Alternative Splicings

The eternal significance of microRNAs (7)

Sales of human pheromone-enhanced fragrance products have been virtually eliminated by the pseudoscientific nonsense touted by neo-Darwinian theorists and Big Bang cosmologists. I may revisit their ridiculous claims at ScentofEros.com and Pheromones.com, but prefer to continue moving forward via my other domains: RNA-mediated.com and Autophagy.pro. Summary: 2018 Update: Sympatric speciation has been linked to species diversity as an example of an ecologically validated proof-of-concept in all living genera. Theorists, other psedoscientists and nearly all so-called science journalists have failed to…

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An evolutionary theory killer

ATP and RNA-mediated chromosomal stability

Cytosis, a cell biology game for ages 10+ links ATP to viral latency and the protection of all organized genomes from the virus-driven degradation of messenger RNA that serious scientists have linked to all pathology. It is time for a new measure of cell function: Quantifying Cellular ATP Production Rate…(2018) Adenosine triphosphate (ATP) is the most common high energy intermediate of living organisms. Cells utilize the energy derived from the breakdown of cellular fuels to synthesize ATP from ADP and…

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An evolutionary theory killer

A single base change refutes theistic evolution (2)

Announcing publication of a model that links the creation of quantized energy from changes in subatomic particles to biophysically constrained viral latency and sympatric speciation in all living genera. Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems This angstroms to ecosystems model of ecological adaptation links nutrient energy-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA/messenger RNA balance and chromosomal rearrangements via the physiology of reproduction in species from microbes to humans. The…

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Nutrient-dependent pheromone-controlled feedback loops

Summary: The link from positive selection to one food energy-dependent base pair change and fixation of the mouse-model-to-human-specific EDAR V370A allele in populations on different continents attests to sympatric speciation at every level of examination that refutes the pseudoscientific nonsense of neo-Darwinian mutation-driven evolution. Reported on 5/3/18 as: SWAT team of immune cells found in mother’s milk  1) “There is a feedback loop,” says Yu. It’s known that some immune cells like leucocytes, another white blood cell that fights infection,…

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Ecological Adaptations vs the Randomness of Evolution (2)

Summary: See for comparison: Make ‘Em Resistant to Viruses In the new proposal — which Science says was released in advance of a meeting today — GP-write leaders say “ultrasafe” cells could be developed by making some 400,000 changes to the human genome. A Fast One–Step Digestion of DNA or RNA for Global Detection and Characterization of Nucleotide Modifications (link opens pdf) Product information: The Nucleoside Digestion Mix is an optimized mixture of enzymes that provides a convenient one-step method…

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Ecological Adaptations vs the Randomness of Evolution

Summary: Ecological variation is linked to ecological adaptations in all living genera via the creation of microRNAs and the sense of smell. Odor Perception on the Two Sides of the Brain: Consistency Despite Randomness Highlights •A random model predicts observed preservation of correlations in piriform responses •The model supports consistent agreement about odor quality among individuals The model fails to explain how the energy-dependent creation of microRNAs links pattern recognition to the creation of pre-mRNAs and biophysically constrained viral latency.…

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MicroRNA-mediated autophagy, denuclearization and eusociality

Altruism in a volatile world reported as: The Elusive Calculus of Insects’ Altruism and Kin Selection In 1964, the evolutionary biologist William D. Hamilton seemingly explained one of the greatest paradoxes in biology with a simple mathematical equation. He will be remembered by all serious scientists for his ignorance of top-down energy-dependent causation. For comparison, McEwen et al. (1964), explained energy-dependent ecological adaptation and sympatric speciation by starting with the energy-dependent creation of RNA. See: Dependence of RNA synthesis in…

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Environmental selection is natural selection (4)

Conclusion: Only biologically uninformed science idiots still believe in the pseudoscientific nonsense of neo-Darwinian evolution. VISUALIZING APOPTOSIS AS IT HAPPENS Apoptosis is a highly regulated and critical homeostatic process in multicellular organisms. Biologically uninformed theorists have claimed the conserved molecular mechanisms of energy-dependent apoptosis in multicelluar organisms arose after energy emerged. Aberrations in this form of energy-dependent programmed cell death have been linked from the virus-driven theft of quantized energy to all pathology. That helps to explain why biologically uninformed…

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The eternal significance of microRNAs (6)

Accurate representations of how mutations are linked to the ecological adaptations in viruses that kill us are required to end the stranglehold that pseudoscientists have held on medical research. The pseudoscientists and other theorists make claims about mutation-driven evolution or natural selection and evolution as if the effect of virus-driven energy theft was beneficial to species that have somehow evolved from other species. Neo-Darwinian theories will cause the death of us all. But first they will kill all the chickens.…

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The eternal significance of microRNAs (4)

Conclusion: Conserved energy biophysically constrains viral latency. Metatranscriptomics High-throughput sequencing and analysis of microbial community cDNA are providing valuable insight into in situ microbial activity and metabolism in the oceans. When faced with the eternal significance of quantized energy-dependent natural selection for codon optimality, theorists must attack the basics of what is known to serious scientists about biophysically constrained life on Earth. See for example: Virus-mediated archaeal hecatomb in the deep seafloor By starting with “raw assemblies” instead of the…

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