feedback loops to automagically altered gene expression and apoptosis via alternative splicings of pre-mRNAs suggests it is time for all serious scientists to retire. The magic of pseudoscientists has…

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Autophagy is the antiphage defense strategy (2)

2/15/17 Energy as information and constrained endogenous RNA interference (video) The 6.46 minute-long technical presentation (above) from the Precision Medicine Virtual Conference is difficult to understand.Thus, 10 months later, Nik Willmore asked: 12/24/17 What are your insights into CRISPR and mTOR, for a young audience? I’m not mocking you…yet, Humpty Dumpty. What is the basis of your unifying principle? Vibration? Bohmian morphogenetic fields? Modified Darwin? God? –Nik Willmore @nikwillmore 12/25/17 Replying to @nikwillmore @jhewitt123 God created the anti-entropic virucidal energy of sunlight and…

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Enzyme-constrained interethnic biodiversity (6)

I think that I may be able to finish this series before the end of the month and use my tweets to expose more than 100,000  people to what is known about how the energy-dependent creation of microRNAs prevents all pathology. See for one example of more than 68,000 published works: MicroRNA-22 suppresses cell proliferation, migration and invasion in oral squamous cell carcinoma by targeting NLRP3 For an extensive review of biologically-based biophysically constrained viral latency, see: Enzyme-constrained interethnic biodiversity…

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Interethnic genetic similarities and differences

Summary: The facts about interethnic genetic similarities and differences refute all theories about evolved biodiveristy. Ecological variation must be linked to ecological adaptation by what organisms eat and the physiology of pheromone-controlled reproduction. Dobzhansky’s “light” was Schrodinger’s anti-entropic virucidal sunlight and Dobzhansky, a creationist, was joking about millions of years of evolution. He knew that food energy-dependent amino acid substitutions differentiated the cell types of primates. Why don’t you know that? Nothing in Biology Makes Any Sense Except in the…

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Enzyme-constrained interethnic biodiversity (3)

Excerpt: Understanding a “correlational mechanism” is like understanding mutation-driven evolution. You have a mutation. You have evolution. Thus, you understand the simple-minded magic of the correlation. No energy-dependent molecular mechanisms are required. For comparison: Enzyme-constrained interethnic biodiversity is exemplified in Amish populations in the United States of America. Obviously, interethnic difference in genes matter. See: Low cancer incidence rates in Ohio Amish (2009) Why Don’t The Amish Get Cancer? (2016) See also: A null mutation in SERPINE1 protects against biological…

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Enzyme-constrained interethnic biodiversity (1)

Excerpt: Summaries of mutation categories: The summaries attest to the fact that human interethnic biodiversity can be linked to all biodiversity via the food energy-dependent creation of enzymes and the pheromone-controlled physiology of reproduction, which link autophagy to biophysically constrained viral latency. Immune Issue …the findings are “not a show stopper, but the field needs to know about this… Investors are stopping the Zhang-Church-Doudna show. Some were prepared to invest in energy-dependent RNA interference, which biophysically constrains viral latency.The way…

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Quantized energy-dependent viral trophism (3)

Summary: If the pathway is ancestral, how and when did it evolve to protect species from microbes to humans from the virus-driven degradation of their messenger RNA? Peer-Reviewed Science: A “Mathematical Proof of Darwinian Evolution” Is Falsified The theorem addresses only the effects of natural selection. Fisher did not directly address any other effect (mutation, genetic drift, environmental change, etc.) as he considered them to be insignificant. Later mathematicians took issue with Fisher’s lack of rigor, some at considerable length.…

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Quantized energy-dependent viral trophism (2)

See first: Quantized energy-dependent viral trophism Summary of Quantized energy-dependent viral trophism (2) WTH*? The species evolved to F*- itself? (H*eck) (*Fertilize) Rapid genome shrinkage in a self-fertile nematode reveals sperm competition proteins Science  05 Jan 2018 …we compared chromosome-scale assemblies of the outcrossing nematode Caenorhabditis nigoni to its self-fertile sibling species… The chromosome-scale assemblies extend across species to the fact that a difference in the diet of P. pacificus links its pheromone-controlled physiology of reproduction from C. elegans to…

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Lethal virus kills 5 billion people?

A Mathematical Model Links Quantum Physics to Quantum Souls (3)

Thursday, January 4, 2018 at 7 pm Eastern Time: James V. Kohl‏ @jvkohl 42m Your Tweets earned 3,525 impressions over the last 24 hours Please calculate the number of potential victims who might be saved by the information in my tweets. I will sleep better if you know that you may not be among those who survive. —————————————————- See: A Mathematical Model Links Quantum Physics to Quantum Souls (2) See: Viruses exacerbate disease caused by Leishmania parasite How do parasite viruses…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, […]